Macrophage membrane-coated nanocarriers Co-Modified by RVG29 and TPP improve brain neuronal mitochondria-targeting and therapeutic efficacy in Alzheimer's disease mice

Immune cell regulation of glia during CNS injury and disease

(2020) Andrew D. Greenhalgh et al.   NATURE REVIEWS NEUROSCIENCE

Neuronal mitochondria-targeted micelles relieving oxidative stress for delayed progression of Alzheimer's disease

(2020) Peng Yang et al.   BIOMATERIALS

RVG-modified exosomes derived from mesenchymal stem cells rescue memory deficits by regulating inflammatory responses in a mouse model of Alzheimer’s disease

(2019) Guo-hong Cui et al.   Immunity & Ageing

Targeted Drug Delivery to Stroke via Chemotactic Recruitment of Nanoparticles Coated with Membrane of Engineered Neural Stem Cells

(2019) Junning Ma et al.   Small

Mitochondria and Mitochondrial Cascades in Alzheimer’s Disease

(2018) Russell H. Swerdlow   JOURNAL OF ALZHEIMERS DISEASE

Macrophage-Membrane-Coated Nanoparticles for Tumor-Targeted Chemotherapy

(2018) Yu Zhang et al.   NANO LETTERS

Mitochondria-targeting drug conjugates for cytotoxic, anti-oxidizing and sensing purposes: current strategies and future perspectives

(2018) Gantumur Battogtokh et al.   Acta Pharmaceutica Sinica B

Dual-Modified Novel Biomimetic Nanocarriers Improve Targeting and Therapeutic Efficacy in Glioma

(2018) Shiyao Fu et al.   ACS Applied Materials & Interfaces

Liposomes Coated with Isolated Macrophage Membrane Can Target Lung Metastasis of Breast Cancer

(2016) Haiqiang Cao et al.   ACS Nano

Mitochondria-Targeting Ceria Nanoparticles as Antioxidants for Alzheimer’s Disease

(2016) Hyek Jin Kwon et al.   ACS Nano

Nanoformulated alpha-mangostin ameliorates Alzheimer's disease neuropathology by elevating LDLR expression and accelerating amyloid-beta clearance

(2016) Lei Yao et al.   JOURNAL OF CONTROLLED RELEASE

Pair correlation microscopy reveals the role of nanoparticle shape in intracellular transport and site of drug release

(2016) Elizabeth Hinde et al.   Nature Nanotechnology

Enhanced BBB permeability of osmotically active poly(mannitol-co-PEI) modified with rabies virus glycoprotein via selective stimulation of caveolar endocytosis for RNAi therapeutics in Alzheimer's disease

(2015) Tae-Eun Park et al.   BIOMATERIALS

Elevated Mitochondrial Bioenergetics and Axonal Arborization Size Are Key Contributors to the Vulnerability of Dopamine Neurons

(2015) Consiglia Pacelli et al.   CURRENT BIOLOGY

Depletion of microglia and inhibition of exosome synthesis halt tau propagation

(2015) Hirohide Asai et al.   NATURE NEUROSCIENCE

In vitro model of the blood-brain barrier established by co-culture of primary cerebral microvascular endothelial and astrocyte cells

(2015) Ning Wang et al.   Neural Regeneration Research

Protection by genistein on cortical neurons against oxidative stress injury via inhibition of NF-kappaB, JNK and ERK signaling pathway

(2015) Yisong Qian et al.   PHARMACEUTICAL BIOLOGY

Genistein improves spatial learning and memory in male rats with elevated glucose level during memory consolidation

(2015) Yumi Kohara et al.   PHYSIOLOGY & BEHAVIOR

Microglial Malfunction: The Third Rail in the Development of Alzheimer's Disease

(2015) Siddhita D. Mhatre et al.   TRENDS IN NEUROSCIENCES

The Alzheimer's disease mitochondrial cascade hypothesis: Progress and perspectives

(2013) Russell H. Swerdlow et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

Edaravone Ameliorates Oxidative Damage Associated with Aβ25-35 Treatment in PC12 Cells

(2013) Gui-lian Zhang et al.   JOURNAL OF MOLECULAR NEUROSCIENCE

Macrophages offer a paradigm switch for CNS delivery of therapeutic proteins

(2013) Natalia L Klyachko et al.   Nanomedicine

Self-assembly nanomicelles based on cationic mPEG-PLA-b-Polyarginine(R15) triblock copolymer for siRNA delivery

(2012) Zhi-Xia Zhao et al.   BIOMATERIALS

Liposomes loaded with paclitaxel and modified with novel triphenylphosphonium-PEG-PE conjugate possess low toxicity, target mitochondria and demonstrate enhanced antitumor effects in vitro and in vivo

(2012) Swati Biswas et al.   JOURNAL OF CONTROLLED RELEASE

Synthetic nanoparticles functionalized with biomimetic leukocyte membranes possess cell-like functions

(2012) Alessandro Parodi et al.   Nature Nanotechnology

Role of mitochondrial homeostasis and dynamics in Alzheimer's disease

(2012) J. Eva Selfridge et al.   NEUROBIOLOGY OF DISEASE

Engineering of blended nanoparticle platform for delivery of mitochondria-acting therapeutics

(2012) S. Marrache et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Vanadium compounds discriminate hepatoma and normal hepatic cells by differential regulation of reactive oxygen species

(2010) Qin Wang et al.   JOURNAL OF BIOLOGICAL INORGANIC CHEMISTRY

Solubility of Genistein in Water, Methanol, Ethanol, Propan-2-ol, 1-Butanol, and Ethyl Acetate from (280 to 333) K

(2010) Jian-Guo Wu et al.   JOURNAL OF CHEMICAL AND ENGINEERING DATA

Macrophage delivery of therapeutic nanozymes in a murine model of Parkinson’s disease

(2010) Anna M Brynskikh et al.   Nanomedicine

Polyelectrolyte complex optimization for macrophage delivery of redox enzyme nanoparticles

(2010) Yuling Zhao et al.   Nanomedicine

Early deficits in synaptic mitochondria in an Alzheimer's disease mouse model

(2010) H. Du et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Sirtuin regulation of mitochondria: energy production, apoptosis, and signaling

(2010) Eric Verdin et al.   TRENDS IN BIOCHEMICAL SCIENCES

Mitochondrial bioenergetic deficit precedes Alzheimer's pathology in female mouse model of Alzheimer's disease

(2009) J. Yao et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Dose-Dependent Absorption, Metabolism, and Excretion of Genistein in Rats

(2008) Siyuan Zhou et al.   JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY

HT22 hippocampal neuronal cell line possesses functional cholinergic properties

(2008) Jun Liu et al.   LIFE SCIENCES