Article
Chemistry, Multidisciplinary
Luizetta Elliott, Erika E. Salzman, Julia R. Greer
Summary: The research focuses on utilizing benzyl methacrylate-based SMPs to create 3D structures with shape transformation capabilities through two photon lithography. The structures exhibit features such as 500 nm thick petals and 2.5 µm unit cells in cubic lattices.
ADVANCED FUNCTIONAL MATERIALS
(2021)
Review
Chemistry, Multidisciplinary
Hui Zhang, Jiahui Guo, Yu Wang, Luoran Shang, Renjie Chai, Yuanjin Zhao
Summary: In recent years, artificial nerve scaffolds have emerged as a promising alternative for peripheral nerve repair. Natural polymers, with their excellent biocompatibility, low toxicity, high cell affinity, wide source, and environmental protection, are considered ideal biomaterials for tissue engineering scaffolds. The development of natural polymer-derived nerve scaffolds, combined with the integration of exogenous biomolecules, has shown great potential in enhancing nerve regeneration and functional reconstruction.
ADVANCED FUNCTIONAL MATERIALS
(2022)
Review
Polymer Science
Yanli Wu, Yongtao Lu, Ming Zhao, Sergei Bosiakov, Lei Li
Summary: This article discusses the manufacturing process for ideal materials for biological bone tissue engineering from the perspectives of additive manufacturing technology and materials. It reviews the methods and applicable materials in existing additive manufacturing technologies and their applications in biomedicine, as well as the advantages and disadvantages of various AM technologies. The properties of commonly used AM materials, recent developments, and their applications in bone tissue engineering are discussed, along with the main challenges faced by different materials. The development prospects for AM technologies and biomaterials in bone tissue engineering are also considered.
Review
Biochemistry & Molecular Biology
Courtney R. Lynch, Pierre P. D. Kondiah, Yahya E. Choonara
Summary: Tissue engineering involves various aspects of science, medicine, and engineering, focusing on promoting the growth of new cells and tissue components for severe tissue injury and damage treatment. Different biofabrication strategies, including hydrogels, 3D bioprinted scaffolds, and nanotechnology, are vital for this purpose. Biopolymers, specifically those with natural origins, have become increasingly popular due to their biocompatibility, biodegradability, and lack of immune response in the body.
Article
Materials Science, Multidisciplinary
Erica Rosella, Nan Jia, Diego Mantovani, Jesse Greener
Summary: This study presents a microfluidic platform for synthesizing biomembranes and investigating their role as extracellular matrix supports. Different flow conditions during gelation process affect key properties of biomembranes such as width, uniformity, and swelling ratio depending on the biopolymer material used. Cell viability studies on seeded fibroblasts demonstrate the potential for biological applications.
JOURNAL OF MATERIALS SCIENCE & TECHNOLOGY
(2021)
Article
Engineering, Multidisciplinary
Payam Zarrintaj, Farzad Seidi, Mohamadreza Youssefi Azarfam, Mohsen Khodadadi Yazdi, Amir Erfani, Mahmood Barani, Narendra Pal Singh Chauhan, Navid Rabiee, Tairong Kuang, Justyna Kucinska-Lipka, Mohammad Reza Saeb, Masoud Mozafari
Summary: Biomimetic scaffolds play an important role in tissue regeneration and have multifunctional characteristics. Biopolymers, with their unique biocompatibility and biodegradability, are ideal candidates for tissue engineering and regenerative medicine. This article reviews different types of biopolymers and their composites, as well as their interactions with specific cells and tissues. Cellular mechanisms in tissue regeneration are also considered, along with the challenges and improvements required for using biopolymer-based composites in tissue engineering.
COMPOSITES PART B-ENGINEERING
(2023)
Review
Polymer Science
Jingzhi Fan, Keyvan Abedi-Dorcheh, Asma Sadat Vaziri, Fereshteh Kazemi-Aghdam, Saeed Rafieyan, Masoume Sohrabinejad, Mina Ghorbani, Fatemeh Rastegar Adib, Zahra Ghasemi, Kristaps Klavins, Vahid Jahed
Summary: The musculoskeletal system is crucial for movement, organ protection, support, hematopoiesis, and postural stability. Damage to or loss of musculoskeletal tissues greatly affects quality of life. Natural polymers have shown great potential in tissue engineering for musculoskeletal repair.
Article
Nanoscience & Nanotechnology
Alessandra Maria Bossi, Alessio Bucciarelli, Devid Maniglio
Summary: Nanosized biomimetics prepared by molecular imprinting are showing potential as plastic antibodies in medicine for cell imaging and targeted therapies. Utilizing natural polymer silk fibroin to synthesize biocompatible MIP SF-NPs demonstrates high affinity recognition sites and biocompatibility.
ACS APPLIED MATERIALS & INTERFACES
(2021)
Article
Chemistry, Applied
Ameya Sharma, Ishnoor Kaur, Divya Dheer, Manju Nagpal, Pradeep Kumar, D. Nagasamy Venkatesh, Vivek Puri, Inderbir Singh
Summary: Numerous compounds in the oceans have extensive applications in biomedical and biotechnological fields, which make them a prime renewable source of natural substances and promote the development of novel medical systems and devices. Polysaccharides, abundantly present in the marine ecosystem, have advantages such as low extraction costs, solubility in extraction media, interactions with biological compounds, and the ability to be modified for various shapes and sizes. These properties have led to their use as raw materials for drug delivery carrier systems.
CARBOHYDRATE POLYMERS
(2023)
Review
Polymer Science
David Patrocinio, Victor Galvan-Chacon, J. Carlos Gomez-Blanco, Sonia P. Miguel, Jorge Loureiro, Maximiano P. Ribeiro, Paula Coutinho, J. Blas Pagador, Francisco M. Sanchez-Margallo
Summary: Tissue engineering focuses on developing 3D structures through bioprinting techniques using proteins and polysaccharides, but the rheological behaviors of these natural-based bioinks are the main challenge in the cell-laden printing process.
Article
Biochemistry & Molecular Biology
M. Azam Ali, Mozammel Haque Bhuiyan
Summary: The study of biomaterials in brain tissue engineering and neurogenesis is crucial for effective treatment of neurodegenerative diseases, requiring materials that replicate the mechanical and viscoelastic features of the brain. Identifying suitable biomaterials or creating reliable brain-tissue-like biomaterials is a critical gap in current research, with the goal of developing next-generation biomaterials for brain repair.
NEUROCHEMISTRY INTERNATIONAL
(2021)
Article
Materials Science, Multidisciplinary
Zhenyang Ji, Jinrong Yao, Zhengzhong Shao, Xin Chen
Summary: This study developed zein/chitosan composite nanospheres as carriers for controlled release of cinnamaldehyde (CA) in cosmetics industry. The structure of the nanospheres was influenced by the zein/chitosan mass ratio. The interaction between CA and zein, as well as the formation of Schiff base between CA and chitosan, effectively reduced the volatilization rate of CA and prolonged its release time.
Review
Materials Science, Multidisciplinary
Patricia D. C. Costa, Dora C. S. Costa, Tiago R. Correia, Vitor M. Gaspar, Joao F. Mano
Summary: Leveraging 4D biofabrication for engineering biomimetic living constructs is an emerging strategy for recapitulating native tissue dynamics. Carefully selecting smart materials and cell-supporting functionalities is crucial, with the potential to be widely applied in tissue engineering and regenerative medicine.
ADVANCED MATERIALS TECHNOLOGIES
(2021)
Review
Engineering, Biomedical
Alexander B. Cook, Tristan D. Clemons
Summary: The size and shape of polymer materials are increasingly important in scientific fields, with new synthetic methods allowing for the fabrication of anisotropic and shape-defined nanomaterials. Both top-down and bottom-up approaches can produce polymer particles with precise dimensions and unique shapes.
ADVANCED NANOBIOMED RESEARCH
(2022)
Article
Materials Science, Multidisciplinary
Wouter Ruelens, Gilles Koolen, Briac Gricourt, Aart Willem van Vuure, Mario Smet
Summary: Furfuryl alcohol resins with varying amounts of comonomer were synthesized to inhibit the conjugation and crosslinking reactions of the resin. The pre-resins were briefly characterized and then cured to investigate their mechanical properties. The addition of 5% DMFA resulted in a remarkable increase in the strength and strain to failure of the cured resin.
Article
Polymer Science
Wenhai Zhang, Fangxing Ma, Zhaohui Meng, Lingqing Kong, Ziyang Dai, Guangxing Zhao, Anna Zhu, Xiang-Yang Liu, Naibo Lin
Summary: By adjusting the ratio of soft and hard segments, reinforced waterborne polyurethane damping materials with enhanced damping capacity were developed in this study. The ultimate samples demonstrated over 90% damping capacity and toughness exceeding other materials, paving the way for kinetic energy buffering and impact reduction.
MACROMOLECULAR CHEMISTRY AND PHYSICS
(2021)
Article
Chemistry, Physical
Xiaotian Liu, Wenli Zhang, Zaifu Lin, Zhaohui Meng, Chenyang Shi, Zhijun Xu, Likun Yang, Xiang Yang Liu
Summary: Enzymatic biosensors face limitations due to stability issues, but a bio-active porous enzymatic nanofiber membrane has been developed to address this. This membrane, combined with a nanocomposite film, facilitates effective glucose and lactate sensing with long-term stability. The sensors demonstrate high sensitivity, stability, and suitability for real-time sweat analysis during outdoor exercise.
Review
Chemistry, Physical
Guangwei Shao, Rui Yu, Nanliang Chen, Meidan Ye, Xiang Yang Liu
Summary: This review comprehensively discusses the advantages, preparation strategies, and interface issues of stretchable supercapacitors, introduces the research progress of multifunctional stretchable supercapacitors, and highlights the challenges and possible solutions for future development.
Article
Chemistry, Multidisciplinary
Zaifu Lin, Zhaohui Meng, Hao Miao, Ronghui Wu, Wu Qiu, Naibo Lin, Xiang Yang Liu
Summary: The study developed silk fibroin-based ion-exchange membranes for reverse electrodialysis devices, which can provide a stable power supply for biodegradable battery systems. By modifying the nanofibril membranes, dual charge selectivity is generated to regulate ion diffusion for power generation.
Article
Physics, Applied
Caifeng Chen, Hao Wen, Zhenkui Qu, Hao Wang, Xiangyang Liu
Summary: A smart power system of flexible MSC has been developed in this study, utilizing ink-jet printing and electrochemical deposition to fabricate flexible MSC on a modified silk protein film. This system integrates a wireless charging component and a wireless LC voltage sensor, allowing for simultaneous charging and voltage detection, making it suitable for implantable devices with great application potential.
APPLIED PHYSICS LETTERS
(2021)
Article
Nanoscience & Nanotechnology
Qin Li, Deshuai Yu, Chaoyu Fan, Qiaoling Huang, Yonghua Tang, Rongrong Guo, Yifang Huang, Hao Wang, Changxu Lin, Youhui Lin
Summary: The research presented the construction of graphene-gold nanoparticle nanozymes via a one-step hydrothermal reaction, demonstrating efficient dye scavenging ability and catalytic mechanism similar to natural enzymes. The nanozymes may find applications in various research areas such as environmental treatment, sensing, and biotechnology.
ACS APPLIED NANO MATERIALS
(2022)
Article
Chemistry, Multidisciplinary
Fei Xu, Yonghua Tang, Hao Wang, Hongbo Deng, Yanyan Huang, Chaoyu Fan, Jiachen Zhao, Changxu Lin, Youhui Lin
Summary: This study presents a metal ion-mediated self-assembly method to construct catalytically active copper-wool-keratin nanozymes. The optimized hybrids exhibit significant antioxidant activities, making them effective in removing reactive oxygen species. The results demonstrate that nanozymes with advanced catalytic capabilities can be constructed through the self-assembly of metal ions and proteins.
Review
Chemistry, Physical
Rongrong Guo, Deshuai Yu, Sen Wang, Lianlian Fu, Youhui Lin
Summary: This review summarizes the synthesis mechanisms, fundamental properties, and promising applications of nanosheet-incorporated hydrogels. The emphasis is placed on how the nanosheet structure is applied to improve the overall performance of the hydrogel in each application. Additionally, the current challenges and prospects in this area are briefly discussed. We anticipate that the combination of nanosheets and hydrogels will attract more researchers' interest and bring new opportunities in the future.
Article
Chemistry, Multidisciplinary
Shuihong Zhu, Qifan Zhou, Jia Yi, Yihua Xu, Chaoyu Fan, Changxu Lin, Jianyang Wu, Youhui Lin
Summary: The combination of wool keratin (WK) and carbon nanotubes (CNTs) as a structural biomaterial and natural mediator enables the fabrication of flexible and high-performance bioelectronic devices. The WK/CNT composites possess excellent water dispersibility, stability, biocompatibility, and mechanical properties. These composites can be used to design versatile bioelectronics, strain sensors, and integrated gloves for real-time gesture recognition and robot manipulations, demonstrating their great potential in wearable artificial intelligence.
Review
Chemistry, Physical
Yifan Huang, Deshuai Yu, Cong Fu, Rongrong Guo, Chenxu Wu, Youhui Lin
Summary: This article comprehensively reviews the latest progress of crack-resistant hydrogels, including the design principle, crack-resistant strategies, crack-resistant mechanisms, and processes. It also summarizes current challenges and provides an outlook for the future development of crack-resistant hydrogels.
Article
Chemistry, Multidisciplinary
Chaoyu Fan, Yonghua Tang, Hao Wang, Yifan Huang, Fei Xu, Yun Yang, Yangyang Huang, Weifeng Rong, Youhui Lin
Summary: Inspired by the structures of enzymes, researchers have developed a fast and robust method to generate ZIF-90 metallo-nanozymes. ZIF-90 exhibits enzyme-like activity, high stability, and recyclability.
Review
Materials Science, Biomaterials
Shuihong Zhu, Di Wang, Mancai Li, Chuan Zhou, Deshuai Yu, Youhui Lin
Summary: This review focuses on recent advances in flexible and wearable chemo- and bio-sensors based on MXenes, including their preparation, surface modification, and performance. Various chemo- and bio-sensors developed using MXenes are elaborated, highlighting their unique properties, high sensitivity, and selectivity. The review also discusses the applications of MXene-based sensors in the biomedical field and integrated biosensing platforms. The current challenges and future prospects for MXene-based chemo- and bio-sensors are also addressed.
JOURNAL OF MATERIALS CHEMISTRY B
(2022)
Article
Materials Science, Biomaterials
Lianlian Fu, Dijuan Zou, Qiankun Shi, Deshuai Yu, Hao Zhang, Hao Qian, Wenrong Shen, Dongfang Zhou, Youhui Lin
Summary: By utilizing zein as a precursor, carbonized zein nanosheets were prepared with peroxidase- and oxidase-like catalytic activities. C-Zein exhibited high photothermal conversion efficiency and catalytic properties, making it a promising candidate for synergistic photothermal-catalytic cancer treatment.
JOURNAL OF MATERIALS CHEMISTRY B
(2021)
Article
Nanoscience & Nanotechnology
Tong Fu, Chengjie Xu, Rongrong Guo, Changxu Lin, Yanyan Huang, Yonghua Tang, Hao Wang, Qifan Zhou, Youhui Lin
Summary: ZIF-90 nanozyme synthesized from self-assembly of imidazole and metal ions can effectively hydrolyze organophosphorus methyl parathion, showing higher stability and superior recyclability. This work opens up new possibilities for designing and developing other novel nanozymes based on metal-organic framework materials.
ACS APPLIED NANO MATERIALS
(2021)