4.6 Article

Fast and Automated Segmentation for the Three-Directional Multi-Slice Cine Myocardial Velocity Mapping

Journal

DIAGNOSTICS
Volume 11, Issue 2, Pages -

Publisher

MDPI
DOI: 10.3390/diagnostics11020346

Keywords

cardiovascular; segmentation; deep learning

Funding

  1. British Heart Foundation [TG/18/5/34111, PG/16/78/32402]
  2. Heart Research UK [RG2584]
  3. Hangzhou Economic and Technological Development Area Strategical Grant (Imperial Institute of Advanced Technology)
  4. European Research Council Innovative Medicines Initiative on Development of Therapeutics and Diagnostics Combatting Coronavirus Infections Award DRAGON: rapiD and secuRe AI imaging based diaGnosis, stratification, fOllow-up, and preparedness for coronavir [H2020-JTI-IMI2 101005122]
  5. AI for Health Imaging Award CHAIMELEON: Accelerating the Lab to Market Transition of AI Tools for Cancer Management [H2020-SC1-FA-DTS-2019-1 952172]

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The 3Dir MVM technique allows evaluation of cardiac motion in three orthogonal directions. A novel deep learning framework was proposed to accurately delineate myocardial contours in CMR data. The network trained with multi-channel data shows superior performance compared to standard U-Net-based networks trained on single-channel data.
Three-directional cine multi-slice left ventricular myocardial velocity mapping (3Dir MVM) is a cardiac magnetic resonance (CMR) technique that allows the assessment of cardiac motion in three orthogonal directions. Accurate and reproducible delineation of the myocardium is crucial for accurate analysis of peak systolic and diastolic myocardial velocities. In addition to the conventionally available magnitude CMR data, 3Dir MVM also provides three orthogonal phase velocity mapping datasets, which are used to generate velocity maps. These velocity maps may also be used to facilitate and improve the myocardial delineation. Based on the success of deep learning in medical image processing, we propose a novel fast and automated framework that improves the standard U-Net-based methods on these CMR multi-channel data (magnitude and phase velocity mapping) by cross-channel fusion with an attention module and the shape information-based post-processing to achieve accurate delineation of both epicardial and endocardial contours. To evaluate the results, we employ the widely used Dice Scores and the quantification of myocardial longitudinal peak velocities. Our proposed network trained with multi-channel data shows superior performance compared to standard U-Net-based networks trained on single-channel data. The obtained results are promising and provide compelling evidence for the design and application of our multi-channel image analysis of the 3Dir MVM CMR data.

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