A review of toxicity and mechanisms of individual and mixtures of heavy metals in the environment

Temperature and salinity effects on cadmium toxicity on lethal and sublethal responses of Amphibalanus amphitrite nauplii

(2016) Veronica Piazza et al.   ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY

Genotoxic and epigenetic mechanisms in arsenic carcinogenicity

(2014) Elisa Bustaffa et al.   ARCHIVES OF TOXICOLOGY

Heavy metals toxicity: effect of cadmium ions on amyloid beta protein 1–42. Possible implications for Alzheimer’s disease

(2014) Gabriella Notarachille et al.   BIOMETALS

PCBs and Impaired Cochlear Function in Children: Comparing Pre- and Postnatal Exposures

(2014) Julia R. Barrett   ENVIRONMENTAL HEALTH PERSPECTIVES

Toxicological assessment of combined lead and cadmium: Acute and sub-chronic toxicity study in rats

(2014) Guiping Yuan et al.   FOOD AND CHEMICAL TOXICOLOGY

Neurotoxicity from prenatal and postnatal exposure to methylmercury

(2014) Philippe Grandjean et al.   NEUROTOXICOLOGY AND TERATOLOGY

Perinatal Lead (Pb) Exposure Results in Sex-Specific Effects on Food Intake, Fat, Weight, and Insulin Response across the Murine Life-Course

(2014) Christopher Faulk et al.   PLoS One

Environmental Toxins and Parkinson's Disease

(2013) Samuel M. Goldman   Annual Review of Pharmacology and Toxicology

Single and combined effects of cadmium and arsenate in Gammarus pulex (Crustacea, Amphipoda): Understanding the links between physiological and behavioural responses

(2013) Céline Vellinger et al.   AQUATIC TOXICOLOGY

Acute Toxicity of Arsenic under Different Temperatures and Salinity Conditions on the White Shrimp Litopenaeus vannamei

(2013) Jesús Alberto Valentino-Álvarez et al.   BIOLOGICAL TRACE ELEMENT RESEARCH

A screening tool to prioritize public health risk associated with accidental or deliberate release of chemicals into the atmosphere

(2013) David H Blakey et al.   BMC PUBLIC HEALTH

Epigenetic Abnormalities in Cancer Find a “Home on the Range”

(2013) Hariharan Easwaran et al.   CANCER CELL

Arsenic toxicity in the human nerve cell line SK-N-SH in the presence of chromium and copper

(2013) Ligang Hu et al.   CHEMOSPHERE

Proteomic analysis in Daphnia magna exposed to As(III), As(V) and Cd heavy metals and their binary mixtures for screening potential biomarkers

(2013) Thai-Hoang Le et al.   CHEMOSPHERE

Comparison of two mathematical prediction models in assessing the toxicity of heavy metal mixtures to the feeding of the nematode Caenorhabditis elegans

(2013) Jiandong Chen et al.   ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY

The toxicity of cadmium to three aquatic organisms (Photobacterium phosphoreum, Daphnia magna and Carassius auratus) under different pH levels

(2013) R.-J. Qu et al.   ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY

Cytoprotective and antioxidant effects of the edible halophyte Sarcocornia perennis L. (swampfire) against lead-induced toxicity in renal cells

(2013) Manel Gargouri et al.   ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY

Alterations in carbohydrate and protein metabolism in silver catfish (Rhamdia quelen) exposed to cadmium

(2013) Alexandra Pretto et al.   ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY

Combined Toxicity of Lead and Cadmium on Embryogenesis and Early Larval Stages of the European Clam Ruditapes decussatus

(2013) Salem Fathallah et al.   ENVIRONMENTAL ENGINEERING SCIENCE

The Broad Scope of Health Effects from Chronic Arsenic Exposure: Update on a Worldwide Public Health Problem

(2013) Marisa F. Naujokas et al.   ENVIRONMENTAL HEALTH PERSPECTIVES

Determining the bioavailability and toxicity of lead contamination to earthworms requires using a combination of physicochemical and biological methods

(2013) Wei Luo et al.   ENVIRONMENTAL POLLUTION

Unexpected toxic interactions in the freshwater amphipod Gammarus pulex (L.) exposed to binary copper and nickel mixtures

(2013) Jérémie Charles et al.   ENVIRONMENTAL SCIENCE AND POLLUTION RESEARCH

Cadmium in blood of Tunisian men and risk of bladder cancer: interactions with arsenic exposure and smoking

(2013) Molka Feki-Tounsi et al.   ENVIRONMENTAL SCIENCE AND POLLUTION RESEARCH

Simplifying complexity: Mixture toxicity assessment in the last 20 years

(2013) Rolf Altenburger et al.   ENVIRONMENTAL TOXICOLOGY AND CHEMISTRY

Arsenic induced toxicity and histopathological changes in gill and liver tissue of freshwater fish, tilapia (Oreochromis mossambicus)

(2013) Md. Kawser Ahmed et al.   EXPERIMENTAL AND TOXICOLOGIC PATHOLOGY

An update on oxidative stress-mediated organ pathophysiology

(2013) Kahkashan Rashid et al.   FOOD AND CHEMICAL TOXICOLOGY

The potential protective role of lysophospholipid mediators in nephrotoxicity induced by chronically exposed cadmium

(2013) Toshihiko Tsutsumi et al.   FOOD AND CHEMICAL TOXICOLOGY

mRNA and miRNA expression patterns associated to pathways linked to metal mixture health effects

(2013) M. Martínez-Pacheco et al.   GENE

Toxicogenomic approaches for understanding molecular mechanisms of heavy metal mutagenicity and carcinogenicity

(2013) Preeyaporn Koedrith et al.   INTERNATIONAL JOURNAL OF HYGIENE AND ENVIRONMENTAL HEALTH

Environmental risk assessment of combined effects in aquatic ecotoxicology: A discussion paper

(2013) Jonny Beyer et al.   MARINE ENVIRONMENTAL RESEARCH

Molecular features in arsenic-induced lung tumors

(2013) Roland Hubaux et al.   Molecular Cancer

Effects of environmental cadmium exposure on liver function in adults

(2013) Mo-Yeol Kang et al.   OCCUPATIONAL AND ENVIRONMENTAL MEDICINE

Self-Reported Maternal Cigarette Smoke Exposure during the Periconceptional Period and the Risk for Omphalocoele

(2013) Marcia L. Feldkamp et al.   PAEDIATRIC AND PERINATAL EPIDEMIOLOGY

Uptake, Biological Fate, and Toxicity of Metal Oxide Nanoparticles

(2013) Jordi Llop et al.   PARTICLE & PARTICLE SYSTEMS CHARACTERIZATION

DNA Damage and Transcriptional Changes in the Gills of Mytilus galloprovincialis Exposed to Nanomolar Doses of Combined Metal Salts (Cd, Cu, Hg)

(2013) Laura Varotto et al.   PLoS One

Effects on the mobility of metals from acidification caused by possible CO2 leakage from sub-seabed geological formations

(2013) Manoela Romanó de Orte et al.   SCIENCE OF THE TOTAL ENVIRONMENT

Predicting the toxicity of metal mixtures

(2013) Laurie S. Balistrieri et al.   SCIENCE OF THE TOTAL ENVIRONMENT

Repression of miR-143 Mediates Cr (VI)–Induced Tumor Angiogenesis via IGF-IR/IRS1/ERK/IL-8 Pathway

(2013) Jun He et al.   TOXICOLOGICAL SCIENCES

The contribution of heavy metals in cigarette smoke condensate to malignant transformation of breast epithelial cells and in vivo initiation of neoplasia through induction of a PI3K–AKT–NFκB cascade

(2013) Purusottam Mohapatra et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY

In vitro evaluation of cell death induced by cadmium, lead and their binary mixtures on erythrocytes of Common buzzard (Buteo buteo)

(2013) A. Hernández-García et al.   TOXICOLOGY IN VITRO

Co-exposure to lead increases the renal response to low levels of cadmium in metallurgy workers

(2013) R. Hambach et al.   TOXICOLOGY LETTERS

Nephroprotective effect of calcium channel blockers against toxicity of lead exposure in mice

(2013) Jianping Zhang et al.   TOXICOLOGY LETTERS

DNA damage by oxo- and peroxo-chromium(v) complexes: insight into the mutation and carcinogenesis mechanisms

(2013) Lamis Judah et al.   Toxicology Research

The role of native salinity regime on grass shrimp (Palaemonetes pugio) sensitivity to cadmium

(2012) Andrew Y. Oguma et al.   ECOTOXICOLOGY

Antagonistic toxicity of arsenate and cadmium in a freshwater amphipod (Gammarus pulex)

(2012) Céline Vellinger et al.   ECOTOXICOLOGY

Combined toxicity of cadmium and lead on the earthworm Eisenia fetida (Annelida, Oligochaeta)

(2012) Bing Wu et al.   ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY

Exposure to chemical mixtures in Mexican children: high-risk scenarios

(2012) Gabriela Domínguez-Cortinas et al.   ENVIRONMENTAL SCIENCE AND POLLUTION RESEARCH

Calibrating a population-based job-exposure matrix using inspection measurements to estimate historical occupational exposure to lead for a population-based cohort in Shanghai, China

(2012) Dong-Hee Koh et al.   Journal of Exposure Science and Environmental Epidemiology

Developmental lead acetate exposure induces embryonic toxicity and memory deficit in adult zebrafish

(2012) Jiangfei Chen et al.   NEUROTOXICOLOGY AND TERATOLOGY

Tools and perspectives for assessing chemical mixtures and multiple stressors

(2012) Hans Løkke et al.   TOXICOLOGY

Toxicokinetics as a key to the integrated toxicity risk assessment based primarily on non-animal approaches

(2012) Sandra Coecke et al.   TOXICOLOGY IN VITRO

Trace elements and carcinogenicity: a subject in review

(2012) Stephen Juma Mulware   3 Biotech

Heavy Metals Exposure and Hearing Loss in US Adolescents

(2011) Josef Shargorodsky   ARCHIVES OF OTOLARYNGOLOGY-HEAD & NECK SURGERY

Knowns and unknowns on burden of disease due to chemicals: a systematic review

(2011) Annette Prüss-Ustün et al.   Environmental Health

Biomarkers of Methylmercury Exposure Immunotoxicity among Fish Consumers in Amazonian Brazil

(2011) Jennifer F. Nyland et al.   ENVIRONMENTAL HEALTH PERSPECTIVES

Toxicity, Accumulation, and Removal of Heavy Metals by Three Aquatic Macrophytes

(2011) A. Basile et al.   INTERNATIONAL JOURNAL OF PHYTOREMEDIATION

Antagonistic effects of cadmium on lead accumulation in pregnant and non-pregnant mice

(2011) Euan Smith et al.   JOURNAL OF HAZARDOUS MATERIALS

Mechanisms of methylmercury-induced neurotoxicity: Evidence from experimental studies

(2011) Marcelo Farina et al.   LIFE SCIENCES

Non-coding RNAs in human disease

(2011) Manel Esteller   NATURE REVIEWS GENETICS

Associations of blood lead with estimated glomerular filtration rate using MDRD, CKD-EPI and serum cystatin C-based equations

(2011) J. T. Spector et al.   NEPHROLOGY DIALYSIS TRANSPLANTATION

Reversal and Prevention of Arsenic-Induced Human Bronchial Epithelial Cell Malignant Transformation by microRNA-200b

(2011) Zhishan Wang et al.   TOXICOLOGICAL SCIENCES

Arsenic Exposure and Toxicology: A Historical Perspective

(2011) Michael F. Hughes et al.   TOXICOLOGICAL SCIENCES

Advances in metal-induced oxidative stress and human disease

(2011) Klaudia Jomova et al.   TOXICOLOGY

Cadmium and transport of ions and substances across cell membranes and epithelia

(2010) Emmy Van Kerkhove et al.   BIOMETALS

Cadmium exposure in the population: from health risks to strategies of prevention

(2010) Tim S. Nawrot et al.   BIOMETALS

Genome-wide conserved consensus transcription factor binding motifs are hyper-methylated

(2010) Mun-Kit Choy et al.   BMC GENOMICS

Metal exposures in an inner-city neonatal population

(2010) Elizabeth A. Jones et al.   ENVIRONMENT INTERNATIONAL

Effects of Mercury onDictyostelium discoideum: Proteomics Reveals the Molecular Mechanisms of Physiological Adaptation and Toxicity

(2010) Francesco Marsano et al.   JOURNAL OF PROTEOME RESEARCH

Systems toxicology approaches for understanding the joint effects of environmental chemical mixtures

(2010) David J. Spurgeon et al.   SCIENCE OF THE TOTAL ENVIRONMENT

Heavy metal levels (Pb, Cd, Cr and Hg) in the adult general population near an urban solid waste incinerator

(2010) Miren Begoña Zubero et al.   SCIENCE OF THE TOTAL ENVIRONMENT

A novel model integrated concentration addition with independent action for the prediction of toxicity of multi-component mixture

(2010) Li-Tang Qin et al.   TOXICOLOGY

Exposure to Pb, Cd, and As mixtures potentiates the production of oxidative stress precursors: 30-day, 90-day, and 180-day drinking water studies in rats

(2010) Margaret H. Whittaker et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY

Effects of arsenic exposure on DNA methylation and epigenetic gene regulation

(2010) John F Reichard et al.   Epigenomics

Arsenic-Induced Carcinogenesis—Oxidative Stress as a Possible Mode of Action and Future Research Needs for More Biologically Based Risk Assessment

(2009) Kirk T. Kitchin et al.   CHEMICAL RESEARCH IN TOXICOLOGY

Cellular uptake, subcellular distribution and toxicity of arsenic compounds in methylating and non-methylating cells

(2009) E. Dopp et al.   ENVIRONMENTAL RESEARCH

Protective effect of Aquilegia vulgaris (L.) against lead acetate-induced oxidative stress in rats

(2009) Aziza A. El-Nekeety et al.   FOOD AND CHEMICAL TOXICOLOGY

Probucol Increases Glutathione Peroxidase-1 Activity and Displays Long-Lasting Protection against Methylmercury Toxicity in Cerebellar Granule Cells

(2009) Marcelo Farina et al.   TOXICOLOGICAL SCIENCES

Inhibition of erythrocyte phosphoribosyltransferases (APRT and HPRT) by Pb2+: A potential mechanism of lead toxicity

(2009) I. Baranowska-Bosiacka et al.   TOXICOLOGY

Role of oxidative stress in cadmium toxicity and carcinogenesis

(2009) Jie Liu et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY

Differential Toxicity to Cd, Pb, and Cu in Dragonfly Larvae (Insecta: Odonata)

(2008) V. D. Tollett et al.   ARCHIVES OF ENVIRONMENTAL CONTAMINATION AND TOXICOLOGY

Low dose mixture effects of endocrine disrupters: implications for risk assessment and epidemiology

(2008) Andreas Kortenkamp   INTERNATIONAL JOURNAL OF ANDROLOGY

Roles of biomarkers in evaluating interactions among mixtures of lead, cadmium and arsenic

(2008) Gensheng Wang et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY

Molecular mechanisms triggered by mercury

(2007) GianPaolo Guzzi et al.   TOXICOLOGY