Metabolomics of Cerebrospinal Fluid from Healthy Subjects Reveal Metabolites Associated with Ageing

Biochemical Differences in Cerebrospinal Fluid between Secondary Progressive and Relapsing–Remitting Multiple Sclerosis

(2019) Stephanie Herman et al.   Cells

Local and systemic metabolic alterations in brain, plasma, and liver of rats in response to aging and ischemic stroke, as detected by nuclear magnetic resonance (NMR) spectroscopy

(2019) Umadevi V. Wesley et al.   NEUROCHEMISTRY INTERNATIONAL

Longitudinal plasma metabolomics of aging and sex

(2019) Burcu F. Darst et al.   Aging-US

Ageing as a risk factor for neurodegenerative disease

(2019) Yujun Hou et al.   Nature Reviews Neurology

Global metabolic profiling to model biological processes of aging in twins

(2019) Bryan J. Bunning et al.   AGING CELL

Life Expectancy and Mortality Rates in the United States, 1959-2017

(2019) Steven H. Woolf et al.   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

The plasma metabolome as a predictor of biological aging in humans

(2019) Lawrence C. Johnson et al.   GeroScience

Diurnal Patterns for Cortisol, Cortisone and Agouti-Related Protein in Human Cerebrospinal Fluid and Blood

(2019) Sunil K Panigrahi et al.   JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM

Application of Metabolomics in Alzheimer’s Disease

(2018) Jordan Maximillian Wilkins et al.   Frontiers in Neurology

Untargeted Metabolite Profiling of Cerebrospinal Fluid Uncovers Biomarkers for Severity of Late Infantile Neuronal Ceroid Lipofuscinosis (CLN2, Batten Disease)

(2018) Miriam Sindelar et al.   Scientific Reports

Integration of magnetic resonance imaging and protein and metabolite CSF measurements to enable early diagnosis of secondary progressive multiple sclerosis

(2018) Stephanie Herman et al.   Theranostics

Recent trends in life expectancy across high income countries: retrospective observational study

(2018) Jessica Y Ho et al.   BMJ-British Medical Journal

Metabolomic investigations in cerebrospinal fluid of Parkinson's disease

(2018) Desiree Willkommen et al.   PLoS One

Mass spectrometry based metabolomics for in vitro systems pharmacology: pitfalls, challenges, and computational solutions

(2017) Stephanie Herman et al.   Metabolomics

Distinct metabolomic signature in cerebrospinal fluid in early parkinson's disease

(2017) Jean-Pierre Trezzi et al.   MOVEMENT DISORDERS

Cerebrospinal fluid metabolomic profiles can discriminate patients with leptomeningeal carcinomatosis from patients at high risk for leptomeningeal metastasis

(2017) Byong Chul Yoo et al.   Oncotarget

Biological Age Predictors

(2017) Juulia Jylhävä et al.   EBioMedicine

Metabolite patterns predicting sex and age in participants of the Karlsruhe Metabolomics and Nutrition (KarMeN) study

(2017) Manuela J. Rist et al.   PLoS One

Metabolic drift in the aging brain

(2016) Julijana Ivanisevic et al.   Aging-US

OpenMS: a flexible open-source software platform for mass spectrometry data analysis

(2016) Hannes L Röst et al.   NATURE METHODS

Individual variability in human blood metabolites identifies age-related differences

(2016) Romanas Chaleckis et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Integration of ‘omics’ data in aging research: from biomarkers to systems biology

(2015) Jonas Zierer et al.   AGING CELL

Methionine restriction and life-span control

(2015) Byung Cheon Lee et al.   Annals of the New York Academy of Sciences

A proposed panel of biomarkers of healthy ageing

(2015) Jose Lara et al.   BMC Medicine

limma powers differential expression analyses for RNA-sequencing and microarray studies

(2015) Matthew E. Ritchie et al.   NUCLEIC ACIDS RESEARCH

Cerebrospinal fluid metabolomics reveals altered waste clearance and accelerated aging in HIV patients with neurocognitive impairment

(2014) Edana Cassol et al.   AIDS

Metabolomic profiling in multiple sclerosis: insights into biomarkers and pathogenesis

(2014) SN Reinke et al.   Multiple Sclerosis Journal

Methionine restriction extends lifespan of Drosophila melanogaster under conditions of low amino-acid status

(2014) Byung Cheon Lee et al.   Nature Communications

The Hallmarks of Aging

(2013) Carlos López-Otín et al.   CELL

Metabolomic markers reveal novel pathways of ageing and early development in human populations

(2013) Cristina Menni et al.   INTERNATIONAL JOURNAL OF EPIDEMIOLOGY

Human serum metabolic profiles are age dependent

(2012) Zhonghao Yu et al.   AGING CELL

Ageing as a Risk Factor for Disease

(2012) Teresa Niccoli et al.   CURRENT BIOLOGY

A cross-platform toolkit for mass spectrometry and proteomics

(2012) Matthew C Chambers et al.   NATURE BIOTECHNOLOGY

Reduced cerebrospinal fluid level of thyroxine in patients with Alzheimer's disease

(2012) Per Johansson et al.   PSYCHONEUROENDOCRINOLOGY

Increased Levels of Plasma Acylcarnitines in Obesity and Type 2 Diabetes and Identification of a Marker of Glucolipotoxicity

(2010) Stephanie J. Mihalik et al.   Obesity

Folinic acid-responsive seizures are identical to pyridoxine-dependent epilepsy

(2009) Renata C. Gallagher et al.   ANNALS OF NEUROLOGY

Monoamines, BDNF, IL-6 and corticosterone in CSF in patients with Parkinson’s disease and major depression

(2009) Sven Pålhagen et al.   JOURNAL OF NEUROLOGY

The human cerebrospinal fluid metabolome

(2008) David S. Wishart et al.   JOURNAL OF CHROMATOGRAPHY B-ANALYTICAL TECHNOLOGIES IN THE BIOMEDICAL AND LIFE SCIENCES

Analysis of the adult human plasma metabolome

(2008) Kay A Lawton et al.   PHARMACOGENOMICS

Gender-related and age-related urinalysis of healthy subjects by NMR-based metabonomics

(2007) Nikolaos G. Psihogios et al.   NMR IN BIOMEDICINE