Article
Chemistry, Applied
Meng Cheng, Yingjun Cui, Yanli Guo, Peixin Zhao, Juan Wang, Rongfei Zhang, Xiangyou Wang
Summary: pH-responsive CC/SA/CA hydrogels were prepared using CC and SA as wall materials, with the hydrogel formation attributed to electrostatic interactions and hydrogen bonding. The hydrogels exhibited improved thermostability with increasing CC content, as well as increased swelling degree with higher pH of the buffer solution. CA release from the hydrogels was mainly controlled by Fickian diffusion, and the release rate was positively correlated with temperature and environmental pH, allowing for on-demand release of CA. The hydrogels also showed good storage stability, antioxidant and antibacterial activities, and biocompatibility, making them a promising platform for environmentally-responsive preservatives with precise release and intelligent preservation capabilities.
Article
Biochemistry & Molecular Biology
Nuo Wei, Ze Lv, Xiaohan Meng, Qianwei Liang, Tianzhen Jiang, Shaoyang Sun, Yan Li, Jianguo Feng
Summary: The development of controlled release formulations for agrochemicals has been driven by increasing concerns about environmental pollution. In this study, a convenient polysaccharide hydrogel was successfully prepared for the controlled release of a specific agrochemical. The hydrogel exhibited excellent agrochemical load capacity and encapsulation efficiency. It also showed promising protective properties for the encapsulated agrochemical, resulting in better control against a specific plant disease. Safety assessment studies further demonstrated the hydrogel's good biocompatibility with non-targeted organisms and the crop.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2023)
Article
Biochemistry & Molecular Biology
Qian Liu, Zhenrong Tan, Dafeng Zheng, Xueqing Qiu
Summary: A magnetic delivery system for targeted drug was developed using aminated lignosulfonate (ALS) and carboxymethyl chitosan (CMCS) to fabricate nano Fe3O4 with pH responsiveness. The system successfully loaded doxorubicin hydrochloride (DOX) and demonstrated controlled release of the drug. The particle size ranged from 79.9-169.9 nm under optimized conditions and exhibited excellent pH responsiveness. The drug-loaded particles showed significant growth inhibition on cancer cells.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2023)
Article
Chemistry, Multidisciplinary
Ahmed Mohamed Omer, Wagih Abdel-Alim Sadik, Abdel-Ghaffar Maghraby El-Demerdash, Heba Shawky Hassan
Summary: This study aimed to develop efficient pH-sensitive hydrogel based on aminated chitosan (AmCs) and gelatin (Gel) biopolymers for oral drug delivery. The developed AmCs-Gel crosslinked hydrogel displayed variable pH-sensitive swelling profiles and showed acceptable biodegradability with no cellular toxicity, suggesting their applicability as pH-sensitive oral drug carriers. Adjusting the ratios of AmCs and Gel can achieve variable drug release and loading efficiency.
JOURNAL OF SAUDI CHEMICAL SOCIETY
(2021)
Article
Biochemistry & Molecular Biology
Tongyao Zhao, Xiaoyan Li, Yumei Gong, Yanzhu Guo, Fengyu Quan, Qiang Shi
Summary: The study focused on the binary blending of sodium alginate and quaternary ammonium chitosan to fabricate composite fibers. The results showed changes in solution state and electrical potential at different mass ratios, leading to the production of fibers with excellent properties.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2021)
Article
Biochemistry & Molecular Biology
Dong Yang, Lei Gong, Qing Li, Bo Fan, Cuiluan Ma, Yu-Cai He
Summary: By using chitosan and sodium carboxymethyl cellulose as raw materials, a polyelectrolyte complex (PEC) was successfully prepared through strong electrostatic interaction. The reactive contact area between the two bio-based polyelectrolytes was enlarged by preparing a crosslinked vacuolar structure without the use of a cross-linker. The yield and bibulous rate of PEC were significantly affected by the preparation conditions, yielding a PEC with 71.2% yield when pH, CMC-Na-to-CTS ratio, stirring speed, and reaction temperature were optimized.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2023)
Article
Biochemistry & Molecular Biology
Radheshyam Samanta, Sukanta Nayak, Biswarup Das, Amit Kumar Nayak
Summary: This research aimed to develop and assess a sustained stomach-specific ofloxacin delivery system using single-unit hydrodynamically balanced system (HBS)-based floating capsules. The floating capsules were prepared by incorporating cationic-natured low molecular mass chitosan (LMMCH) and anionic-natured carboxymethyl tamarind gum (CMTG). The results showed that no drug-polymer interaction occurred within these formulated ofloxacin HBS capsules. The best formulation, composed of 75 mg LMMCH and 25 mg CMTG, exhibited excellent in vitro floatation behavior in simulated gastric fluid (pH 1.2) for 6 hours and demonstrated prolonged stomach-specific retention in an in vivo X-ray imaging study. These HBS floating capsules have the potential for stomach-specific delivery of other drugs.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2023)
Article
Biochemistry & Molecular Biology
Haibin Zhang, Zhiyang Gu, Wenya Li, Lili Guo, Litong Wang, Lan Guo, Saibo Ma, Baoqin Han, Jing Chang
Summary: Oral drug delivery is the most preferred mode of treatment due to its convenience and non-invasiveness. However, delivering protein drugs orally has been a challenge. This study developed a novel OCMC/SA nanohydrogel that solves this problem, with high drug loading capacity and passive drug targeting function.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2022)
Article
Chemistry, Applied
Huijuan Jing, Xin Huang, Xiaojing Du, Ling Mo, Chaoyang Ma, Hongxin Wang
Summary: In this study, a novel synthesis strategy utilizing hydrogen bonds was used to prepare sodium alginate/carboxymethyl chitosan hydrogel beads. The beads demonstrated excellent pH sensitivity, reversibility, and protein loading capacity, making them a potential carrier for oral delivery of proteins.
CARBOHYDRATE POLYMERS
(2022)
Article
Polymer Science
Sureerat Thuekeaw, Kris Angkanaporn, Suwabun Chirachanchai, Chackrit Nuengjamnong
Summary: The study introduces the concept of porous double-layered polymer in microcapsule form with dual pH responsiveness for controlled release application. By using a combination of anionic sodium alginate and cationic chitosan, the double-layered microcapsules, CS-SA, can effectively incorporate active ingredients like basil oil. The release performances confirm the retention of antioxidant and antimicrobial activities of basil oil under storage and various digestive conditions.
POLYMER DEGRADATION AND STABILITY
(2021)
Article
Biochemistry & Molecular Biology
Jiaqi Zhang, Christopher Hurren, Zhentan Lu, Dong Wang
Summary: This study developed a pH-sensitive sodium alginate hydrogel for combating bacterial infection caused by tissue damage. The hydrogel showed fast drug release rate and effective antibacterial activity under weak acid conditions.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2022)
Article
Polymer Science
Julien Es Sayed, Cleïment Caito, Abinaya Arunachalam, Armin Amirsadeghi, Larissa van Westerveld, Denise Maret, Roshan Akdar Mohamed Yunus, Eleonora Calicchia, Olivia Dittberner, Giuseppe Portale, Daniele Parisi, Marleen Kamperman
Summary: Complex coacervates are versatile materials formed by electrostatic associations between polyelectrolytes. The viscoelastic properties of these materials can be easily altered by the ionic strength of the medium, resulting in a range of materials from liquids to gels. This study reveals the importance of intermolecular hydrogen bonds on the phase behavior and viscoelasticity of HA-CHI complex coacervates. The density of hydrogen bonds between CHI units increases with pH, leading to elastic gel-like behavior. This pH-dependent behavior is relevant for the design of polyelectrolyte materials.
Article
Chemistry, Applied
Yaowen Liu, Yanlan Ma, Yan Liu, Jinlu Zhang, Md Alomgir Hossen, Dur E. Sameen, Jianwu Dai, Suqing Li, Wen Qin
Summary: Intelligent packaging for detecting food spoilage is in demand, and in this study, gelatin and chitosan were used to prepare microcapsules for monitoring food freshness. The microcapsules showed enhanced thermal stability and controlled release of curcumin, which enabled sustainable pH-change sensing and colorimetric indicator capability for monitoring pork deterioration during storage.
FOOD HYDROCOLLOIDS
(2022)
Article
Materials Science, Multidisciplinary
Zunaira Huma Ghauri, Atif Islam, Muhammad Abdul Qadir, Abdul Ghaffar, Nafisa Gull, Maryam Azam, Azra Mehmood, Atif Ali Ghauri, Rafi Ullah Khan
Summary: The pH-sensitive hydrogels based on polyelectrolyte complex of chitosan/sodium alginate/PEG with 1,4-diaminobutane as a cross-linking agent were successfully prepared by solution casting method, exhibiting good hydrogel properties and drug release performance.
MATERIALS CHEMISTRY AND PHYSICS
(2022)
Article
Chemistry, Applied
Chunli Xu, Lidong Cao, Muhammad Bilal, Chong Cao, Pengyue Zhao, Hongjun Zhang, Qiliang Huang
Summary: Carboxymethyl chitosan (CMCS) is a promising biopolymer carrier for controlled release formulations of pesticides. In this study, a manganese-based carboxymethyl chitosan hydrogel was prepared to encapsulate and release fungicide prothioconazole in a controllable manner, with faster release in neutral and slightly alkaline solutions.
CARBOHYDRATE POLYMERS
(2021)
Article
Polymer Science
Bassant Yousry Eweida, Ahmed Mohamed Omer, Tamer Mahmoud Tamer, Hesham Abd-Elfatah Mohamed Soliman, Ahmed Amin Zaatot, Mohamed Samir Mohy-Eldin
Summary: A novel Chitosan-g-Octanal Schiff base adsorbent, synthesized through click chemistry, showed excellent performance in the removal of heavy crude oil spills compared to native Chitosan adsorbent, with higher oil adsorption percentages and faster adsorption rates. The adsorption process followed the pseudo-second order model and fitted well with the Langmuir model, indicating it to be an endothermic, favorable, and spontaneous process.
Review
Chemistry, Multidisciplinary
Yang Xu, Ahmed K. Rashwan, Ahmed Osman, Eman M. Abd El-Monaem, Ahmed M. Elgarahy, Abdelazeem S. Eltaweil, Mirna Omar, Yuting Li, Abul-Hamd E. Mehanni, Wei Chen, David W. Rooney
Summary: Metal-organic frameworks have various applications such as food packaging and drug delivery, but their use in food and pharmaceutical fields is limited due to toxicity concerns during preparation.
ENVIRONMENTAL CHEMISTRY LETTERS
(2023)
Article
Chemistry, Applied
Abdelazeem S. Eltaweil, Eman M. Abd El-Monaem, Gehan M. El-Subruiti, Bassma M. Ali, Mona M. Abd El-Latif, Ahmed M. Omer
Summary: New porous adsorbent beads were developed by incorporating graphene oxide (GO) into cellulose acetate beads (CA) for the removal of methylene blue (MB) dye. The adsorption of MB dye increased with increasing GO ratio, following the PSO kinetic model and Langmuir isotherm model. The maximum adsorption capacity reached 369.85 mg/g. The adsorption mechanism involved electrostatic interactions, H-bonding, van der Waals forces, n-pi and pi-pi interactions. The beads exhibited excellent recycling ability and high selectivity towards MB molecules in the presence of co-existing cations.
JOURNAL OF POROUS MATERIALS
(2023)
Article
Environmental Sciences
Nehad. A. A. Elmaghraby, Ahmed. M. M. Omer, El-Refaie Kenawy, Mohamed Gaber, Safaa Ragab, Ahmed El Nemr
Summary: This study successfully fabricated a nanofiber composite of cellulose acetate/activated carbon (CA/AC) using the electrospinning technique. The CA/AC nanofiber composite demonstrated a high oil adsorption capacity and stability. The incorporation of activated carbon into the nanofiber mats improved the oil adsorption capacity, and the composite material showed consistent adsorption performance even after multiple recycling.
ENVIRONMENTAL SCIENCE AND POLLUTION RESEARCH
(2023)
Review
Chemistry, Multidisciplinary
Ahmed I. Osman, Eman M. Abd El-Monaem, Ahmed M. Elgarahy, Chukwunonso O. Aniagor, Mohamed Hosny, Mohamed Farghali, Emanne Rashad, Marcel I. Ejimofor, Eduardo A. Lopez-Maldonado, Ikko Ihara, Pow-Seng Yap, David W. Rooney, Abdelazeem S. Eltaweil
Summary: Access to drinkable water is increasingly challenging due to pollution and high cost of traditional water treatment methods. Biological sorbents made from biomass waste offer a promising and sustainable alternative. These sorbents effectively remove contaminants and promote circular economy. Different types of sorbents, preparation methods, adsorption mechanisms, and regeneration processes are discussed in this review.
ENVIRONMENTAL CHEMISTRY LETTERS
(2023)
Review
Chemistry, Multidisciplinary
Ahmed I. Osman, Mohamed Hosny, Abdelazeem S. Eltaweil, Sara Omar, Ahmed M. Elgarahy, Mohamed Farghali, Pow-Seng Yap, Yuan-Seng Wu, Saraswathi Nagandran, Kalaivani Batumalaie, Subash C. B. Gopinath, Oliver Dean John, Mahendran Sekar, Trideep Saikia, Puvanan Karunanithi, Mohd Hayrie Mohd Hatta, Kolajo Adedamola Akinyede
Summary: Microplastic pollution is a growing concern for human health as microplastics have been found in various ecosystems. This review discusses the sources, formation, occurrence, toxicity, and remediation methods of microplastics. It highlights the distinction between ocean-based and land-based sources, and the impact of microplastic exposure on human health and the aquatic ecosystem.
ENVIRONMENTAL CHEMISTRY LETTERS
(2023)
Review
Chemistry, Multidisciplinary
Ahmed I. Osman, Mohamed Farghali, Ikko Ihara, Ahmed M. Elgarahy, Amir Ayyad, Neha Mehta, Kim Hoong Ng, Eman M. Abd M. El-Monaem, Abdelazeem S. Eltaweil, Mohamed Hosny, Seham M. Hamed, Samer Fawzy, Pow-Seng Yap, David W. Rooney
Summary: Climate change necessitates the development of advanced carbon-neutral and circular methods for material and fuel production. This review focuses on the pyrolysis of algal and lignocellulosic biomass, analyzing the various products and mechanisms involved, as well as exploring techniques for upgrading the resulting oil. The economic viability and environmental impact of this process are also evaluated through life cycle assessments. The study finds that product yields are significantly influenced by the pyrolysis method and identifies key factors controlling the distribution of pyrolysis products. Furthermore, the potential of biochar in carbon dioxide sequestration and the economic feasibility of biochar and bio-oil generation are discussed.
ENVIRONMENTAL CHEMISTRY LETTERS
(2023)
Review
Chemistry, Multidisciplinary
Ahmed I. Osman, Ahmed M. Elgarahy, Abdelazeem S. Eltaweil, Eman M. Abd El-Monaem, Hisham G. El-Aqapa, Yuri Park, Yuhoon Hwang, Ali Ayati, Mohamed Farghali, Ikko Ihara, Ala'a H. Al-Muhtaseb, David W. Rooney, Pow-Seng Yap, Mika Sillanpaa
Summary: In response to the energy crisis and environmental pollution, research on efficient methods such as environmental catalysis for biofuel production and water purification has increased. Environmental catalysis involves the use of green catalysts to break down pollutants and produce chemicals without generating undesirable by-products. This review focuses on environmental photocatalysis, biocatalysis, and electrocatalysis, covering catalyst synthesis, structure, and applications. Biomass-derived materials, metal-organic frameworks, non-noble metals nanoparticles, nanocomposites, and enzymes are common catalysts. Water pollutants can be efficiently degraded using heterogeneous Fenton catalysis, with degradation rates ranging from 71.7% to 100%. Photocatalysis can produce dihydrogen (H-2) at a generation rate exceeding 100 μmol h(-1), while methane cracking yields dihydrogen ranging from 27% to 88%. Biodiesel production ranges from 48.6% to 99%.
ENVIRONMENTAL CHEMISTRY LETTERS
(2023)
Article
Pharmacology & Pharmacy
Basma H. Naiel, Gehan M. El-Subruiti, Randa E. Khalifa, Abdelazeem S. Eltaweil, Ahmed M. Omer
Summary: New floatable polymeric beads were developed for efficient encapsulation and prolonged release of amoxicillin trihydrate. The beads were composed of alginate/iota carrageenan doubly networked polymeric beads, entrapped with sunflower oil, and surface-coated with aminated chitosan. Various analysis tools were employed to investigate the properties of the beads, which showed excellent floating ability exceeding 24 hours and successful encapsulation of 93.29% of the drug.
JOURNAL OF DRUG DELIVERY SCIENCE AND TECHNOLOGY
(2023)
Article
Chemistry, Multidisciplinary
Abdelazeem S. Eltaweil, Maha S. Ahmed, Gehan M. El-Subruiti, Randa E. Khalifa, Ahmed M. Omer
Summary: New composite microbeads composed of carboxylated graphene oxide (CGO) impregnated into alginate (Alg) microbeads and coated with aminated chitosan (AmCs) layer were developed. The microbeads exhibited pH-sensitivity and the concentration of CGO and AmCs greatly influenced their swelling behavior and protection of Alg microbeads. The composite microbeads showed improved drug loading efficiency and sustained release of ciprofloxacin (CIP) compared to Alg microbeads.
ARABIAN JOURNAL OF CHEMISTRY
(2023)
Article
Agricultural Engineering
Dhirar Ben Salem, Abdelkader Ouakouak, Fouzia Touahra, Noureddine Hamdi, Abdelazeem S. Eltaweil, Asad Syed, Ramaraj Boopathy, Hai Nguyen Tran
Summary: This study aimed to develop a new material, MBA-bead, by combining the properties of magnetic-biochar derived from peanut shells and hydrogel bead, and investigate its ability to adsorb Cu2+ in water. The MBA-bead contained a high water content of around 90% and had a diameter of approximately 3 mm (wet form) and 2 mm (dried form). It exhibited a specific surface area of 262.4 m(2)/g and a total pore volume of 0.751 cm(3)/g. The Langmuir maximum adsorption capacity of MBA-bead for Cu2+ was found to be 234.1 mg/g at 30 degrees C and pH(eq) 5.0. The primary adsorption mechanisms involved complexation, ion exchange, and Van der Waals force. Furthermore, the laden MBA-bead could be reused multiple times after desorbing with NaOH or HCl. The cost estimation for producing the materials indicated that MBA-bead has potential as an effective adsorbent for removing Cu2+ ions from water.
BIORESOURCE TECHNOLOGY
(2023)
Article
Chemistry, Applied
Ahmed M. Omer, Gehad S. Elgarhy, Gehan M. El-Subruiti, Eman M. Abd El-Monaem, Abdelazeem S. Eltaweil
Summary: Self-floating Ni-FeLDH@MWCNT@CA microbeads were prepared and showed strong adsorption ability for Cr6+. The adsorption occurred via electrostatic interactions, inner/outer sphere complexations, ion exchange, and reduction mechanisms. The microbeads also exhibited excellent reusability for five cycles.
CARBOHYDRATE POLYMERS
(2023)
Article
Multidisciplinary Sciences
Ahmed M. Omer, Abdelazeem S. Eltaweil, Esmail M. El-Fakharany, Eman M. Abd El-Monaem, Magda M. F. Ismail, Mohamed S. Mohy-Eldin, Mohammed S. Ayoup
Summary: This study developed a novel bioactive chitosan Schiff base (CTS-SB) derivative by coupling chitosan (CTS) with 4-((5, 5-dimethyl-3-oxocyclohex-1-en-1-yl) amino) benzene-sulfonamide. The CTS-SB derivative exhibited enhanced antibacterial, anticancer, and antidiabetic activities compared to pure CTS. It showed improved ion exchange capacity, increased antibacterial activity against Escherichia coli and Staphylococcus aureus bacteria, higher inhibitory values of alpha-amylase and alpha-glucosidase, and potential anticancer activity.
ARABIAN JOURNAL FOR SCIENCE AND ENGINEERING
(2023)
Article
Multidisciplinary Sciences
Ahmed M. Omer, Tamer M. Tamer, Mohamed E. Hassan, Randa E. Khalifa, Eman M. Abd El-Monaem, Abdelazeem S. Eltaweil, Mohamed S. Mohy Eldin
Summary: The present study successfully developed an efficient superabsorbent hydrogel for water conservation and slow release of Ethephon. Through analysis and experiments, it was found that the grafted hydrogel made from modified cellulose and hydrophilic monomers has good water absorption capacity and nutrient carrying ability, which can be applied in agricultural production of sandy soil.
ARABIAN JOURNAL FOR SCIENCE AND ENGINEERING
(2023)
