Positive Effects of NPY1 Receptor Activation on Islet Structure Are Driven by Pancreatic Alpha- and Beta-Cell Transdifferentiation in Diabetic Mice
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Title
Positive Effects of NPY1 Receptor Activation on Islet Structure Are Driven by Pancreatic Alpha- and Beta-Cell Transdifferentiation in Diabetic Mice
Authors
Keywords
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Journal
Frontiers in Endocrinology
Volume 12, Issue -, Pages -
Publisher
Frontiers Media SA
Online
2021-02-25
DOI
10.3389/fendo.2021.633625
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- (2019) Ryan A. Lafferty et al. DIABETES OBESITY & METABOLISM
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- (2016) Nathan Lawlor et al. GENOME RESEARCH
- Evidence of β-Cell Dedifferentiation in Human Type 2 Diabetes
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