Targeted suicide gene therapy for liver cancer based on ribozyme-mediated RNA replacement through post-transcriptional regulation

A global view of hepatocellular carcinoma: trends, risk, prevention and management

(2019) Ju Dong Yang et al.   Nature Reviews Gastroenterology & Hepatology

Therapeutic applications of group I intron-based trans -splicing ribozymes

(2018) Chang Ho Lee et al.   Wiley Interdisciplinary Reviews-RNA

Preclinical safety evaluation of hepatic arterial infusion of oncolytic poxvirus

(2018) Euna Cho et al.   Drug Design Development and Therapy

Global, Regional, and National Cancer Incidence, Mortality, Years of Life Lost, Years Lived With Disability, and Disability-Adjusted Life-years for 32 Cancer Groups, 1990 to 2015

(2017) et al.   JAMA Oncology

Image-aided Suicide Gene Therapy Utilizing Multifunctional hTERT-targeting Adenovirus for Clinical Translation in Hepatocellular Carcinoma

(2016) Yun-Hee Kim et al.   Theranostics

Transarterial injection of recombinant human type-5 adenovirus H101 in combination with transarterial chemoembolization (TACE) improves overall and progressive-free survival in unresectable hepatocellular carcinoma (HCC)

(2015) Xiao-jun Lin et al.   BMC CANCER

Targeted anticancer effect through microRNA-181a regulated tumor-specific hTERT replacement

(2015) You-Sub Won et al.   CANCER LETTERS

Targeted Regression of Hepatocellular Carcinoma by Cancer-Specific RNA Replacement through MicroRNA Regulation

(2015) Juhyun Kim et al.   Scientific Reports

High frequency of telomerase reverse-transcriptase promoter somatic mutations in hepatocellular carcinoma and preneoplastic lesions

(2013) Jean Charles Nault et al.   Nature Communications

Viral Vector-Based Therapeutic Cancer Vaccines

(2011) Cecilia Larocca et al.   CANCER JOURNAL

Intracellular efficacy of tumor-targeting group I intron-based trans-splicing ribozyme

(2011) Byung-Su Kwon et al.   JOURNAL OF GENE MEDICINE

Evolving strategies for the treatment of hepatocellular carcinoma: From clinical-guided to molecularly-taylored therapeutic options

(2010) Luca Faloppi et al.   CANCER TREATMENT REVIEWS

Regional Liver Therapy Using Oncolytic Virus to Target Hepatic Colorectal Metastases

(2010) Susanne G. Carpenter et al.   SEMINARS IN ONCOLOGY

Loss of miR-122 expression in liver cancer correlates with suppression of the hepatic phenotype and gain of metastatic properties

(2009) C Coulouarn et al.   ONCOGENE

Validation of tissue-specific promoter-driven tumor-targeting trans-splicing ribozyme system as a multifunctional cancer gene therapy device in vivo

(2008) M-S Song et al.   CANCER GENE THERAPY

Antitumor Effects of Systemically Delivered Adenovirus Harboring Trans-Splicing Ribozyme in Intrahepatic Colon Cancer Mouse Model

(2008) J.-S. Jeong et al.   CLINICAL CANCER RESEARCH

MicroRNA-122, a tumor suppressor microRNA that regulates intrahepatic metastasis of hepatocellular carcinoma

(2008) Wei-Chih Tsai et al.   HEPATOLOGY

In Vivo Reprogramming of hTERT by Trans-splicing Ribozyme to Target Tumor Cells

(2007) Seung-Hee Hong et al.   MOLECULAR THERAPY

Adenovirus vector induced innate immune responses: Impact upon efficacy and toxicity in gene therapy and vaccine applications

(2007) Zachary C. Hartman et al.   VIRUS RESEARCH