Low Distribution of TIM-3+ Cytotoxic Tumor-Infiltrating Lymphocytes Predicts Poor Outcomes in Gastrointestinal Stromal Tumors

Interaction of Breast Cancer and Insulin Resistance on PD1 and TIM3 Expression in Peripheral Blood CD8 T Cells

(2019) Miriam Victoria Martín-Manzo et al.   PATHOLOGY & ONCOLOGY RESEARCH

Aberrant accumulation of Dickkopf 4 promotes tumor progression via forming the immune suppressive microenvironment in gastrointestinal stromal tumor

(2019) Ming Wang et al.   Cancer Medicine

Identifying Secondary Mutations in Chinese Patients with Imatinib-Resistant Gastrointestinal Stromal Tumors (GISTs) by Next Generation Sequencing (NGS)

(2019) Jiang Du et al.   PATHOLOGY & ONCOLOGY RESEARCH

Low TIM3 expression indicates poor prognosis of metastatic prostate cancer and acts as an independent predictor of castration resistant status

(2017) Junlong Wu et al.   Scientific Reports

Upregulation of T-cell Immunoglobulin and Mucin-Domain Containing-3 (Tim-3) in Monocytes/Macrophages Associates with Gastric Cancer Progression

(2016) Zhenxin Wang et al.   IMMUNOLOGICAL INVESTIGATIONS

Get the GIST? An overview of gastrointestinal stromal tumours

(2016) G. A. Watson et al.   IRISH JOURNAL OF MEDICAL SCIENCE

Classifying Cancers Based on T-cell Infiltration and PD-L1

(2015) Michele W.L. Teng et al.   CANCER RESEARCH

Increased Tim-3 expression in peripheral NK cells predicts a poorer prognosis and Tim-3 blockade improves NK cell-mediated cytotoxicity in human lung adenocarcinoma

(2015) Liyun Xu et al.   INTERNATIONAL IMMUNOPHARMACOLOGY

T-cell immunoglobulin mucin-3 expression in bladder urothelial carcinoma: Clinicopathologic correlations and association with survival

(2015) Meng Yang et al.   JOURNAL OF SURGICAL ONCOLOGY

Tim-3 expression represents dysfunctional tumor infiltrating T cells in renal cell carcinoma

(2015) Chen Cai et al.   WORLD JOURNAL OF UROLOGY

Apoptosis of tumor infiltrating effector TIM-3+CD8+ T cells in colon cancer

(2015) Chiao-Wen Kang et al.   Scientific Reports

The Coordinated Actions of TIM-3 on Cancer and Myeloid Cells in the Regulation of Tumorigenicity and Clinical Prognosis in Clear Cell Renal Cell Carcinomas

(2015) Y. Komohara et al.   Cancer Immunology Research

High FoxP3 expression in tumour cells predicts better survival in gastric cancer and its role in tumour microenvironment

(2014) G-F Ma et al.   BRITISH JOURNAL OF CANCER

Managing GIST in the imatinib era: optimization of adjuvant therapy

(2014) Jonathan C Trent et al.   Expert Review of Anticancer Therapy

Regulation of T cell responses by the receptor molecule Tim-3

(2014) Jacob V. Gorman et al.   IMMUNOLOGIC RESEARCH

CTHRC1 Acts as a Prognostic Factor and Promotes Invasiveness of Gastrointestinal Stromal Tumors by Activating Wnt/PCP-Rho Signaling

(2014) Ming-Ze Ma et al.   NEOPLASIA

Gastrointestinal Stromal Tumors

(2013) Joseph Vadakara et al.   HEMATOLOGY-ONCOLOGY CLINICS OF NORTH AMERICA

Tim-3 Expression Defines Regulatory T Cells in Human Tumors

(2013) Jing Yan et al.   PLoS One

Up-Regulation of PD-L1, IDO, and Tregs in the Melanoma Tumor Microenvironment Is Driven by CD8+ T Cells

(2013) S. Spranger et al.   Science Translational Medicine

TIM3+FOXP3+regulatory T cells are tissue-specific promoters of T-cell dysfunction in cancer

(2013) Kaori Sakuishi et al.   OncoImmunology

Tim-3/galectin-9 signaling pathway mediates T-cell dysfunction and predicts poor prognosis in patients with hepatitis B virus-associated hepatocellular carcinoma

(2012) Hang Li et al.   HEPATOLOGY

Colocalization of Inflammatory Response with B7-H1 Expression in Human Melanocytic Lesions Supports an Adaptive Resistance Mechanism of Immune Escape

(2012) J. M. Taube et al.   Science Translational Medicine

Coexpression of Tim-3 and PD-1 identifies a CD8+ T-cell exhaustion phenotype in mice with disseminated acute myelogenous leukemia

(2011) Q. Zhou et al.   BLOOD

Imatinib potentiates antitumor T cell responses in gastrointestinal stromal tumor through the inhibition of Ido

(2011) Vinod P Balachandran et al.   NATURE MEDICINE

Targeting Tim-3 and PD-1 pathways to reverse T cell exhaustion and restore anti-tumor immunity

(2010) Kaori Sakuishi et al.   JOURNAL OF EXPERIMENTAL MEDICINE