(Dys)regulation of Synaptic Activity and Neurotransmitter Release by β-Amyloid: A Look Beyond Alzheimer's Disease Pathogenesis

Mild behavioral impairment is associated with β-amyloid but not tau or neurodegeneration in cognitively intact elderly individuals

(2020) Firoza Z. Lussier et al.   Alzheimers & Dementia

Amyloid-β and Synaptic Vesicle Dynamics: A Cacophonic Orchestra

(2019) Francesca Fagiani et al.   JOURNAL OF ALZHEIMERS DISEASE

A resurrection of aducanumab for Alzheimer's disease

(2019) Lon Schneider   LANCET NEUROLOGY

Risk of Conversion to Dementia in a Mild Behavioral Impairment Group Compared to a Psychiatric Group and to a Mild Cognitive Impairment Group

(2018) Fernando E. Taragano et al.   JOURNAL OF ALZHEIMERS DISEASE

The effect of amyloid-β peptide on synaptic plasticity and memory is influenced by different isoforms, concentrations and aggregation status

(2018) Walter Gulisano et al.   NEUROBIOLOGY OF AGING

The Physiological Roles of Amyloid-β Peptide Hint at New Ways to Treat Alzheimer's Disease

(2018) Holly M. Brothers et al.   Frontiers in Aging Neuroscience

Cognitive and emotional alterations in App knock-in mouse models of Aβ amyloidosis

(2018) Yasufumi Sakakibara et al.   BMC NEUROSCIENCE

Correction: Association of anxiety with subcortical amyloidosis in cognitively normal older adults

(2018) Bernard J. Hanseeuw et al.   MOLECULAR PSYCHIATRY

Beta-amyloid short- and long-term synaptic entanglement

(2018) Cristina Lanni et al.   PHARMACOLOGICAL RESEARCH

Synapsin I phosphorylation is dysregulated by beta-amyloid oligomers and restored by valproic acid

(2017) Jade Marsh et al.   NEUROBIOLOGY OF DISEASE

Physiological Concentrations of Amyloid Beta Regulate Recycling of Synaptic Vesicles via Alpha7 Acetylcholine Receptor and CDK5/Calcineurin Signaling

(2017) Vesna Lazarevic et al.   Frontiers in Molecular Neuroscience

Efficacy and safety of anti-amyloid-β immunotherapy for Alzheimer's disease: a systematic review and network meta-analysis

(2017) Jia-Jie Mo et al.   Annals of Clinical and Translational Neurology

Specific Neuromodulatory Actions of Amyloid-β on Dopamine Release in Rat Nucleus Accumbens and Caudate Putamen

(2017) Elisa Mura et al.   JOURNAL OF ALZHEIMERS DISEASE

Alzheimer's Disease and the Amyloid-β Peptide

(2017) M. Paul Murphy et al.   JOURNAL OF ALZHEIMERS DISEASE

Subtle behavioral changes and increased prefrontal-hippocampal network synchronicity in APPNL−G−F mice before prominent plaque deposition

(2017) Amira Latif-Hernandez et al.   BEHAVIOURAL BRAIN RESEARCH

Neuropsychiatric symptoms as early manifestations of emergent dementia: Provisional diagnostic criteria for mild behavioral impairment

(2016) Zahinoor Ismail et al.   Alzheimers & Dementia

Time-dependent reversal of synaptic plasticity induced by physiological concentrations of oligomeric Aβ42: an early index of Alzheimer’s disease

(2016) Peter Koppensteiner et al.   Scientific Reports

Amyloid-β Oligomers May Impair SNARE-Mediated Exocytosis by Direct Binding to Syntaxin 1a

(2015) Yoosoo Yang et al.   Cell Reports

Cerebrospinal Fluid β-Amyloid1–42 Levels in the Differential Diagnosis of Alzheimer’s Disease—Systematic Review and Meta-Analysis

(2015) Jin-A Mo et al.   PLoS One

Effects of soluble β-amyloid on the release of neurotransmitters from rat brain synaptosomes

(2014) Guendalina Olivero et al.   Frontiers in Aging Neuroscience

Apathy correlates with prefrontal amyloid   deposition in Alzheimer's disease

(2013) T. Mori et al.   JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY

Protein Misfolded Oligomers: Experimental Approaches, Mechanism of Formation, and Structure-Toxicity Relationships

(2012) Francesco Bemporad et al.   CHEMISTRY & BIOLOGY

Dual Effect of Beta-Amyloid on α7 and α4β2 Nicotinic Receptors Controlling the Release of Glutamate, Aspartate and GABA in Rat Hippocampus

(2012) Elisa Mura et al.   PLoS One

Amyloid-β Acts as a Regulator of Neurotransmitter Release Disrupting the Interaction between Synaptophysin and VAMP2

(2012) Claire L. Russell et al.   PLoS One

A Paravascular Pathway Facilitates CSF Flow Through the Brain Parenchyma and the Clearance of Interstitial Solutes, Including Amyloid  

(2012) J. J. Iliff et al.   Science Translational Medicine

Beta Amyloid Differently Modulate Nicotinic and Muscarinic Receptor Subtypes which Stimulate in vitro and in vivo the Release of Glycine in the Rat Hippocampus

(2012) Stefania Zappettini et al.   Frontiers in Pharmacology

Amyloid-related imaging abnormalities in amyloid-modifying therapeutic trials: Recommendations from the Alzheimer’s Association Research Roundtable Workgroup

(2011) Reisa A. Sperling et al.   Alzheimers & Dementia

Effects of Age and Amyloid Deposition on Aβ Dynamics in the Human Central Nervous System

(2011) Yafei Huang   ARCHIVES OF NEUROLOGY

Role of Key Aromatic Residues in the Ligand-binding Domain of α7 Nicotinic Receptors in the Agonist Action of β-Amyloid

(2011) Mei Tong et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Endogenous amyloid-β is necessary for hippocampal synaptic plasticity and memory

(2010) Daniela Puzzo et al.   ANNALS OF NEUROLOGY

β-Amyloid activates presynaptic α7 nicotinic acetylcholine receptors reconstituted into a model nerve cell system: involvement of lipid rafts

(2010) Ghous M. Khan et al.   EUROPEAN JOURNAL OF NEUROSCIENCE

Specific inhibitory effect of amyloid-β on presynaptic muscarinic receptor subtypes modulating neurotransmitter release in the rat nucleus accumbens

(2010) M. Grilli et al.   NEUROSCIENCE

Decreased Clearance of CNS  -Amyloid in Alzheimer's Disease

(2010) K. G. Mawuenyega et al.   SCIENCE

Picomolar Amyloid-  Positively Modulates Synaptic Plasticity and Memory in Hippocampus

(2009) D. Puzzo et al.   JOURNAL OF NEUROSCIENCE

 -Amyloid Monomers Are Neuroprotective

(2009) M. L. Giuffrida et al.   JOURNAL OF NEUROSCIENCE

Amyloid-β as a positive endogenous regulator of release probability at hippocampal synapses

(2009) Efrat Abramov et al.   NATURE NEUROSCIENCE

Structure-neurotoxicity relationships of amyloid  -protein oligomers

(2009) K. Ono et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Amyloid-  Dynamics Are Regulated by Orexin and the Sleep-Wake Cycle

(2009) J.-E. Kang et al.   SCIENCE