Mycobacterium smegmatis GlnR Regulates the Glyoxylate Cycle and the Methylcitrate Cycle on Fatty Acid Metabolism by Repressing icl Transcription

Metabolic engineering strategies based on secondary messengers (p)ppGpp and c-di-GMP to increase erythromycin yield in Saccharopolyspora erythraea

(2019) Zhen Xu et al.   ACS Synthetic Biology

The Nitrogen Regulator GlnR Directly Controls Transcription of the prpDBC Operon Involved in Methylcitrate Cycle in Mycobacterium smegmatis

(2019) Wei-Bing Liu et al.   JOURNAL OF BACTERIOLOGY

Mycobacterium tuberculosis requires glyoxylate shunt and reverse methylcitrate cycle for lactate and pyruvate metabolism

(2019) Agnese Serafini et al.   MOLECULAR MICROBIOLOGY

Nitrogen regulator GlnR directly controls transcription of genes encoding lysine deacetylases in Actinobacteria

(2017) Ying Xu et al.   MICROBIOLOGY-SGM

Systematic Identification ofMycobacterium tuberculosisEffectors Reveals that BfrB Suppresses Innate Immunity

(2017) Xiang He et al.   MOLECULAR & CELLULAR PROTEOMICS

Acetyl-CoA synthetases ofSaccharopolyspora erythraeaare regulated by the nitrogen response regulator GlnR at both transcriptional and post-translational levels

(2017) Di You et al.   MOLECULAR MICROBIOLOGY

Glyoxylate detoxification is an essential function of malate synthase required for carbon assimilation inMycobacterium tuberculosis

(2017) Susan Puckett et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Lactate oxidation facilitates growth of Mycobacterium tuberculosis in human macrophages

(2017) Sandra Billig et al.   Scientific Reports

GlnR and PhoP Directly Regulate the Transcription of Genes Encoding Starch-Degrading, Amylolytic Enzymes in Saccharopolyspora erythraea

(2016) Ya Xu et al.   APPLIED AND ENVIRONMENTAL MICROBIOLOGY

Chewing the fat: lipid metabolism and homeostasis during M. tuberculosis infection

(2016) Rustin R Lovewell et al.   CURRENT OPINION IN MICROBIOLOGY

Reciprocal Regulation of GlnR and PhoP in Response to Nitrogen and Phosphate Limitations in Saccharopolyspora erythraea

(2015) Li-li Yao et al.   APPLIED AND ENVIRONMENTAL MICROBIOLOGY

Latent Mycobacterium tuberculosis Infection

(2015) Haileyesus Getahun et al.   NEW ENGLAND JOURNAL OF MEDICINE

Nitrogen regulator GlnR controls uptake and utilization of non-phosphotransferase-system carbon sources in actinomycetes

(2015) Cheng-Heng Liao et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Three genes encoding citrate synthases inSaccharopolyspora erythraeaare regulated by the global nutrient-sensing regulators GlnR, DasR, and CRP

(2014) Cheng-Heng Liao et al.   MOLECULAR MICROBIOLOGY

Methylcitrate cycle defines the bactericidal essentiality of isocitrate lyase for survival ofMycobacterium tuberculosison fatty acids

(2014) Hyungjin Eoh et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Genome wide analysis of the complete GlnR nitrogen-response regulon in Mycobacterium smegmatis

(2013) Victoria A Jenkins et al.   BMC GENOMICS

Feast or famine: the host-pathogen battle over amino acids

(2013) Yanjia J. Zhang et al.   CELLULAR MICROBIOLOGY

Reversible acetylation regulates acetate and propionate metabolism in Mycobacterium smegmatis

(2013) J. D. Hayden et al.   MICROBIOLOGY-SGM

A Novel Role of the PrpR as a Transcription Factor Involved in the Regulation of Methylcitrate Pathway in Mycobacterium tuberculosis

(2012) Paweł Masiewicz et al.   PLoS One

Genome-wide analysis of the role of GlnR in Streptomyces venezuelae provides new insights into global nitrogen regulation in actinomycetes

(2011) Steven T Pullan et al.   BMC GENOMICS

1H NMR-based Metabolomic Profiling in Mice Infected withMycobacterium tuberculosis

(2011) Ji-Hyun Shin et al.   JOURNAL OF PROTEOME RESEARCH

Understanding Latent Tuberculosis: A Moving Target

(2010) P. L. Lin et al.   JOURNAL OF IMMUNOLOGY

The Streptomyces coelicolor GlnR regulon: identification of new GlnR targets and evidence for a central role of GlnR in nitrogen metabolism in actinomycetes

(2010) Yvonne Tiffert et al.   MOLECULAR MICROBIOLOGY

Evaluation of the Mycobacterium smegmatis and BCG models for the discovery of Mycobacterium tuberculosis inhibitors

(2010) Mudassar Altaf et al.   TUBERCULOSIS

Nitrogen Control in Mycobacterium smegmatis: Nitrogen-Dependent Expression of Ammonium Transport and Assimilation Proteins Depends on the OmpR-Type Regulator GlnR

(2008) J. Amon et al.   JOURNAL OF BACTERIOLOGY

Functional Characterization of a Vitamin B12-Dependent Methylmalonyl Pathway in Mycobacterium tuberculosis: Implications for Propionate Metabolism during Growth on Fatty Acids

(2008) S. Savvi et al.   JOURNAL OF BACTERIOLOGY