Botanical Medicines Cryptolepis sanguinolenta, Artemisia annua, Scutellaria baicalensis, Polygonum cuspidatum, and Alchornea cordifolia Demonstrate Inhibitory Activity Against Babesia duncani

Drug screening of food and drug administration-approved compounds against Babesia bovis in vitro

(2020) Yongchang Li et al.   EXPERIMENTAL PARASITOLOGY

Synergistic Mechanisms of Constituents in Herbal Extracts during Intestinal Absorption: Focus on Natural Occurring Nanoparticles

(2020) Qing Zhao et al.   Pharmaceutics

Dried Leaf Artemisia Annua Improves Bioavailability of Artemisinin via Cytochrome P450 Inhibition and Enhances Artemisinin Efficacy Downstream

(2020) Matthew R. Desrosiers et al.   Biomolecules

Management strategies for human babesiosis

(2020) Robert P. Smith et al.   Expert Review of Anti-Infective Therapy

Plant-Based Antidiabetic Nanoformulations: The Emerging Paradigm for Effective Therapy

(2020) Saikat Dewanjee et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Closing the empty anti-Babesia gibsoni drug pipeline in vitro using fluorescence-based high throughput screening assay

(2020) Mohamed Abdo Rizk et al.   PARASITOLOGY INTERNATIONAL

The Pharmacological Activity, Biochemical Properties, and Pharmacokinetics of the Major Natural Polyphenolic Flavonoid: Quercetin

(2020) Gaber El-Saber Batiha et al.   Foods

Safety of Artemisinin Derivatives in the First Trimester of Pregnancy: A Controversial Story

(2020) Sarah D’Alessandro et al.   MOLECULES

Activities of artesunate-based combinations and tafenoquine against Babesia bovis in vitro and Babesia microti in vivo

(2020) Leonardo J. M. Carvalho et al.   Parasites & Vectors

Traditional application and modern pharmacological research of Artemisia annua L.

(2020) Xinchi Feng et al.   PHARMACOLOGY & THERAPEUTICS

Identification of Essential Oils Including Garlic Oil and Black Pepper Oil with High Activity against Babesia duncani

(2020) Yumin Zhang et al.   Pathogens

In vitro and in vivo growth inhibitory activities of cryptolepine hydrate against several Babesia species and Theileria equi

(2020) Gaber El-Saber Batiha et al.   PLoS Neglected Tropical Diseases

Bioactivity of dietary polyphenols: The role of metabolites

(2019) Simon Vlad Luca et al.   CRITICAL REVIEWS IN FOOD SCIENCE AND NUTRITION

Progress to Improve Oral Bioavailability and Beneficial Effects of Resveratrol

(2019) Adele Chimento et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Ellagic acid microspheres restrict the growth of Babesia and Theileria in vitro and Babesia microti in vivo

(2019) Amani Magdy Beshbishy et al.   Parasites & Vectors

Babesia microti—Borrelia Burgdorferi Coinfection

(2019) Nikhat Parveen et al.   Pathogens

Persistence of Babesia microti Infection in Humans

(2019) Evan M. Bloch et al.   Pathogens

Polymicrobial Nature of Tick-Borne Diseases

(2019) Santiago Sanchez-Vicente et al.   mBio

Combined effects of Scutellaria baicalensis with metformin on glucose tolerance of type 2 diabetes patients via gut microbiota modulation

(2019) Na Rae Shin et al.   AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM

The effect of supplementation with Scutellaria baicalensis on hepatic function

(2019) Basant K. Puri et al.   MEDICAL HYPOTHESES

Evaluation of in-vitro antimicrobial activity of Artemisia  apiacea H. and Scutellaria baicalensis G. extracts

(2018) Huan Trinh et al.   JOURNAL OF MEDICAL MICROBIOLOGY

Isobolographic analysis of co-administration of two plant-derived antiplasmodial drug candidates, cryptolepine and xylopic acid, in Plasmodium berghei

(2018) Elvis O. Ameyaw et al.   MALARIA JOURNAL

Drug resistance in Plasmodium

(2018) Kasturi Haldar et al.   NATURE REVIEWS MICROBIOLOGY

Insights into the evolution and drug susceptibility of Babesia duncani from the sequence of its mitochondrial and apicoplast genomes

(2018) Azan Z. Virji et al.   INTERNATIONAL JOURNAL FOR PARASITOLOGY

Inhibitory effects of fluoroquinolone antibiotics on Babesia divergens and Babesia microti, blood parasites of veterinary and zoonotic importance

(2018) Mohamed Abdo Rizk et al.   Infection and Drug Resistance

Evidence for transmission of the zoonotic apicomplexan parasite Babesia duncani by the tick Dermacentor albipictus

(2018) Andrea Swei et al.   INTERNATIONAL JOURNAL FOR PARASITOLOGY

Establishment of a continuous in vitro culture of Babesia duncani in human erythrocytes reveals unusually high tolerance to recommended therapies

(2018) Amanah Abraham et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Effect of Artemisia annua and Artemisia afra tea infusions on schistosomiasis in a large clinical trial

(2018) Jérôme Munyangi et al.   PHYTOMEDICINE

Artemisia annua and Artemisia afra tea infusions vs. artesunate-amodiaquine (ASAQ) in treating Plasmodium falciparum malaria in a large scale, double blind, randomized clinical trial

(2018) Jérôme Munyangi et al.   PHYTOMEDICINE

In vitro anti-malarial interaction and gametocytocidal activity of cryptolepine

(2017) Arnold Donkor Forkuo et al.   MALARIA JOURNAL

Artemisia annua dried leaf tablets treated malaria resistant to ACT and i.v. artesunate: Case reports

(2017) Nsengiyumva Bati Daddy et al.   PHYTOMEDICINE

Identification of cryptolepine metabolites in rat and human hepatocytes and metabolism and pharmacokinetics of cryptolepine in Sprague Dawley rats

(2017) Arnold Donkor Forkuo et al.   BMC Pharmacology & Toxicology

Effect of Artemisia annua extract on treating active rheumatoid arthritis: A randomized controlled trial

(2016) Min Yang et al.   Chinese Journal of Integrative Medicine

Multiple-Ascending-Dose Pharmacokinetics and Safety Evaluation of Baicalein Chewable Tablets in Healthy Chinese Volunteers

(2016) Hongxian Pang et al.   CLINICAL DRUG INVESTIGATION

Persistence of babesiosis for >2 years in a patient on rituximab for rheumatoid arthritis

(2016) John Raffalli et al.   DIAGNOSTIC MICROBIOLOGY AND INFECTIOUS DISEASE

Recent trends in phytochemistry, ethnobotany and pharmacological significance of Alchornea cordifolia (Schumach. & Thonn.) Muell. Arg.

(2016) Pone Kamdem Boniface et al.   JOURNAL OF ETHNOPHARMACOLOGY

Botanical drugs in Ayurveda and Traditional Chinese Medicine

(2016) Yogini Jaiswal et al.   JOURNAL OF ETHNOPHARMACOLOGY

Synergistic anti-malarial action of cryptolepine and artemisinins

(2016) Arnold D. Forkuo et al.   MALARIA JOURNAL

Emodin: A Review of its Pharmacology, Toxicity and Pharmacokinetics

(2016) Xiaoxv Dong et al.   PHYTOTHERAPY RESEARCH

Coinfection by Ixodes Tick-Borne Pathogens: Ecological, Epidemiological, and Clinical Consequences

(2016) Maria A. Diuk-Wasser et al.   TRENDS IN PARASITOLOGY

Efficacy of Scutellaria baicalensis for the Treatment of Hand, Foot, and Mouth Disease Associated with Encephalitis in Patients Infected with EV71: A Multicenter, Retrospective Analysis

(2016) Hailong Lin et al.   Biomed Research International

Synergistic Antibacterial Effects of Nanoparticles Encapsulated with Scutellaria baicalensis and Pure Chlorhexidine on Oral Bacterial Biofilms

(2016) Ken Leung et al.   Nanomaterials

Scutellaria baicalensis , the golden herb from the garden of Chinese medicinal plants

(2016) Qing Zhao et al.   Science Bulletin

Adverse Effects of Plant Food Supplements Self-Reported by Consumers in the PlantLIBRA Survey Involving Six European Countries

(2016) Patrizia Restani et al.   PLoS One

The Safety of Artemisinin Derivatives for the Treatment of Malaria in the 2nd or 3rd Trimester of Pregnancy: A Systematic Review and Meta-Analysis

(2016) Stephanie D. Kovacs et al.   PLoS One

Adverse effects of plant food supplements and botanical preparations: a systematic review with critical evaluation of causality

(2015) Chiara Di Lorenzo et al.   BRITISH JOURNAL OF CLINICAL PHARMACOLOGY

A pilot randomized, placebo-controlled clinical trial to investigate the efficacy and safety of an extract of Artemisia annua administered over 12 weeks, for managing pain, stiffness, and functional limitation associated with osteoarthritis of the hip and knee

(2015) Simon Stebbings et al.   CLINICAL RHEUMATOLOGY

Babesiosis

(2015) Edouard G. Vannier et al.   INFECTIOUS DISEASE CLINICS OF NORTH AMERICA

In vitroevaluation of antibacterial activity of phytochemicals and micronutrients againstBorrelia burgdorferiandBorrelia garinii

(2015) A. Goc et al.   JOURNAL OF APPLIED MICROBIOLOGY

The efficacy of artemisinin, artemether, and lumefantrine against Babesia gibsoni in vitro

(2015) Aiko Iguchi et al.   PARASITOLOGY INTERNATIONAL

Optimization of a Fluorescence-Based Assay for Large-Scale Drug Screening against Babesia and Theileria Parasites

(2015) Mohamed Abdo Rizk et al.   PLoS One

Dried whole-plantArtemisia annuaslows evolution of malaria drug resistance and overcomes resistance to artemisinin

(2015) Mostafa A. Elfawal et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Haem-activated promiscuous targeting of artemisinin in Plasmodium falciparum

(2015) Jigang Wang et al.   Nature Communications

Inhibitory effects of 19 antiprotozoal drugs and antibiotics on Babesia microti infection in BALB/c mice

(2015) Jun-ming Yao et al.   Journal of Infection in Developing Countries

Leishmanicidal Effect of Synthetic trans-Resveratrol Analogs

(2015) Carlos Luan Alves Passos et al.   PLoS One

Reproductive and toxic effects of methanol extract ofAlchornea cordifolialeaf in male rats

(2014) T. O. Ajibade et al.   ANDROLOGIA

Safety, tolerability, and pharmacokinetics of a single ascending dose of baicalein chewable tablets in healthy subjects

(2014) Min Li et al.   JOURNAL OF ETHNOPHARMACOLOGY

An Antiinflammatory and Reactive Oxygen Species Suppressive Effects of an Extract ofPolygonum CuspidatumContaining Resveratrol

(2014) Husam Ghanim et al.   MOLECULAR ENDOCRINOLOGY

Analgesic, Anti-Inflammatory, and Chondroprotective Activities ofCryptolepis buchananiExtract:In VitroandIn VivoStudies

(2014) Nutthiya Hanprasertpong et al.   Biomed Research International

Acute Liver Injury due to Flavocoxid (Limbrel), a Medical Food for Osteoarthritis

(2013) Naga Chalasani   ANNALS OF INTERNAL MEDICINE

Artemisone inhibits in vitro and in vivo propagation of Babesia bovis and B. bigemina parasites

(2013) Monica L. Mazuz et al.   EXPERIMENTAL PARASITOLOGY

Human Babesiosis

(2012) Edouard Vannier et al.   NEW ENGLAND JOURNAL OF MEDICINE

In vitro antimicrobial activity of ethanolic fractions of Cryptolepis sanguinolenta

(2012) Felix C Mills-Robertson et al.   Annals of Clinical Microbiology and Antimicrobials

Bioavailability of resveratrol

(2011) Thomas Walle   Annals of the New York Academy of Sciences

Novel Diamidines with Activity against Babesia divergensIn Vitroand Babesia microtiIn Vivo

(2011) Angela Nehrbass-Stuedli et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Study of the Chemical Composition and Antimicrobial Activities of Ethanolic Extracts from Roots of Scutellaria baicalensis Georgi

(2011) Yingjian Lu et al.   JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY

Whole plant extracts versus single compounds for the treatment of malaria: synergy and positive interactions

(2011) Philippe Rasoanaivo et al.   MALARIA JOURNAL

Antibacterial Activity, Bioavailability and Acute Toxicity Evaluation of the Leaf Extract of Alchornea cordifolia (Euphorbiaceae)

(2010) Donatien Gatsing et al.   International Journal of Pharmacology

Flavonoids from Artemisia annua L. as Antioxidants and Their Potential Synergism with Artemisinin against Malaria and Cancer

(2010) Jorge F.S. Ferreira et al.   MOLECULES

Artesunate, a potential drug for treatment of Babesia infection

(2010) Youn-Kyoung Goo et al.   PARASITOLOGY INTERNATIONAL

Antibacterial properties of Polygonum cuspidatum roots and their major bioactive constituents

(2008) Bin Shan et al.   FOOD CHEMISTRY

In vitro evaluation of the growth inhibitory activities of 15 drugs against Babesia gibsoni (Aomori strain)

(2008) Aya Matsuu et al.   VETERINARY PARASITOLOGY

Persistent and Relapsing Babesiosis in Immunocompromised Patients

(2007) P. J. Krause et al.   CLINICAL INFECTIOUS DISEASES

Antiprotozoal and cytotoxic screening of 45 plant extracts from Democratic Republic of Congo

(2007) G.K. Mesia et al.   JOURNAL OF ETHNOPHARMACOLOGY