AMPAkines potentiate the corticostriatal pathway to reduce acute and chronic pain

Sex-Specific Disruption of Distinct mPFC Inhibitory Neurons in Spared-Nerve Injury Model of Neuropathic Pain

(2020) Andrea F. Jones et al.   Cell Reports

A neuronal circuit for activating descending modulation of neuropathic pain

(2019) Junting Huang et al.   NATURE NEUROSCIENCE

Analgesic effects of optogenetic inhibition of basolateral amygdala inputs into the prefrontal cortex in nerve injured female mice

(2019) Vinicius M. Gadotti et al.   Molecular Brain

Altered Excitability and Local Connectivity of mPFC-PAG Neurons in a Mouse Model of Neuropathic Pain

(2018) John Cheriyan et al.   JOURNAL OF NEUROSCIENCE

Scaling Up Cortical Control Inhibits Pain

(2018) Jahrane Dale et al.   Cell Reports

Inhibition of the Prefrontal Projection to the Nucleus Accumbens Enhances Pain Sensitivity and Affect

(2018) Haocheng Zhou et al.   Frontiers in Cellular Neuroscience

Ketamine reduces aversion in rodent pain models by suppressing hyperactivity of the anterior cingulate cortex

(2018) Haocheng Zhou et al.   Nature Communications

The Dorsolateral Prefrontal Cortex in Acute and Chronic Pain

(2017) David A. Seminowicz et al.   JOURNAL OF PAIN

Corticostriatal Regulation of Acute Pain

(2017) Erik Martinez et al.   Frontiers in Cellular Neuroscience

AMPAkines Target the Nucleus Accumbens to Relieve Postoperative Pain

(2016) Chen Su et al.   ANESTHESIOLOGY

Rescue of Impaired mGluR5-Driven Endocannabinoid Signaling Restores Prefrontal Cortical Output to Inhibit Pain in Arthritic Rats

(2016) T. Kiritoshi et al.   JOURNAL OF NEUROSCIENCE

Post-anesthesia AMPA receptor potentiation prevents anesthesia-induced learning and synaptic deficits

(2016) Lianyan Huang et al.   Science Translational Medicine

Activation of Corticostriatal Circuitry Relieves Chronic Neuropathic Pain

(2015) M. Lee et al.   JOURNAL OF NEUROSCIENCE

Endogenous Opioid Activity in the Anterior Cingulate Cortex Is Required for Relief of Pain

(2015) E. Navratilova et al.   JOURNAL OF NEUROSCIENCE

Role of Prelimbic GABAergic Circuits in Sensory and Emotional Aspects of Neuropathic Pain

(2015) Zizhen Zhang et al.   Cell Reports

Persistent pain alters AMPA receptor subunit levels in the nucleus accumbens

(2015) Chen Su et al.   Molecular Brain

Editorial, supportive care and psychological issues around cancer

(2015) Elie Isenberg-Grzeda et al.   Current Opinion in Supportive and Palliative Care

AMPAkines Have Novel Analgesic Properties in Rat Models of Persistent Neuropathic and Inflammatory Pain

(2014) Alexander M. Le et al.   ANESTHESIOLOGY

Enhanced Medial Prefrontal-Default Mode Network Functional Connectivity in Chronic Pain and Its Association with Pain Rumination

(2014) A. Kucyi et al.   JOURNAL OF NEUROSCIENCE

Reward and motivation in pain and pain relief

(2014) Edita Navratilova et al.   NATURE NEUROSCIENCE

Decreased motivation during chronic pain requires long-term depression in the nucleus accumbens

(2014) N. Schwartz et al.   SCIENCE

Ketamine infusion for sickle cell pain crisis refractory to opioids: a case report and review of literature

(2013) Dipesh Uprety et al.   ANNALS OF HEMATOLOGY

Fast Left Prefrontal rTMS Reduces Post-Gastric Bypass Surgery Pain: Findings From a Large-Scale, Double-Blind, Sham-Controlled Clinical Trial

(2013) Jeffrey J. Borckardt et al.   Brain Stimulation

Calcium-Permeable AMPA Receptors in the Nucleus Accumbens Regulate Depression-Like Behaviors in the Chronic Neuropathic Pain State

(2013) Y. Goffer et al.   JOURNAL OF NEUROSCIENCE

The Role of a Low-Dose Ketamine-Midazolam Regimen in the Management of Severe Painful Crisis in Patients With Sickle Cell Disease

(2013) Qutaiba A. Tawfic et al.   JOURNAL OF PAIN AND SYMPTOM MANAGEMENT

Cognitive and emotional control of pain and its disruption in chronic pain

(2013) M. Catherine Bushnell et al.   NATURE REVIEWS NEUROSCIENCE

Corticostriatal functional connectivity predicts transition to chronic back pain

(2012) Marwan N Baliki et al.   NATURE NEUROSCIENCE

Neuromodulation of Thought: Flexibilities and Vulnerabilities in Prefrontal Cortical Network Synapses

(2012) Amy F.T. Arnsten et al.   NEURON

Pain relief produces negative reinforcement through activation of mesolimbic reward-valuation circuitry

(2012) E. Navratilova et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

A Single Subanesthetic Dose of Ketamine Relieves Depression-like Behaviors Induced by Neuropathic Pain in Rats

(2011) Jing Wang et al.   ANESTHESIOLOGY

Effects of the Putative Cognitive-Enhancing Ampakine, CX717, on Attention and Object Recognition Memory

(2011) Yiwen Zheng et al.   Current Alzheimer Research

Projection-Specific Modulation of Dopamine Neuron Synapses by Aversive and Rewarding Stimuli

(2011) Stephan Lammel et al.   NEURON

Emotion, Cognition, and Mental State Representation in Amygdala and Prefrontal Cortex

(2010) C. Daniel Salzman et al.   Annual Review of Neuroscience

Cognitive Impairment in Pain through Amygdala-Driven Prefrontal Cortical Deactivation

(2010) G. Ji et al.   JOURNAL OF NEUROSCIENCE

Contribution of chronic pain and neuroticism to abnormal forebrain gray matter in patients with temporomandibular disorder

(2010) Massieh Moayedi et al.   NEUROIMAGE

Predicting Value of Pain and Analgesia: Nucleus Accumbens Response to Noxious Stimuli Changes in the Presence of Chronic Pain

(2010) Marwan N. Baliki et al.   NEURON

Ampakine CX717 Protects against Fentanyl-induced Respiratory Depression and Lethal Apnea in Rats

(2009) Jun Ren et al.   ANESTHESIOLOGY

Positive modulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid (AMPA) receptors reverses sub-chronic PCP-induced deficits in the novel object recognition task in rats

(2009) Trine Damgaard et al.   BEHAVIOURAL BRAIN RESEARCH

Cellular and Molecular Mechanisms of Pain

(2009) Allan I. Basbaum et al.   CELL

Cortex and Memory: Emergence of a New Paradigm

(2009) Joaquín M. Fuster   JOURNAL OF COGNITIVE NEUROSCIENCE

Unmasking the tonic-aversive state in neuropathic pain

(2009) Tamara King et al.   NATURE NEUROSCIENCE

Cortico-Basal Ganglia Reward Network: Microcircuitry

(2009) Susan R Sesack et al.   NEUROPSYCHOPHARMACOLOGY

AMPA receptor subunit GluR1 downstream of D-1 dopamine receptor stimulation in nucleus accumbens shell mediates increased drug reward magnitude in food-restricted rats

(2009) K.D. Carr et al.   NEUROSCIENCE

Rostral ventral medulla cholinergic mechanism in pain-induced analgesia

(2009) Robert W. Gear et al.   NEUROSCIENCE LETTERS

Morphological and functional reorganization of rat medial prefrontal cortex in neuropathic pain

(2009) A. E. Metz et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Up-regulating BDNF with an ampakine rescues synaptic plasticity and memory in Huntington's disease knockin mice

(2009) D. A. Simmons et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Glutamate-based antidepressants: 20 years on

(2009) Phil Skolnick et al.   TRENDS IN PHARMACOLOGICAL SCIENCES

Signal valence in the nucleus accumbens to pain onset and offset

(2008) Lino Becerra et al.   EUROPEAN JOURNAL OF PAIN

Ampakine CX516 ameliorates functional deficits in AMPA receptors in a hippocampal slice model of protein accumulation

(2008) Patrick M. Kanju et al.   EXPERIMENTAL NEUROLOGY

Emotional environments retune the valence of appetitive versus fearful functions in nucleus accumbens

(2008) Sheila M Reynolds et al.   NATURE NEUROSCIENCE

The Brain in Chronic CRPS Pain: Abnormal Gray-White Matter Interactions in Emotional and Autonomic Regions

(2008) Paul Y. Geha et al.   NEURON