Endocrine Disruptors Acting on Estrogen and Androgen Pathways Cause Reproductive Disorders through Multiple Mechanisms: A Review

Endocrine Disruptors in Water and Their Effects on the Reproductive System

(2020) Andressa Gonsioroski et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Bisphenol A: an emerging threat to female fertility

(2020) Claudia Pivonello et al.   Reproductive Biology and Endocrinology

Germline-dependent transmission of male reproductive traits induced by an endocrine disruptor, di-2-ethylhexyl phthalate, in future generations

(2020) Radwa Barakat et al.   Scientific Reports

In utero exposure to low doses of genistein and di‐(2‐ethylhexyl) phthalate (DEHP) alters innate immune cells in neonatal and adult rat testes

(2020) Casandra Walker et al.   Andrology

Lifestyle, Oxidative Stress, and Antioxidants: Back and Forth in the Pathophysiology of Chronic Diseases

(2020) Mehdi Sharifi-Rad et al.   Frontiers in Physiology

Bisphenol A and Male Fertility: Myths and Realities

(2020) Chiara Castellini et al.   Frontiers in Endocrinology

Bisphenols Threaten Male Reproductive Health via Testicular Cells

(2020) Elikanah Olusayo Adegoke et al.   Frontiers in Endocrinology

Chronic exposure of BPA impairs male germ cell proliferation and induces lower sperm quality in male mice

(2020) XueXia Liu et al.   CHEMOSPHERE

The role of epigenetics in the reproductive toxicity of environmental endocrine disruptors

(2020) Yanbin Shi et al.   ENVIRONMENTAL AND MOLECULAR MUTAGENESIS

Heavy metal and pesticide levels in dairy products: Evaluation of human health risk

(2020) Valentin Năstăsescu et al.   FOOD AND CHEMICAL TOXICOLOGY

Female Fertility and Environmental Pollution

(2020) Rita Canipari et al.   International Journal of Environmental Research and Public Health

Water and soil pollution as determinant of water and food quality/contamination and its impact on male fertility

(2019) Andrea Di Nisio et al.   Reproductive Biology and Endocrinology

Prenatal exposure to bisphenol-A altered miRNA-224 and protein expression of aromatase in ovarian granulosa cells concomitant with elevated serum estradiol levels in F1 adult offspring

(2019) Christy Lite et al.   JOURNAL OF BIOCHEMICAL AND MOLECULAR TOXICOLOGY

The association of female and male infertility with telomere length (Review)

(2019) Eleni Vasilopoulos et al.   INTERNATIONAL JOURNAL OF MOLECULAR MEDICINE

Genotoxic, cytotoxic, and cytopathological effects in rats exposed for 18 months to a mixture of 13 chemicals in doses below NOAEL levels

(2019) Aristidis Tsatsakis et al.   TOXICOLOGY LETTERS

Endocrine-disrupting chemicals in aquatic environment: what are the risks for fish gametes?

(2018) Oliana Carnevali et al.   FISH PHYSIOLOGY AND BIOCHEMISTRY

Current Knowledge on Endocrine Disrupting Chemicals (EDCs) from Animal Biology to Humans, from Pregnancy to Adulthood: Highlights from a National Italian Meeting

(2018) Maria Street et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Association of pesticide exposure with human congenital abnormalities

(2018) Charikleia Kalliora et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY

Potential Health Risk of Endocrine Disruptors in Construction Sector and Plastics Industry: A New Paradigm in Occupational Health

(2018) Aleksandra Fucic et al.   International Journal of Environmental Research and Public Health

OUP accepted manuscript

(2018)   HUMAN REPRODUCTION UPDATE

Molecular and clinical aspects of embryotoxicity induced by acetylcholinesterase inhibitors

(2018) J. Tsiaoussis et al.   TOXICOLOGY

DNA Damage and Repair in Human Reproductive Cells

(2018) Anaís García-Rodríguez et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Pesticides Exposure by Air in Vineyard Rural Area and Respiratory Health in Children: A pilot study

(2018) C. Raherison et al.   ENVIRONMENTAL RESEARCH

Prenatal phthalate exposure and altered patterns of DNA methylation in cord blood

(2017) Olivia Solomon et al.   ENVIRONMENTAL AND MOLECULAR MUTAGENESIS

Human exposure to endocrine disrupting chemicals: effects on the male and female reproductive systems

(2017) Stavros Sifakis et al.   ENVIRONMENTAL TOXICOLOGY AND PHARMACOLOGY

Estrogen signaling, through estrogen receptor β, regulates DNA methylation and its machinery in male germ line in adult rats

(2017) Kushaan Dumasia et al.   Epigenetics

Obesity and female infertility: potential mediators of obesity's impact

(2017) Darcy E. Broughton et al.   FERTILITY AND STERILITY

Exposure to endocrine disruptors during adulthood: consequences for female fertility

(2017) Saniya Rattan et al.   JOURNAL OF ENDOCRINOLOGY

Occupational exposure to pesticides: time to nip it in the bud?

(2017) K Mortimer et al.   THORAX

Prenatal exposure to an environmentally relevant phthalate mixture disrupts reproduction in F1 female mice

(2017) Changqing Zhou et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY

An integrative transcriptomic analysis reveals bisphenol A exposure-induced dysregulation of microRNA expression in human endometrial cells

(2017) Wei-Chun Chou et al.   TOXICOLOGY IN VITRO

Agonistic and antagonistic effects of phthalates and their urinary metabolites on the steroid hormone receptors ERα, ERβ, and AR

(2017) Anika Engel et al.   TOXICOLOGY LETTERS

Seasonal trends in the prevalence of hypospadias: Aetiological implications

(2017) C. Mamoulakis et al.   Experimental and Therapeutic Medicine

Differential DNA methylation at conserved non-genic elements and evidence for transgenerational inheritance following developmental exposure to mono(2-ethylhexyl) phthalate and 5-azacytidine in zebrafish

(2017) Jorke H. Kamstra et al.   Epigenetics & Chromatin

Exposure to modern, widespread environmental endocrine disrupting chemicals and their effect on the reproductive potential of women: an overview of current epidemiological evidence

(2017) Anetta Karwacka et al.   Human Fertility

Low concentration of BPA induces mice spermatocytes apoptosis via GPR30

(2017) Chaoliang Wang et al.   Oncotarget

Endocrine Disruptors Leading to Obesity and Related Diseases

(2017) Demetrios Petrakis et al.   International Journal of Environmental Research and Public Health

Enhanced GSH synthesis by Bisphenol A exposure promoted DNA methylation process in the testes of adult rare minnow Gobiocypris rarus

(2016) Cong Yuan et al.   AQUATIC TOXICOLOGY

The role of estradiol in male reproductive function

(2016) Ranjith Ramasamy et al.   ASIAN JOURNAL OF ANDROLOGY

Dietary exposure to polychlorinated biphenyls and risk of breast, endometrial and ovarian cancer in a prospective cohort

(2016) Carolina Donat-Vargas et al.   BRITISH JOURNAL OF CANCER

Novel Epigenetic Biomarkers Mediating Bisphenol A Exposure and Metabolic Phenotypes in Female Mice

(2016) Olivia S. Anderson et al.   ENDOCRINOLOGY

A global assessment of phthalates burden and related links to health effects

(2016) Ioanna Katsikantami et al.   ENVIRONMENT INTERNATIONAL

Role of DNA methylation in bisphenol A exposed mouse spermatocyte

(2016) Li Yin et al.   ENVIRONMENTAL TOXICOLOGY AND PHARMACOLOGY

Bisphenol A causes reproductive toxicity, decreasesdnmt1transcription, and reduces global DNA methylation in breeding zebrafish(Danio rerio)

(2016) L. V. Laing et al.   Epigenetics

Detection of differential DNA methylation in repetitive DNA of mice and humans perinatally exposed to bisphenol A

(2016) Christopher Faulk et al.   Epigenetics

Endocrine-disrupting chemicals and uterine fibroids

(2016) Tiffany A. Katz et al.   FERTILITY AND STERILITY

Bisphenol A in soft drinks and canned foods and data evaluation

(2016) Manolis N. Tzatzarakis et al.   Food Additives & Contaminants Part B-Surveillance

MP70-16 THE MECHANISM OF ENVIRONMENTAL ENDOCRINE DISRUPTORS (DEHP) INDUCES EPIGENETIC TRANSGENERATIONAL INHERITANCE OF CRYPTORCHIDISM

(2016) Geng Xiong et al.   JOURNAL OF UROLOGY

Obesogens and male fertility

(2016) A. M. Cardoso et al.   Obesity Reviews

NMR WaterLOGSY Reveals Weak Binding of Bisphenol A with Amyloid Fibers of a Conserved 11 Residue Peptide from Androgen Receptor

(2016) Julia Asencio-Hernández et al.   PLoS One

Differential effects of bisphenol A and estradiol on rat spermatogenesis’ establishment

(2016) Vanessa Brouard et al.   REPRODUCTIVE TOXICOLOGY

DNA methylation in spermatogenesis and male infertility

(2016) Xiangrong Cui et al.   Experimental and Therapeutic Medicine

Comparison of the Effects of Dibutyl and Monobutyl Phthalates on the Steroidogenesis of Rat Immature Leydig Cells

(2016) Linxi Li et al.   Biomed Research International

In utero bisphenol A concentration, metabolism, and global DNA methylation across matched placenta, kidney, and liver in the human fetus

(2015) Muna S. Nahar et al.   CHEMOSPHERE

Male fertility following occupational exposure to dichlorodiphenyltrichloroethane (DDT)

(2015) Marcello Campagna et al.   ENVIRONMENT INTERNATIONAL

Sperm Aneuploidy in Faroese Men with Lifetime Exposure to Dichlorodiphenyldichloroethylene (p,p´-DDE) and Polychlorinated Biphenyl (PCB) Pollutants

(2015) Melissa J. Perry et al.   ENVIRONMENTAL HEALTH PERSPECTIVES

MicroRNAs as Potential Signatures of Environmental Exposure or Effect: A Systematic Review

(2015) Karen Vrijens et al.   ENVIRONMENTAL HEALTH PERSPECTIVES

Identification of SecretaglobinScgb2a1as a target for developmental reprogramming by BPA in the rat prostate

(2015) Rebecca Lee Yean Wong et al.   Epigenetics

Human ketosteroid receptors interact with hazardous phthalate plasticizers and their metabolites: anin silicostudy

(2015) M. K. Sarath Josh et al.   JOURNAL OF APPLIED TOXICOLOGY

In Utero Exposure to Phthalate Downregulates Critical Genes in Leydig Cells of F1Male Progeny

(2015) Suganya Sekaran et al.   JOURNAL OF CELLULAR BIOCHEMISTRY

Developmental exposure to bisphenol A alters expression and DNA methylation of Fkbp5, an important regulator of the stress response

(2015) Efthymia Kitraki et al.   MOLECULAR AND CELLULAR ENDOCRINOLOGY

Male-mediated F1 effects in mice exposed to bisphenol A, either alone or in combination with X-irradiation

(2015) Małgorzata M. Dobrzyńska et al.   MUTATION RESEARCH-GENETIC TOXICOLOGY AND ENVIRONMENTAL MUTAGENESIS

Androgen and Progesterone Receptors Are Targets for Bisphenol A (BPA), 4-Methyl-2,4-bis-(P-Hydroxyphenyl)Pent-1-Ene—A Potent Metabolite of BPA, and 4-Tert-Octylphenol: A Computational Insight

(2015) Mohd Rehan et al.   PLoS One

Chromosomal aneuploidies and DNA fragmentation of human spermatozoa from patients exposed to perfluorinated compounds

(2014) L. Governini et al.   ANDROLOGIA

Global and cyp19a1a gene specific DNA methylation in gonads of adult rare minnow Gobiocypris rarus under bisphenol A exposure

(2014) Yan Liu et al.   AQUATIC TOXICOLOGY

Persistent organic pollutants and male reproductive health

(2014) Anne Vested et al.   ASIAN JOURNAL OF ANDROLOGY

Perinatal bisphenol A exposure promotes dose-dependent alterations of the mouse methylome

(2014) Jung H Kim et al.   BMC GENOMICS

Embryonic PCB Exposure Alters Phenotypic, Genetic, and Epigenetic Profiles in Turtle Sex Determination, a Biomarker of Environmental Contamination

(2014) Yuiko Matsumoto et al.   ENDOCRINOLOGY

Bisphenol A (BPA) and its potential role in the pathogenesis of the polycystic ovary syndrome (PCOS)

(2014) Aleksandra Rutkowska et al.   GYNECOLOGICAL ENDOCRINOLOGY

Bisphenol-A and diethylstilbestrol exposure induces the expression of breast cancer associated long noncoding RNA HOTAIR in vitro and in vivo

(2014) Arunoday Bhan et al.   JOURNAL OF STEROID BIOCHEMISTRY AND MOLECULAR BIOLOGY

Bisphenol A induces oxidative stress-associated DNA damage in INS-1 cells

(2014) Fei Xin et al.   MUTATION RESEARCH-GENETIC TOXICOLOGY AND ENVIRONMENTAL MUTAGENESIS

Exposure to Low-Dose Bisphenol A Impairs Meiosis in the Rat Seminiferous Tubule Culture Model: A Physiotoxicogenomic Approach

(2014) Sazan Ali et al.   PLoS One

Pesticide Methoxychlor Promotes the Epigenetic Transgenerational Inheritance of Adult-Onset Disease through the Female Germline

(2014) Mohan Manikkam et al.   PLoS One

Prenatal Exposure to BPA Alters the Epigenome of the Rat Mammary Gland and Increases the Propensity to Neoplastic Development

(2014) Eugen Dhimolea et al.   PLoS One

Bisphenol A, oocyte maturation, implantation, and IVF outcome: review of animal and human data

(2014) Ronit Machtinger et al.   REPRODUCTIVE BIOMEDICINE ONLINE

Ioxynil and Tetrabromobisphenol A Suppress Thyroid-Hormone-Induced Activation of Transcriptional Elongation Mediated by Histone Modifications and RNA Polymerase II Phosphorylation

(2014) Syunsuke Otsuka et al.   TOXICOLOGICAL SCIENCES

Ancestral dichlorodiphenyltrichloroethane (DDT) exposure promotes epigenetic transgenerational inheritance of obesity

(2013) Michael K Skinner et al.   BMC Medicine

Hepatic DNA methylation modifications in early development of rats resulting from perinatal BPA exposure contribute to insulin resistance in adulthood

(2013) Y. Ma et al.   DIABETOLOGIA

Developmental Programming: Gestational Bisphenol-A Treatment Alters Trajectory of Fetal Ovarian Gene Expression

(2013) Almudena Veiga-Lopez et al.   ENDOCRINOLOGY

Androgen receptor activation by polychlorinated biphenyls

(2013) Lavinia Casati et al.   Epigenetics

Estrogen hormone physiology: Reproductive findings from estrogen receptor mutant mice

(2013) Katherine J. Hamilton et al.   Reproductive Biology

Environmental and occupational pesticide exposure and human sperm parameters: A systematic review

(2013) Sheena E. Martenies et al.   TOXICOLOGY

Computer-aided identification of novel protein targets of bisphenol A

(2013) Diana Montes-Grajales et al.   TOXICOLOGY LETTERS

Androgen receptor-mediated apoptosis in bovine testicular induced pluripotent stem cells in response to phthalate esters

(2013) S-W Wang et al.   Cell Death & Disease

Distinct mechanisms of endocrine disruption of DDT-related pesticides toward estrogen receptor α and estrogen-related receptor γ

(2012) Shulin Zhuang et al.   ENVIRONMENTAL TOXICOLOGY AND CHEMISTRY

Idiopathic recurrent miscarriage is caused mostly by aneuploid embryos

(2012) Brooke Hodes-Wertz et al.   FERTILITY AND STERILITY

Epigenetic Effects of Environmental Chemicals Bisphenol A and Phthalates

(2012) Sher Singh et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Environmental Estrogens Differentially Engage the Histone Methyltransferase EZH2 to Increase Risk of Uterine Tumorigenesis

(2012) K. L. Greathouse et al.   MOLECULAR CANCER RESEARCH

Endocrine Disruptor Regulation of MicroRNA Expression in Breast Carcinoma Cells

(2012) Syreeta L. Tilghman et al.   PLoS One

The role of micro-RNAs in the female reproductive tract

(2012) Warren B Nothnick   REPRODUCTION

Molecular docking, molecular dynamics simulation, and structure-based 3D-QSAR studies on estrogenic activity of hydroxylated polychlorinated biphenyls

(2012) Xiaolin Li et al.   SCIENCE OF THE TOTAL ENVIRONMENT

Persistent organochlorinated pesticides and mechanisms of their toxicity

(2012) Ezra J. Mrema et al.   TOXICOLOGY

Polychlorinated biphenyls affect histone modification pattern in early development of rats: a role for androgen receptor-dependent modulation?

(2012) Lavinia Casati et al.   Epigenomics

Altered Profile of Seminal Plasma MicroRNAs in the Molecular Diagnosis of Male Infertility

(2011) C. Wang et al.   CLINICAL CHEMISTRY

Environmental Exposure to Polychlorinated Biphenyls and p,p ´-DDE and Sperm Sex-Chromosome Disomy

(2011) Megan E. McAuliffe et al.   ENVIRONMENTAL HEALTH PERSPECTIVES

Bisphenol A: An endocrine disruptor with widespread exposure and multiple effects

(2011) Beverly S. Rubin   JOURNAL OF STEROID BIOCHEMISTRY AND MOLECULAR BIOLOGY

Polychlorinated biphenyl (PCB) exposure in mothers and time to pregnancy in daughters

(2011) Barbara A. Cohn et al.   REPRODUCTIVE TOXICOLOGY

Characterization of steroid hormone receptor activities in 100 hydroxylated polychlorinated biphenyls, including congeners identified in humans

(2011) Shinji Takeuchi et al.   TOXICOLOGY

Estrogen Receptor Mutations and Changes in Downstream Gene Expression and Signaling

(2010) I. Barone et al.   CLINICAL CANCER RESEARCH

Environmental factors and semen quality

(2010) Joanna Jurewicz et al.   International Journal of Occupational Medicine and Environmental Health

microRNAs in the Testis: Building Up Male Fertility

(2010) M. D. Papaioannou et al.   JOURNAL OF ANDROLOGY

Direct effects of diethylstilbestrol on the gene expression of the cholesterol side-chain cleavage enzyme (P450scc) in testicular Leydig cells

(2010) Katsuhiko Warita et al.   LIFE SCIENCES

Xenoestrogen-Induced Regulation of EZH2 and Histone Methylation via Estrogen Receptor Signaling to PI3K/AKT

(2010) Tiffany G. Bredfeldt et al.   MOLECULAR ENDOCRINOLOGY

Bisphenol A impairs the double-strand break repair machinery in the germline and causes chromosome abnormalities

(2010) P. Allard et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Bisphenol A exposure leads to specific microRNA alterations in placental cells

(2010) Michele Avissar-Whiting et al.   REPRODUCTIVE TOXICOLOGY

Exposure to Polychlorinated Biphenyls (PCBs) and Male Reproduction

(2010) John D. Meeker et al.   Systems Biology in Reproductive Medicine

Estrogen Regulation of MicroRNA Expression

(2009) Carolyn Klinge   CURRENT GENOMICS

Endocrine-Disrupting Chemicals: An Endocrine Society Scientific Statement

(2009) Evanthia Diamanti-Kandarakis et al.   ENDOCRINE REVIEWS

Maternal Pregnancy Levels of Polychlorinated Biphenyls and Risk of Hypospadias and Cryptorchidism in Male Offspring

(2009) Katherine A. McGlynn et al.   ENVIRONMENTAL HEALTH PERSPECTIVES

Low Doses of Bisphenol A Promote Human Seminoma Cell Proliferation by Activating PKA and PKG via a Membrane G-Protein–Coupled Estrogen Receptor

(2009) Adil Bouskine et al.   ENVIRONMENTAL HEALTH PERSPECTIVES

Determination of organochlorine pesticide and polychlorinated biphenyl levels in adipose tissue of infertile men

(2009) Ismet Çok et al.   ENVIRONMENTAL MONITORING AND ASSESSMENT

Negative effects of serum p,p′-DDE on sperm parameters and modification by genetic polymorphisms

(2009) Bridget M. Messaros et al.   ENVIRONMENTAL RESEARCH

Aneuploidy and DNA fragmentation in morphologically abnormal sperm

(2009) S. S. Tang et al.   INTERNATIONAL JOURNAL OF ANDROLOGY

Effects of Mixtures of Polychlorinated Biphenyls, Methylmercury, and Organochlorine Pesticides on Hepatic DNA Methylation in Prepubertal Female Sprague-Dawley Rats

(2009) Daniel Desaulniers et al.   INTERNATIONAL JOURNAL OF TOXICOLOGY

Oxidative DNA damage impairs global sperm DNA methylation in infertile men

(2009) Ozlem Tunc et al.   JOURNAL OF ASSISTED REPRODUCTION AND GENETICS

Linking DNA methylation and histone modification: patterns and paradigms

(2009) Howard Cedar et al.   NATURE REVIEWS GENETICS

Small RNA molecules in the regulation of spermatogenesis

(2009) Zuping He et al.   REPRODUCTION

Estrogenic and androgenic activity of PCBs, their chlorinated metabolites and other endocrine disruptors estimated with two in vitro yeast assays

(2009) K. Svobodová et al.   SCIENCE OF THE TOTAL ENVIRONMENT

Endocrine disruptors and estrogenic effects on male reproductive axis

(2008) Suresh C. Sikka et al.   ASIAN JOURNAL OF ANDROLOGY

Female reproductive disorders: the roles of endocrine-disrupting compounds and developmental timing

(2008) D. Andrew Crain et al.   FERTILITY AND STERILITY

Effects of p,p′ -DDE exposure on gonadal development and gene expression in Japanese medaka (Oryzias latipes)

(2008) Zhaobin ZHANG et al.   JOURNAL OF ENVIRONMENTAL SCIENCES

Fifteen Years after “Wingspread”—Environmental Endocrine Disrupters and Human and Wildlife Health: Where We are Today and Where We Need to Go

(2008) Andrew K. Hotchkiss et al.   TOXICOLOGICAL SCIENCES

Role for estradiol in female-typical brain and behavioral sexual differentiation

(2007) Julie Bakker et al.   FRONTIERS IN NEUROENDOCRINOLOGY