PDGFRb+ mesenchymal cells, but not NG2+ mural cells, contribute to cardiac fat

Parallel Lineage-Tracing Studies Establish Fibroblasts as the Prevailing In Vivo Adipocyte Progenitor

(2020) Paola Cattaneo et al.   Cell Reports

Mosaic Mutant Analysis Identifies PDGFRα/PDGFRβ as Negative Regulators of Adipogenesis

(2020) Chengyi Sun et al.   Cell Stem Cell

Perivascular Fibro-Adipogenic Progenitor Tracing during Post-Traumatic Osteoarthritis

(2020) Takashi Sono et al.   AMERICAN JOURNAL OF PATHOLOGY

Endocardial fibrosis complicated with a great amount of fat accumulation in subendocardium: a rare form of restrictive cardiomyopathy

(2019) Bin Wang et al.   EUROPEAN HEART JOURNAL

A Unique Collateral Artery Development Program Promotes Neonatal Heart Regeneration

(2019) Soumyashree Das et al.   CELL

Dual lineage tracing identifies intermediate mesenchymal stage for endocardial contribution to fibroblasts, coronary mural cells and adipocytes

(2019) Xinyan Huang et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Molecular mechanisms of arrhythmogenic cardiomyopathy

(2019) Karyn M. Austin et al.   Nature Reviews Cardiology

Involvement of pericardial adipose tissue in cardiac fibrosis of dietary-induced obese minipigs— Role of mitochondrial function

(2019) Sin-Jin Li et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS

Genetic Fate Mapping Defines the Vascular Potential of Endocardial Cells in the Adult HeartNovelty and Significance

(2018) Juan Tang et al.   CIRCULATION RESEARCH

The role of pericardial adipose tissue in the heart of obese minipigs

(2018) Chia-Yu Wang et al.   EUROPEAN JOURNAL OF CLINICAL INVESTIGATION

Neer Award 2018: Platelet-derived growth factor receptor α co-expression typifies a subset of platelet-derived growth factor receptor β–positive progenitor cells that contribute to fatty degeneration and fibrosis of the murine rotator cuff

(2018) Andrew R. Jensen et al.   JOURNAL OF SHOULDER AND ELBOW SURGERY

Single-Cell Transcriptional Profiling Reveals Cellular Diversity and Intercommunication in the Mouse Heart

(2018) Daniel A. Skelly et al.   Cell Reports

Single-Cell Deconvolution of Fibroblast Heterogeneity in Mouse Pulmonary Fibrosis

(2018) Ting Xie et al.   Cell Reports

Preexisting endothelial cells mediate cardiac neovascularization after injury

(2017) Lingjuan He et al.   JOURNAL OF CLINICAL INVESTIGATION

Evolutional change in epicardial fat and its correlation with myocardial diffuse fibrosis in heart failure patients

(2017) Cho-Kai Wu et al.   Journal of Clinical Lipidology

Generation of a whole-brain atlas for the cholinergic system and mesoscopic projectome analysis of basal forebrain cholinergic neurons

(2017) Xiangning Li et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Pdgfrβ+ Mural Preadipocytes Contribute to Adipocyte Hyperplasia Induced by High-Fat-Diet Feeding and Prolonged Cold Exposure in Adult Mice

(2016) Lavanya Vishvanath et al.   Cell Metabolism

Endothelial cells are progenitors of cardiac pericytes and vascular smooth muscle cells

(2016) Qi Chen et al.   Nature Communications

Genetic lineage tracing identifies in situ Kit-expressing cardiomyocytes

(2015) Qiaozhen Liu et al.   CELL RESEARCH

Perivascular Gli1+ Progenitors Are Key Contributors to Injury-Induced Organ Fibrosis

(2015) Rafael Kramann et al.   Cell Stem Cell

Adipocyte-Derived Hormone Leptin Is a Direct Regulator of Aldosterone Secretion, Which Promotes Endothelial Dysfunction and Cardiac FibrosisCLINICAL PERSPECTIVE

(2015) Anne-Cécile Huby et al.   CIRCULATION

Endocardium Contributes to Cardiac FatNovelty and Significance

(2015) Hui Zhang et al.   CIRCULATION RESEARCH

Cardiac mesenchymal stromal cells are a source of adipocytes in arrhythmogenic cardiomyopathy

(2015) E. Sommariva et al.   EUROPEAN HEART JOURNAL

PDGFRα signaling drives adipose tissue fibrosis by targeting progenitor cell plasticity

(2015) Tomoaki Iwayama et al.   GENES & DEVELOPMENT

Computed Tomographic Diagnosis of Myocardial Fat Deposits in Sarcoidosis

(2015) Farhood Saremi et al.   JOURNAL OF COMPUTER ASSISTED TOMOGRAPHY

Transgenic Mice for Intersectional Targeting of Neural Sensors and Effectors with High Specificity and Performance

(2015) Linda Madisen et al.   NEURON

Adipogenesis and epicardial adipose tissue: A novel fate of the epicardium induced by mesenchymal transformation and PPARγ activation

(2015) Yukiko Yamaguchi et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Embryonic attenuated Wnt/β-catenin signaling defines niche location and long-term stem cell fate in hair follicle

(2015) Zijian Xu et al.   eLife

Pericytes are progenitors for coronary artery smooth muscle

(2015) Katharina S Volz et al.   eLife

NG2 proteoglycan-dependent recruitment of tumor macrophages promotes pericyte-endothelial cell interactions required for brain tumor vascularization

(2015) Fusanori Yotsumoto et al.   OncoImmunology

Myocardial fat overgrowth in Proteus syndrome

(2014) H. Hannoush et al.   AMERICAN JOURNAL OF MEDICAL GENETICS PART A

A Smooth Muscle-Like Origin for Beige Adipocytes

(2014) Jonathan Z. Long et al.   Cell Metabolism

Epicardium-to-fat transition in injured heart

(2014) Qiaozhen Liu et al.   CELL RESEARCH

The Clinical Profile and Pathophysiology of Atrial Fibrillation

(2014) Jason Andrade et al.   CIRCULATION RESEARCH

Resident fibroblast lineages mediate pressure overload–induced cardiac fibrosis

(2014) Thomas Moore-Morris et al.   JOURNAL OF CLINICAL INVESTIGATION

Visceral and subcutaneous fat have different origins and evidence supports a mesothelial source

(2014) You-Ying Chau et al.   NATURE CELL BIOLOGY

The Expression of Relaxin-3 in Adipose Tissue and its Effects on Adipogenesis

(2014) Hiroyuki Yamamoto et al.   PROTEIN AND PEPTIDE LETTERS

Independent Stem Cell Lineages Regulate Adipose Organogenesis and Adipose Homeostasis

(2014) Yuwei Jiang et al.   Cell Reports

The role of focal adhesion kinase in BMP4 induction of mesenchymal stem cell adipogenesis

(2013) Jeong Soon Lee et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Intramyocardial Adiposity After Myocardial Infarction

(2013) Jim Pouliopoulos et al.   CIRCULATION

Connexin defects underlie arrhythmogenic right ventricular cardiomyopathy in a novel mouse model

(2013) Robert C. Lyon et al.   HUMAN MOLECULAR GENETICS

Role of Pericytes in Skeletal Muscle Regeneration and Fat Accumulation

(2013) Alexander Birbrair et al.   STEM CELLS AND DEVELOPMENT

Fat Deposition in Dilated Cardiomyopathy Assessed by CMR

(2013) Minjie Lu et al.   JACC-Cardiovascular Imaging

In Vivo Identification of Bipotential Adipocyte Progenitors Recruited by β3-Adrenoceptor Activation and High-Fat Feeding

(2012) Yun-Hee Lee et al.   Cell Metabolism

The Vascular Endothelium of the Adipose Tissue Gives Rise to Both White and Brown Fat Cells

(2012) Khanh-Van Tran et al.   Cell Metabolism

The role of cardiac fat in insulin resistance

(2012) Amalia Gastaldelli et al.   CURRENT OPINION IN CLINICAL NUTRITION AND METABOLIC CARE

Capillary and arteriolar pericytes attract innate leukocytes exiting through venules and 'instruct' them with pattern-recognition and motility programs

(2012) Konstantin Stark et al.   NATURE IMMUNOLOGY

Cytoskeletal and Focal Adhesion Influences on Mesenchymal Stem Cell Shape, Mechanical Properties, and Differentiation Down Osteogenic, Adipogenic, and Chondrogenic Pathways

(2012) Pattie S. Mathieu et al.   TISSUE ENGINEERING PART B-REVIEWS

Peri-adipocyte ECM remodeling in obesity and adipose tissue fibrosis

(2012) Tae-Hwa Chun   Adipocyte

Epicardial-Derived Cell Epithelial-to-Mesenchymal Transition and Fate Specification Require PDGF Receptor Signaling

(2011) Christopher L. Smith et al.   CIRCULATION RESEARCH

Pericytes: Developmental, Physiological, and Pathological Perspectives, Problems, and Promises

(2011) Annika Armulik et al.   DEVELOPMENTAL CELL

Fibrosis and adipogenesis originate from a common mesenchymal progenitor in skeletal muscle

(2011) A. Uezumi et al.   JOURNAL OF CELL SCIENCE

Adult mouse epicardium modulates myocardial injury by secreting paracrine factors

(2011) Bin Zhou et al.   JOURNAL OF CLINICAL INVESTIGATION

Mesenchymal progenitors distinct from satellite cells contribute to ectopic fat cell formation in skeletal muscle

(2010) Akiyoshi Uezumi et al.   NATURE CELL BIOLOGY

NG2+ CNS Glial Progenitors Remain Committed to the Oligodendrocyte Lineage in Postnatal Life and following Neurodegeneration

(2010) Shin H. Kang et al.   NEURON

Myocardial Fat at Cardiac Imaging: How Can We Differentiate Pathologic from Physiologic Fatty Infiltration?

(2010) Fumiko Kimura et al.   RADIOGRAPHICS

Dre recombinase, like Cre, is a highly efficient site-specific recombinase in E. coli, mammalian cells and mice

(2009) K. Anastassiadis et al.   Disease Models & Mechanisms

Arrhythmogenic right ventricular cardiomyopathy

(2009) Cristina Basso et al.   LANCET

A robust and high-throughput Cre reporting and characterization system for the whole mouse brain

(2009) Linda Madisen et al.   NATURE NEUROSCIENCE

Adiponectin Protects Against Angiotensin II–Induced Cardiac Fibrosis Through Activation of PPAR-α

(2008) Koichi Fujita et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

A Perivascular Origin for Mesenchymal Stem Cells in Multiple Human Organs

(2008) Mihaela Crisan et al.   Cell Stem Cell

Disruption of cell–matrix interactions by heparin enhances mesenchymal progenitor adipocyte differentiation

(2008) Weijun Luo et al.   EXPERIMENTAL CELL RESEARCH

White Fat Progenitor Cells Reside in the Adipose Vasculature

(2008) W. Tang et al.   SCIENCE