An mTORC1-dependent switch orchestrates the transition between mouse spermatogonial stem cells and clones of progenitor spermatogonia

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Unique Epigenetic Programming Distinguishes Regenerative Spermatogonial Stem Cells in the Developing Mouse Testis

(2020) Keren Cheng et al.   iScience

What has single-cell RNA-seq taught us about mammalian spermatogenesis?

(2019) Shinnosuke Suzuki et al.   BIOLOGY OF REPRODUCTION

Aging of spermatogonial stem cells by Jnk-mediated glycolysis activation

(2019) Mito Kanatsu-Shinohara et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Identification of EOMES-expressing spermatogonial stem cells and their regulation by PLZF

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Spatial transcriptome profiling by MERFISH reveals subcellular RNA compartmentalization and cell cycle-dependent gene expression

(2019) Chenglong Xia et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Cyclical expression of GDNF is required for spermatogonial stem cell homeostasis

(2018) Manju Sharma et al.   DEVELOPMENT

Identification of dynamic undifferentiated cell states within the male germline

(2018) Hue M. La et al.   Nature Communications

Characterization of germ cell differentiation in the male mouse through single-cell RNA sequencing

(2018) S. Lukassen et al.   Scientific Reports

Differences in Cell Cycle Status Underlie Transcriptional Heterogeneity in the HSC Compartment

(2018) Felicia Kathrine Bratt Lauridsen et al.   Cell Reports

IGF-Binding Proteins: Why Do They Exist and Why Are There So Many?

(2018) John B. Allard et al.   Frontiers in Endocrinology

GILZ-dependent modulation of mTORC1 regulates spermatogonial maintenance

(2018) Hue M. La et al.   DEVELOPMENT

A Comprehensive Roadmap of Murine Spermatogenesis Defined by Single-Cell RNA-Seq

(2018) Christopher Daniel Green et al.   DEVELOPMENTAL CELL

RNA velocity of single cells

(2018) Gioele La Manno et al.   NATURE

The adult human testis transcriptional cell atlas

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Competition for Mitogens Regulates Spermatogenic Stem Cell Homeostasis in an Open Niche

(2018) Yu Kitadate et al.   Cell Stem Cell

RNA Velocity: Molecular Kinetics from Single-Cell RNA-Seq

(2018) Valentine Svensson et al.   MOLECULAR CELL

Tutorial: guidelines for the experimental design of single-cell RNA sequencing studies

(2018) Atefeh Lafzi et al.   Nature Protocols

The Mammalian Spermatogenesis Single-Cell Transcriptome, from Spermatogonial Stem Cells to Spermatids

(2018) Brian P. Hermann et al.   Cell Reports

Single-Cell Transcriptomics Characterizes Cell Types in the Subventricular Zone and Uncovers Molecular Defects Impairing Adult Neurogenesis

(2018) Vera Zywitza et al.   Cell Reports

The Glial Cell-Derived Neurotrophic Factor (GDNF)-responsive Phosphoprotein Landscape Identifies Raptor Phosphorylation Required for Spermatogonial Progenitor Cell Proliferation

(2017) Min Wang et al.   MOLECULAR & CELLULAR PROTEOMICS

Periodic production of retinoic acid by meiotic and somatic cells coordinates four transitions in mouse spermatogenesis

(2017) Tsutomu Endo et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Massively parallel digital transcriptional profiling of single cells

(2017) Grace X. Y. Zheng et al.   Nature Communications

Glycolysis-Optimized Conditions Enhance Maintenance of Regenerative Integrity in Mouse Spermatogonial Stem Cells during Long-Term Culture

(2017) Aileen R. Helsel et al.   Stem Cell Reports

SHISA6 Confers Resistance to Differentiation-Promoting Wnt/β-Catenin Signaling in Mouse Spermatogenic Stem Cells

(2017) Moe Tokue et al.   Stem Cell Reports

In vivo dynamics of GFRα1-positive spermatogonia stimulated by GDNF signals using a bead transplantation assay

(2016) Aya Uchida et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

TSPAN8 Expression Distinguishes Spermatogonial Stem Cells in the Prepubertal Mouse Testis

(2016) K. Mutoji et al.   BIOLOGY OF REPRODUCTION

Enrichr: a comprehensive gene set enrichment analysis web server 2016 update

(2016) Maxim V. Kuleshov et al.   NUCLEIC ACIDS RESEARCH

Paracrine Wnt/β-catenin signaling mediates proliferation of undifferentiated spermatogonia in the adult mouse testis

(2016) Hinako M. Takase et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The Homeobox Transcription Factor RHOX10 Drives Mouse Spermatogonial Stem Cell Establishment

(2016) Hye-Won Song et al.   Cell Reports

Hierarchical differentiation competence in response to retinoic acid ensures stem cell maintenance during mouse spermatogenesis

(2015) K. Ikami et al.   DEVELOPMENT

Retinoic acid regulates Kit translation during spermatogonial differentiation in the mouse

(2015) Jonathan T. Busada et al.   DEVELOPMENTAL BIOLOGY

Mammalian target of rapamycin complex 1 (mTORC1) Is required for mouse spermatogonial differentiation in vivo

(2015) Jonathan T. Busada et al.   DEVELOPMENTAL BIOLOGY

Periodic retinoic acid–STRA8 signaling intersects with periodic germ-cell competencies to regulate spermatogenesis

(2015) Tsutomu Endo et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

IGF-1R Signaling Is Essential for the Proliferation of Cultured Mouse Spermatogonial Stem Cells by Promoting the G2/M Progression of the Cell Cycle

(2015) Si Wang et al.   STEM CELLS AND DEVELOPMENT

Id4 Marks Spermatogonial Stem Cells in the Mouse Testis

(2015) Feng Sun et al.   Scientific Reports

Functional Differences between GDNF-Dependent and FGF2-Dependent Mouse Spermatogonial Stem Cell Self-Renewal

(2015) Seiji Takashima et al.   Stem Cell Reports

Mouse Spermatogenic Stem Cells Continually Interconvert between Equipotent Singly Isolated and Syncytial States

(2014) Kenshiro Hara et al.   Cell Stem Cell

Functional and molecular features of the Id4+ germline stem cell population in mouse testes

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Quantitative Analysis of the Cellular Composition in Seminiferous Tubules in Normal and Genetically Modified Infertile Mice

(2014) Hiroki Nakata et al.   JOURNAL OF HISTOCHEMISTRY & CYTOCHEMISTRY

Enrichr: interactive and collaborative HTML5 gene list enrichment analysis tool

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TCC: an R package for comparing tag count data with robust normalization strategies

(2013) Jianqiang Sun et al.   BMC BIOINFORMATICS

FGF2 mediates mouse spermatogonial stem cell self-renewal via upregulation of Etv5 and Bcl6b through MAP2K1 activation

(2012) K. Ishii et al.   DEVELOPMENT

Retinoic acid induces Sertoli cell paracrine signals for spermatogonia differentiation but cell autonomously drives spermatocyte meiosis

(2012) M. Raverdeau et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Spermatogonia Differentiation Requires Retinoic Acid Receptor γ

(2011) Aurore Gely-Pernot et al.   ENDOCRINOLOGY

Distribution of GFRA1-expressing spermatogonia in adult mouse testis

(2011) Margherita Grasso et al.   REPRODUCTION

Plzf Regulates Germline Progenitor Self-Renewal by Opposing mTORC1

(2010) Robin M. Hobbs et al.   CELL

Functional Hierarchy and Reversibility Within the Murine Spermatogenic Stem Cell Compartment

(2010) T. Nakagawa et al.   SCIENCE

edgeR: a Bioconductor package for differential expression analysis of digital gene expression data

(2009) M. D. Robinson et al.   BIOINFORMATICS

Colony stimulating factor 1 is an extrinsic stimulator of mouse spermatogonial stem cell self-renewal

(2009) J. M. Oatley et al.   DEVELOPMENT

Molecular mechanisms of mTOR-mediated translational control

(2009) Xiaoju Max Ma et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Expression of Stimulated by Retinoic Acid Gene 8 (Stra8) and Maturation of Murine Gonocytes and Spermatogonia Induced by Retinoic Acid In Vitro1

(2007) Qing Zhou et al.   BIOLOGY OF REPRODUCTION