News Item
Multidisciplinary Sciences
Ariana Remmel
Summary: With the rollout of vaccines, researchers are gaining insights into the extent and nature of side effects.
Article
Immunology
Hang Song, Chan Zhao, Meifen Zhang
Summary: This retrospective study investigates the impact of inactivated COVID-19 vaccination on uveitis flare in patients. The results show that there is no significant difference in the flare rate of uveitis between the vaccination group and the control group within 30 days and 60 days after vaccination.
News Item
Multidisciplinary Sciences
Heidi Ledford
Summary: As much of the world struggles to access COVID-19 vaccines, there is a debate on whether to vaccinate children. While the UK has recommended delaying vaccines for most young people under 16, countries like the US and Israel have started vaccinating children, with others hoping to follow suit. Nature examines the evidence on children and COVID-19 vaccines.
Editorial Material
Biotechnology & Applied Microbiology
Asher Mullard
Summary: Oncologist and mRNA pioneer Ugur Sahin discusses his firm's development plans for cancer vaccines, mRNA-encoded proteins and more.
NATURE REVIEWS DRUG DISCOVERY
(2021)
Letter
Medicine, General & Internal
Peter W. W. Marks, Robert M. M. Califf, Paul A. A. Offit
Summary: The author of this letter criticizes Offit's viewpoint and presents evidence that shows the bivalent boosters have better immunogenicity against emerging variants. Therefore, the author suggests that the bivalent boosters should be deployed throughout the entire population, including against SARS-CoV-2 omicron subvariants BA.4 and BA.5 as well as the ancestral strain.
NEW ENGLAND JOURNAL OF MEDICINE
(2023)
Article
Medicine, General & Internal
Laurentina Schaler, Mary Wingfield
Summary: Studies show that COVID-19 vaccines do not affect future fertility, and pregnant women are at higher risk of complications from the virus, emphasizing the importance of vaccination for those planning a pregnancy. It is crucial to control the spread of misinformation regarding vaccine effects on fertility and ensure healthcare providers are well-informed on the topic.
IRISH JOURNAL OF MEDICAL SCIENCE
(2022)
Editorial Material
Medicine, General & Internal
Lawrence O. Gostin, Daniel A. Salmon, Heidi J. Larson
Summary: This Viewpoint discusses the possibility of US states, businesses, health care facilities, and schools and universities mandating coronavirus vaccination as a requirement for employment or service.
JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION
(2021)
Article
Immunology
Gang Chen, Xiaolin Li, Meixing Sun, Yangzhong Zhou, Meifang Yin, Bin Zhao, Xuemei Li
Summary: Prophylactic vaccination of COVID-19 mRNA vaccines is the first large-scale application of its kind in humans. Adverse events following immunization (AEFIs) were mostly non-severe local or systemic reactions. Allergy history may be a risk factor for anaphylaxis, while a history of anxiety could be linked to severe neurological AEs. These vaccine recipients require further evaluation and monitoring.
FRONTIERS IN IMMUNOLOGY
(2021)
Review
Biochemistry & Molecular Biology
Qinrui Huang, Jiawei Zeng, Jinghua Yan
Summary: The ongoing COVID-19 pandemic has accelerated the development of mRNA vaccines, with positive results reported and future challenges ahead.
JOURNAL OF GENETICS AND GENOMICS
(2021)
Review
Health Care Sciences & Services
Elena Satorres-Perez, Alicia Martinez-Varea, Jose Morales-Rosello
Summary: A systematic review found no significant association between COVID-19 vaccination and assisted reproductive techniques. Studies showed no differences in fertility treatment response, embryo quality, implantation rates, or pregnancy outcomes between vaccinated and unvaccinated patients. Therefore, COVID-19 vaccination is recommended for patients undergoing assisted reproductive techniques.
JOURNAL OF PERSONALIZED MEDICINE
(2023)
Review
Medicine, General & Internal
Dan H. Barouch
Summary: This article reviews the protective effects of vaccination and prior infection on severe Covid-19, and proposes future research directions.
NEW ENGLAND JOURNAL OF MEDICINE
(2022)
Review
Immunology
Javier Castrodeza-Sanz, Ivan Sanz-Munoz, Jose M. Eiros
Summary: In recent decades, improvements in traditional vaccines have led to the development of more processed vaccines with better tolerability profiles but lower immunogenicity. Adjuvants provide a good solution to enhance the immunogenicity of these vaccines with improved tolerability and fewer side effects. The approval of protein-based vaccines in 2022 and 2023 further expanded the options. Adjuvanted vaccines can induce potent immune responses in populations with weak or insufficient immune systems, such as the elderly, and could play a crucial role in completing global COVID-19 vaccination efforts in the present and future.
Article
Public, Environmental & Occupational Health
Sean M. Diament, Ayse Kaya, Ellen B. Magenheim
Summary: This study conducted a survey experiment to test different methods of increasing Americans' willingness to get vaccinated. The findings indicate that emphasizing the vaccine's approval process and the economic impact of the pandemic can significantly increase vaccination willingness. Additionally, the study suggests that the credibility of the message can influence its effectiveness.
SOCIAL SCIENCE & MEDICINE
(2022)
Article
Cardiac & Cardiovascular Systems
Biykem Bozkurt, Ishan Kamat, Peter J. Hotez
Summary: Myocarditis is a rare complication of COVID-19 mRNA vaccines, predominantly affecting young adult and adolescent males, with most patients showing improvement in symptoms. Possible mechanisms include molecular mimicry between viral proteins and self-antigens, dysregulated immune pathways, immune response to mRNA, and dysregulated cytokine expression.
Review
Obstetrics & Gynecology
Fei Chen, Shiheng Zhu, Zhiqing Dai, Lanting Hao, Chun Luan, Qi Guo, Chaofan Meng, Yankun Zhang
Summary: The COVID-19 pandemic has led to the rapid development and approval of multiple vaccines, including mRNA vaccines, which are considered ideal candidates. However, concerns about safety and efficacy have been raised, particularly regarding fertility. While current evidence is limited, studies suggest that COVID-19 mRNA vaccines do not have negative effects on fertility, even in pregnant women. Additional research, especially larger population-based studies, are needed to further assess the impact of vaccination on reproduction.
HUMAN REPRODUCTION
(2022)