RNA-seq and GSEA identifies suppression of ligand-gated chloride efflux channels as the major gene pathway contributing to form deprivation myopia

Reporting animal research: Explanation and elaboration for the ARRIVE guidelines 2.0

(2020) Nathalie Percie du Sert et al.   PLOS BIOLOGY

The Relation of Neutrophil to Lymphocyte Ratio and Platelet to Lymphocyte Ratio with High Axial Myopia

(2019) Erel Icel et al.   OCULAR IMMUNOLOGY AND INFLAMMATION

Lipid-gated monovalent ion fluxes regulate endocytic traffic and support immune surveillance

(2019) Spencer A. Freeman et al.   SCIENCE

Proteomic analysis of chick retina during early recovery from lens‑induced myopia

(2018) Yun Zhou et al.   Molecular Medicine Reports

Genome-wide association meta-analysis highlights light-induced signaling as a driver for refractive error

(2018) Milly S. Tedja et al.   NATURE GENETICS

Circadian rhythms, refractive development, and myopia

(2018) Ranjay Chakraborty et al.   OPHTHALMIC AND PHYSIOLOGICAL OPTICS

The increasing prevalence of myopia and high myopia among high school students in Fenghua city, eastern China: a 15-year population-based survey

(2018) Min Chen et al.   BMC Ophthalmology

CCDC102B confers risk of low vision and blindness in high myopia

(2018) Yoshikatsu Hosoda et al.   Nature Communications

Pathway analysis identifies altered mitochondrial metabolism, neurotransmission, structural pathways and complement cascade in retina/RPE/ choroid in chick model of form-deprivation myopia

(2018) Loretta Giummarra et al.   PeerJ

Short term optical defocus perturbs normal developmental shifts in retina/RPE protein abundance

(2018) Nina Riddell et al.   BMC DEVELOPMENTAL BIOLOGY

Gene expression in response to optical defocus of opposite signs reveals bidirectional mechanism of visually guided eye growth

(2018) Tatiana V. Tkatchenko et al.   PLOS BIOLOGY

The increasing prevalence of myopia in junior high school students in the Haidian District of Beijing, China: a 10-year population-based survey

(2017) Yan Li et al.   BMC Ophthalmology

Mitochondria-Derived Damage-Associated Molecular Patterns in Neurodegeneration

(2017) Heather M. Wilkins et al.   Frontiers in Immunology

Novel evidence for complement system activation in chick myopia and hyperopia models: a meta-analysis of transcriptome datasets

(2017) Nina Riddell et al.   Scientific Reports

Isotope-coded protein label based quantitative proteomic analysis reveals significant up-regulation of apolipoprotein A1 and ovotransferrin in the myopic chick vitreous

(2017) Feng-juan Yu et al.   Scientific Reports

Global Prevalence of Myopia and High Myopia and Temporal Trends from 2000 through 2050

(2016) Brien A. Holden et al.   OPHTHALMOLOGY

Differential Expression of Complement Markers in Normal and AMD Transmitochondrial Cybrids

(2016) Sonali Nashine et al.   PLoS One

Meta-analysis of gene–environment-wide association scans accounting for education level identifies additional loci for refractive error

(2016) Qiao Fan et al.   Nature Communications

Bidirectional Expression of Metabolic, Structural, and Immune Pathways in Early Myopia and Hyperopia

(2016) Nina Riddell et al.   Frontiers in Neuroscience

Large-Scale microRNA Expression Profiling Identifies Putative Retinal miRNA-mRNA Signaling Pathways Underlying Form-Deprivation Myopia in Mice

(2016) Andrei V. Tkatchenko et al.   PLoS One

Ion Channels in Innate and Adaptive Immunity

(2015) Stefan Feske et al.   Annual Review of Immunology

GOplot: an R package for visually combining expression data with functional analysis: Fig. 1.

(2015) Wencke Walter et al.   BIOINFORMATICS

Peripapillary Choroidal Thickness in Young Asians With High Myopia

(2015) P. Gupta et al.   INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE

The myopia boom

(2015) Elie Dolgin   NATURE

Regulation of cytoskeletal dynamics by redox signaling and oxidative stress: implications for neuronal development and trafficking

(2015) Carlos Wilson et al.   Frontiers in Cellular Neuroscience

Identification of myopia-associated WNT7B polymorphisms provides insights into the mechanism underlying the development of myopia

(2015) Masahiro Miyake et al.   Nature Communications

GABABReceptor Antagonist CGP46381 Inhibits Form-Deprivation Myopia Development in Guinea Pigs

(2015) Zhen-Ying Cheng et al.   Biomed Research International

Pathway Analysis: State of the Art

(2015) Miguel A. García-Campos et al.   Frontiers in Physiology

Trimmomatic: a flexible trimmer for Illumina sequence data

(2014) Anthony M. Bolger et al.   BIOINFORMATICS

Differential Retinal Protein Expressions During form Deprivation Myopia in Albino Guinea Pigs

(2014) Yi Wu et al.   Current Proteomics

Gene expression signatures in tree shrew choroid during lens-induced myopia and recovery

(2014) Li He et al.   EXPERIMENTAL EYE RESEARCH

Inhibition of form-deprivation myopia by a GABAAOr receptor antagonist, (1,2,5,6-tetrahydropyridin-4-yl) methylphosphinic acid (TPMPA), in guinea pigs

(2014) Zhen-Ying Cheng et al.   GRAEFES ARCHIVE FOR CLINICAL AND EXPERIMENTAL OPHTHALMOLOGY

Association of Mitochondrial Dysfunction with Oxidative Stress and Immune Suppression in Blunt Snout BreamMegalobrama amblycephalaFed a High-Fat Diet

(2014) Kang-Le Lu et al.   JOURNAL OF AQUATIC ANIMAL HEALTH

Anesthesia for Euthanasia Influences mRNA Expression in Healthy Mice and after Traumatic Brain Injury

(2014) Irina Staib-Lasarzik et al.   JOURNAL OF NEUROTRAUMA

Involvement of GABA Transporters in Atropine-Treated Myopic Retina As Revealed by iTRAQ Quantitative Proteomics

(2014) Veluchamy A. Barathi et al.   JOURNAL OF PROTEOME RESEARCH

Genome-Wide Meta-Analysis of Myopia and Hyperopia Provides Evidence for Replication of 11 Loci

(2014) Claire L. Simpson et al.   PLoS One

Nine Loci for Ocular Axial Length Identified through Genome-wide Association Studies, Including Shared Loci with Refractive Error

(2013) Ching-Yu Cheng et al.   AMERICAN JOURNAL OF HUMAN GENETICS

The effects and interactions of GABAergic and dopaminergic agents in the prevention of form deprivation myopia by brief periods of normal vision

(2013) Katrina L. Schmid et al.   EXPERIMENTAL EYE RESEARCH

Meta-analysis of genome-wide association studies in five cohorts reveals common variants in RBFOX1, a regulator of tissue-specific splicing, associated with refractive error

(2013) Dwight Stambolian et al.   HUMAN MOLECULAR GENETICS

A genome-wide meta-analysis identifies two novel loci associated with high myopia in the Han Chinese population

(2013) Y. Shi et al.   HUMAN MOLECULAR GENETICS

Genome-wide association study identifies ZFHX1B as a susceptibility locus for severe myopia

(2013) Chiea Chuen Khor et al.   HUMAN MOLECULAR GENETICS

Genome-wide meta-analyses of multiancestry cohorts identify multiple new susceptibility loci for refractive error and myopia

(2013) Virginie J M Verhoeven et al.   NATURE GENETICS

Identification of GABA receptors in chick retinal pigment epithelium

(2013) Zhen-Ying Cheng et al.   NEUROSCIENCE LETTERS

C-Reactive Protein and Complement Components in Patients with Pathological Myopia

(2013) Qin Long et al.   OPTOMETRY AND VISION SCIENCE

Genome-Wide Analysis Points to Roles for Extracellular Matrix Remodeling, the Visual Cycle, and Neuronal Development in Myopia

(2013) Amy K. Kiefer et al.   PLoS Genetics

TopHat2: accurate alignment of transcriptomes in the presence of insertions, deletions and gene fusions

(2013) Daehwan Kim et al.   GENOME BIOLOGY

Monocular myopic defocus and daily changes in axial length and choroidal thickness of human eyes

(2012) Ranjay Chakraborty et al.   EXPERIMENTAL EYE RESEARCH

Flicker downregulates the content of crystallin proteins in form-deprived C57BL/6 mouse retina

(2012) Saiqun Li et al.   EXPERIMENTAL EYE RESEARCH

Physiological Roles of Mitochondrial Reactive Oxygen Species

(2012) Laura A. Sena et al.   MOLECULAR CELL

Differential gene and transcript expression analysis of RNA-seq experiments with TopHat and Cufflinks

(2012) Cole Trapnell et al.   Nature Protocols

PANTHER in 2013: modeling the evolution of gene function, and other gene attributes, in the context of phylogenetic trees

(2012) Huaiyu Mi et al.   NUCLEIC ACIDS RESEARCH

Axial length and choroidal thickness changes accompanying prolonged accommodation in myopes and emmetropes

(2012) Emily C. Woodman et al.   VISION RESEARCH

Genetic Variants on Chromosome 1q41 Influence Ocular Axial Length and High Myopia

(2012) Qiao Fan et al.   PLoS Genetics

Genetic Variants at 13q12.12 Are Associated with High Myopia in the Han Chinese Population

(2011) Yi Shi et al.   AMERICAN JOURNAL OF HUMAN GENETICS

Molecular signatures database (MSigDB) 3.0

(2011) A. Liberzon et al.   BIOINFORMATICS

A genome-wide association study reveals association between common variants in an intergenic region of 4q25 and high-grade myopia in the Chinese Han population

(2011) Zhiqiang Li et al.   HUMAN MOLECULAR GENETICS

Influence of a Brief Episode of Anesthesia during the Induction of Experimental Brain Trauma on Secondary Brain Damage and Inflammation

(2011) Clara Luh et al.   PLoS One

The UBXN1 Protein Associates with Autoubiquitinated Forms of the BRCA1 Tumor Suppressor and Inhibits Its Enzymatic Function

(2010) Foon Wu-Baer et al.   MOLECULAR AND CELLULAR BIOLOGY

A genome-wide association study for myopia and refractive error identifies a susceptibility locus at 15q25

(2010) Pirro G Hysi et al.   NATURE GENETICS

A genome-wide association study identifies a susceptibility locus for refractive errors and myopia at 15q14

(2010) Abbas M Solouki et al.   NATURE GENETICS

Genome-Wide Association Studies Reveal Genetic Variants in CTNND2 for High Myopia in Singapore Chinese

(2010) Yi-Ju Li et al.   OPHTHALMOLOGY

edgeR: a Bioconductor package for differential expression analysis of digital gene expression data

(2009) M. D. Robinson et al.   BIOINFORMATICS

Identification of Myopia-Related Marker Proteins in Tilapia Retinal, RPE, and Choroidal Tissue following Induced Form Deprivation

(2009) Rasmus Jostrup et al.   CURRENT EYE RESEARCH

IL-4 induces protection of vascular endothelial cells against killing by complement and melittin through lipid biosynthesis

(2009) Sylvester M. Black et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Comparison of Automated Microarray Detection with Real-Time PCR Assays for Detection of Respiratory Viruses in Specimens Obtained from Children

(2009) F. Raymond et al.   JOURNAL OF CLINICAL MICROBIOLOGY

Bradykinin-induced astrocyte-neuron signalling: glutamate release is mediated by ROS-activated volume-sensitive outwardly rectifying anion channels

(2009) Hong-Tao Liu et al.   JOURNAL OF PHYSIOLOGY-LONDON

The multifunctional choroid

(2009) Debora L. Nickla et al.   PROGRESS IN RETINAL AND EYE RESEARCH

A Genome-Wide Association Analysis Identified a Novel Susceptible Locus for Pathological Myopia at 11q24.1

(2009) Hideo Nakanishi et al.   PLoS Genetics

Comparing Microarray Versus RT-PCR Assessment of Renal Allograft Biopsies: Similar Performance Despite Different Dynamic Ranges

(2008) K. Allanach et al.   AMERICAN JOURNAL OF TRANSPLANTATION

How mitochondria produce reactive oxygen species

(2008) Michael P. Murphy   BIOCHEMICAL JOURNAL

Cross-platform comparison of SYBR Green real-time PCR with TaqMan PCR, microarrays and other gene expression measurement technologies evaluated in the MicroArray Quality Control (MAQC) study

(2008) Emi Arikawa et al.   BMC GENOMICS

Novel, Potent, and Selective GABAC Antagonists Inhibit Myopia Development and Facilitate Learning and Memory

(2008) M. Chebib et al.   JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS

Potassium Channel and NKCC Cotransporter Involvement in Ocular Refractive Control Mechanisms

(2008) Sheila G. Crewther et al.   PLoS One