Passive immunotherapy targeting amyloid-β reduces cerebral amyloid angiopathy and improves vascular reactivity

Two Phase 3 Trials of Bapineuzumab in Mild-to-Moderate Alzheimer's Disease

(2014) Stephen Salloway et al.   NEW ENGLAND JOURNAL OF MEDICINE

The A4 Study: Stopping AD Before Symptoms Begin?

(2014) R. A. Sperling et al.   Science Translational Medicine

Safety and Pharmacology of a Single Intravenous Dose of Ponezumab in Subjects With Mild-to-Moderate Alzheimer Disease

(2013) Jaren W. Landen et al.   CLINICAL NEUROPHARMACOLOGY

In vivo measurement of apolipoprotein E from the brain interstitial fluid using microdialysis

(2013) Jason D Ulrich et al.   Molecular Neurodegeneration

Neurovascular decoupling is associated with severity of cerebral amyloid angiopathy

(2013) S. Peca et al.   NEUROLOGY

The Pathobiology of Vascular Dementia

(2013) Costantino Iadecola   NEURON

Functional magnetic resonance imaging detection of vascular reactivity in cerebral amyloid angiopathy

(2012) Andrew Dumas et al.   ANNALS OF NEUROLOGY

Chronic Administration of an Aglycosylated Murine Antibody of Ponezumab Does Not Worsen Microhemorrhages in Aged Tg2576 Mice

(2012) Gary B. Freeman et al.   Current Alzheimer Research

Amyloid-related imaging abnormalities in patients with Alzheimer's disease treated with bapineuzumab: a retrospective analysis

(2012) Reisa Sperling et al.   LANCET NEUROLOGY

Cerebrovascular lesions induce transient  -amyloid deposition

(2011) M. Garcia-Alloza et al.   BRAIN

Structural Basis of C-terminal β-Amyloid Peptide Binding by the Antibody Ponezumab for the Treatment of Alzheimer's Disease

(2011) Sherry L. La Porte et al.   JOURNAL OF MOLECULAR BIOLOGY

High throughput object-based image analysis of β-amyloid plaques in human and transgenic mouse brain

(2011) Harry D. Samaroo et al.   JOURNAL OF NEUROSCIENCE METHODS

Cerebral amyloid angiopathy pathology and cognitive domains in older persons

(2010) Zoe Arvanitakis et al.   ANNALS OF NEUROLOGY

Thinned-skull cranial window technique for long-term imaging of the cortex in live mice

(2010) Guang Yang et al.   Nature Protocols

11C-PIB binding is increased in patients with cerebral amyloid angiopathy-related hemorrhage

(2010) J. V. Ly et al.   NEUROLOGY

Decreased Clearance of CNS  -Amyloid in Alzheimer's Disease

(2010) K. G. Mawuenyega et al.   SCIENCE

Cerebrospinal fluid amyloid β40is decreased in cerebral amyloid angiopathy

(2009) Marcel M. Verbeek et al.   ANNALS OF NEUROLOGY

Silent ischemic infarcts are associated with hemorrhage burden in cerebral amyloid angiopathy

(2009) W. T. Kimberly et al.   NEUROLOGY

Two-photon imaging of dendritic spine development in the mouse cortex

(2008) Feng Pan et al.   Developmental Neurobiology

Cerebrovascular Dysfunction in Amyloid Precursor Protein Transgenic Mice: Contribution of Soluble and Insoluble Amyloid-  Peptide, Partial Restoration via  -Secretase Inhibition

(2008) B. H. Han et al.   JOURNAL OF NEUROSCIENCE

Impaired visual evoked flow velocity response in cerebral amyloid angiopathy

(2008) E. E. Smith et al.   NEUROLOGY

Solid-phase extraction enhances detection of beta-amyloid peptides in plasma and enables Aβ quantification following passive immunization with Aβ antibodies

(2007) Thomas A. Lanz et al.   JOURNAL OF NEUROSCIENCE METHODS