MR CLEAN-NO IV: intravenous treatment followed by endovascular treatment versus direct endovascular treatment for acute ischemic stroke caused by a proximal intracranial occlusion—study protocol for a randomized clinical trial

DEVT: A randomized, controlled, multicenter trial of direct endovascular treatment versus standard bridging therapy for acute stroke patients with large vessel occlusion in the anterior circulation – Protocol

(2020) Zhongming Qiu et al.   International Journal of Stroke

Endovascular Thrombectomy with or without Intravenous Alteplase in Acute Stroke

(2020) Pengfei Yang et al.   NEW ENGLAND JOURNAL OF MEDICINE

The randomized study of endovascular therapy with versus without intravenous tissue plasminogen activator in acute stroke with ICA and M1 occlusion (SKIP study)

(2019) Kentaro Suzuki et al.   International Journal of Stroke

Deferral of Consent in Acute Stroke Trials

(2019) Michel C.F. Shamy et al.   STROKE

Multicentre Randomised trial of Acute Stroke treatment in the Ambulance with a nitroglycerin Patch (MR ASAP): study protocol for a randomised controlled trial

(2019) Sophie A. van den Berg et al.   Trials

Thrombus Migration Paradox in Patients With Acute Ischemic Stroke

(2019) Heitor C. Alves et al.   STROKE

Neurological Deficits in Stroke Patients that May Impede the Capacity to Provide Informed Consent for Endovascular Treatment Trials

(2019) Paula M. Janssen et al.   Journal of Stroke & Cerebrovascular Diseases

Guidelines for the Early Management of Patients With Acute Ischemic Stroke: 2019 Update to the 2018 Guidelines for the Early Management of Acute Ischemic Stroke: A Guideline for Healthcare Professionals From the American Heart Association/American Stroke Association

(2019) William J. Powers et al.   STROKE

Direct mechanical thrombectomy in tPA-ineligible and -eligible patients versus the bridging approach: a meta-analysis

(2018) Johannes Kaesmacher et al.   Journal of NeuroInterventional Surgery

Comparative safety and efficacy of combined IVT and MT with direct MT in large vessel occlusion

(2018) Nitin Goyal et al.   NEUROLOGY

Tenecteplase versus Alteplase before Thrombectomy for Ischemic Stroke

(2018) Bruce C.V. Campbell et al.   NEW ENGLAND JOURNAL OF MEDICINE

Endovascular treatment for acute ischaemic stroke in routine clinical practice: prospective, observational cohort study (MR CLEAN Registry)

(2018) Ivo G H Jansen et al.   BMJ-British Medical Journal

Endovascular treatment for acute ischaemic stroke in routine clinical practice: prospective, observational cohort study (MR CLEAN Registry)

(2018) Ivo G H Jansen et al.   BMJ-British Medical Journal

Association of Clinical, Imaging, and Thrombus Characteristics With Recanalization of Visible Intracranial Occlusion in Patients With Acute Ischemic Stroke

(2018) Bijoy K. Menon et al.   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

Reader response: Comparative safety and efficacy of combined IVT and MT with direct MT in large vessel occlusion

(2018) Natalie E. LeCouffe et al.   NEUROLOGY

Two-Year Outcome after Endovascular Treatment for Acute Ischemic Stroke

(2017) Lucie A. van den Berg et al.   NEW ENGLAND JOURNAL OF MEDICINE

Comparison of Consent Models in a Randomized Trial of Corticosteroids in Pediatric Septic Shock*

(2017) Kusum Menon et al.   Pediatric Critical Care Medicine

Outcomes After Direct Thrombectomy or Combined Intravenous and Endovascular Treatment Are Not Different

(2017) Sònia Abilleira et al.   STROKE

Direct Mechanical Intervention Versus Bridging Therapy in Stroke Patients Eligible for Intravenous Thrombolysis

(2017) Sebastian Bellwald et al.   STROKE

Qualitative evaluation of a deferred consent process in paediatric emergency research: a PREDICT study

(2017) Jeremy Furyk et al.   BMJ Open

Combined Intravenous Thrombolysis and Thrombectomy vs Thrombectomy Alone for Acute Ischemic Stroke

(2017) Jonathan M. Coutinho et al.   JAMA Neurology

Does the use of IV tPA in the current era of rapid and predictable recanalization by mechanical embolectomy represent good value?: Table 1

(2016) Ronil V Chandra et al.   Journal of NeuroInterventional Surgery

Comparison of outcome and interventional complication rate in patients with acute stroke treated with mechanical thrombectomy with and without bridging thrombolysis

(2016) Ralph Weber et al.   Journal of NeuroInterventional Surgery

Endovascular thrombectomy after large-vessel ischaemic stroke: a meta-analysis of individual patient data from five randomised trials

(2016) Mayank Goyal et al.   LANCET

Mechanical thrombectomy after intravenous alteplase versus alteplase alone after stroke (THRACE): a randomised controlled trial

(2016) Serge Bracard et al.   LANCET NEUROLOGY

Direct Mechanical Intervention Versus Combined Intravenous and Mechanical Intervention in Large Artery Anterior Circulation Stroke

(2016) Anne Broeg-Morvay et al.   STROKE

Cost-Effectiveness of Endovascular Stroke Therapy

(2016) Wolfgang G. Kunz et al.   STROKE

The Deferred Consent Model in a Prospective Observational Study Evaluating Myocardial Injury in the Intensive Care Unit

(2016) Kimia Honarmand et al.   JOURNAL OF INTENSIVE CARE MEDICINE

Proposed methodology and classification of Infarct in New Territory (INT) after endovascular stroke treatment

(2015) Mayank Goyal et al.   Journal of NeuroInterventional Surgery

Thrombectomy within 8 Hours after Symptom Onset in Ischemic Stroke

(2015) Tudor G. Jovin et al.   NEW ENGLAND JOURNAL OF MEDICINE

Stent-Retriever Thrombectomy after Intravenous t-PA vs. t-PA Alone in Stroke

(2015) Jeffrey L. Saver et al.   NEW ENGLAND JOURNAL OF MEDICINE

Randomized Assessment of Rapid Endovascular Treatment of Ischemic Stroke

(2015) Mayank Goyal et al.   NEW ENGLAND JOURNAL OF MEDICINE

Endovascular Therapy for Ischemic Stroke with Perfusion-Imaging Selection

(2015) Bruce C.V. Campbell et al.   NEW ENGLAND JOURNAL OF MEDICINE

A Randomized Trial of Intraarterial Treatment for Acute Ischemic Stroke

(2015) Olvert A. Berkhemer et al.   NEW ENGLAND JOURNAL OF MEDICINE

Deferred Consent for Randomized Controlled Trials in Emergency Care Settings

(2015) K. Harron et al.   PEDIATRICS

Alteplase Reduces Downstream Microvascular Thrombosis and Improves the Benefit of Large Artery Recanalization in Stroke

(2015) Jean-Philippe Desilles et al.   STROKE

The Heidelberg Bleeding Classification

(2015) Rüdiger von Kummer et al.   STROKE

Prevalence and Outcomes of Symptomatic Intracranial Large Artery Stenoses and Occlusions in China

(2014) Yongjun Wang et al.   STROKE

MR CLEAN, a multicenter randomized clinical trial of endovascular treatment for acute ischemic stroke in the Netherlands: study protocol for a randomized controlled trial

(2014) Puck SS Fransen et al.   Trials

Automated Cerebral Infarct Volume Measurement in Follow-up Noncontrast CT Scans of Patients with Acute Ischemic Stroke

(2013) A.M. Boers et al.   AMERICAN JOURNAL OF NEURORADIOLOGY

How experience makes a difference: practitioners’ views on the use of deferred consent in paediatric and neonatal emergency care trials

(2013) Kerry Woolfall et al.   BMC Medical Ethics

2C or not 2C: defining an improved revascularization grading scale and the need for standardization of angiography outcomes in stroke trials

(2013) Mayank Goyal et al.   Journal of NeuroInterventional Surgery

Recommendations on Angiographic Revascularization Grading Standards for Acute Ischemic Stroke

(2013) Osama O. Zaidat et al.   STROKE

The Importance of Size

(2011) Christian H. Riedel et al.   STROKE

Covariate adjustment increases statistical power in randomized controlled trials

(2010) Hester Lingsma et al.   JOURNAL OF CLINICAL EPIDEMIOLOGY

Low Rates of Acute Recanalization With Intravenous Recombinant Tissue Plasminogen Activator in Ischemic Stroke

(2010) Rohit Bhatia et al.   STROKE