Arbiters of endogenous opioid analgesia: role of CNS estrogenic and glutamatergic systems

A Genetically Encoded Biosensor Reveals Location Bias of Opioid Drug Action

(2018) Miriam Stoeber et al.   NEURON

Pharmacological Modulation of Endogenous Opioid Activity to Attenuate Neuropathic Pain in Rats

(2018) Nai-Jiang Liu et al.   JOURNAL OF PAIN

Plasticity of Signaling by Spinal Estrogen Receptor α, κ-Opioid Receptor, and Metabotropic Glutamate Receptors over the Rat Reproductive Cycle Regulates Spinal Endomorphin 2 Antinociception: Relevance of Endogenous-Biased Agonism

(2017) Nai-Jiang Liu et al.   JOURNAL OF NEUROSCIENCE

Estrogens synthesized and acting within a spinal oligomer suppress spinal endomorphin 2 antinociception

(2017) Nai-Jiang Liu et al.   PAIN

Contribution of adrenomedullin to the switch of G protein-coupled μ-opioid receptors from Gi to Gs in the spinal dorsal horn following chronic morphine exposure in rats

(2016) Dongmei Wang et al.   BRITISH JOURNAL OF PHARMACOLOGY

Estrogens Suppress Spinal Endomorphin 2 Release in Female Rats in Phase with the Estrous Cycle

(2015) Arjun Kumar et al.   NEUROENDOCRINOLOGY

Establishing regional specificity of neuroestrogen action

(2014) Barney A. Schlinger et al.   GENERAL AND COMPARATIVE ENDOCRINOLOGY

Building up Analgesia in Humans via the Endogenous μ-Opioid System by Combining Placebo and Active tDCS: A Preliminary Report

(2014) Marcos F. DosSantos et al.   PLoS One

Decreased motivation during chronic pain requires long-term depression in the nucleus accumbens

(2014) N. Schwartz et al.   SCIENCE

Spinal Endomorphin 2 Antinociception and the Mechanisms That Produce It Are Both Sex- and Stage of Estrus Cycle–Dependent in Rats

(2013) Nai-Jiang Liu et al.   JOURNAL OF PAIN

Constitutive  -Opioid Receptor Activity Leads to Long-Term Endogenous Analgesia and Dependence

(2013) G. Corder et al.   SCIENCE

Estrogen Receptor β Activation Is Antinociceptive in a Model of Visceral Pain in the Rat

(2012) Dong-Yuan Cao et al.   JOURNAL OF PAIN

Endogenous opioids mediate left dorsolateral prefrontal cortex rTMS-induced analgesia

(2012) Joseph J. Taylor et al.   PAIN

Rapid Effects of Aggressive Interactions on Aromatase Activity and Oestradiol in Discrete Brain Regions of Wild Male White-Crowned Sparrows

(2011) T. D. Charlier et al.   JOURNAL OF NEUROENDOCRINOLOGY

Spinal Synthesis of Estrogen and Concomitant Signaling by Membrane Estrogen Receptors Regulate Spinal  - and  -Opioid Receptor Heterodimerization and Female-Specific Spinal Morphine Antinociception

(2011) N.-J. Liu et al.   JOURNAL OF NEUROSCIENCE

Spinal estrogen receptor alpha mediates estradiol-induced pronociception in a visceral pain model in the rat

(2011) Yaping Ji et al.   PAIN

Combined Liquid and Solid-Phase Extraction Improves Quantification of Brain Estrogen Content

(2011) Andrew Chao et al.   Frontiers in Neuroanatomy

Estrogen effects on pain sensitivity and neuropeptide expression in rat sensory neurons

(2010) Susan Sarajari et al.   EXPERIMENTAL NEUROLOGY

 -Opioid Receptors: Correlation of Agonist Efficacy for Signalling with Ability to Activate Internalization

(2010) J. McPherson et al.   MOLECULAR PHARMACOLOGY

Menstrual Variation in Experimental Pain: Correlation with Gonadal Hormones

(2010) M. Teepker et al.   NEUROPSYCHOBIOLOGY

Sex-specificity and estrogen-dependence of kappa opioid receptor-mediated antinociception and antihyperalgesia

(2010) Kera P. Lawson et al.   PAIN

Formation of  -/ -opioid receptor heterodimer is sex-dependent and mediates female-specific opioid analgesia

(2010) S. Chakrabarti et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Neuropathic and chronic pain stimuli downregulate central μ -opioid and dopaminergic transmission

(2010) Keiichi Niikura et al.   TRENDS IN PHARMACOLOGICAL SCIENCES

G Protein-Coupled Receptor 30: Estrogen Receptor or Collaborator?

(2009) Ellis R. Levin   ENDOCRINOLOGY

The Effects of Cycling Levels of 17β-Estradiol and Progesterone on the Magnitude of Temporomandibular Joint-Induced Nociception

(2009) P. R. Kramer et al.   ENDOCRINOLOGY

Estradiol and testosterone differently affect visceral pain-related behavioural responses in male and female rats

(2009) Anna Maria Aloisi et al.   EUROPEAN JOURNAL OF PAIN

Membrane estradiol signaling in the brain

(2009) Paul Micevych et al.   FRONTIERS IN NEUROENDOCRINOLOGY

Membrane-Localised Oestrogen Receptor α and β Influence Neuronal Activity Through Activation of Metabotropic Glutamate Receptors

(2009) P. G. Mermelstein   JOURNAL OF NEUROENDOCRINOLOGY

Brain Gray Matter Decrease in Chronic Pain Is the Consequence and Not the Cause of Pain

(2009) R. Rodriguez-Raecke et al.   JOURNAL OF NEUROSCIENCE

Sex, Gender, and Pain: A Review of Recent Clinical and Experimental Findings

(2009) Roger B. Fillingim et al.   JOURNAL OF PAIN

17 -Estradiol Mediates the Sex Difference in Capsaicin-Induced Nociception in Rats

(2009) Y.-C. Lu et al.   JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS

Ablation of estrogen receptor α or β eliminates sex differences in mechanical pain threshold in normal and inflamed mice

(2009) Lili Li et al.   PAIN

Beyond Feeling: Chronic Pain Hurts the Brain, Disrupting the Default-Mode Network Dynamics

(2008) M. N. Baliki et al.   JOURNAL OF NEUROSCIENCE

The Influence of Sex and Ovarian Hormones on Temporomandibular Joint Nociception in Rats

(2008) Luana Fischer et al.   JOURNAL OF PAIN

Forebrain steroid levels fluctuate rapidly during social interactions

(2008) Luke Remage-Healey et al.   NATURE NEUROSCIENCE

Non-genomic actions of estrogens and their interaction with genomic actions in the brain

(2007) Nandini Vasudevan et al.   FRONTIERS IN NEUROENDOCRINOLOGY