Mini review: genome and transcriptome editing using CRISPR-cas systems for haematological malignancy gene therapy

CRISPR-engineered T cells in patients with refractory cancer

(2020) Edward A. Stadtmauer et al.   SCIENCE

Identification of preexisting adaptive immunity to Cas9 proteins in humans

(2019) Carsten T. Charlesworth et al.   NATURE MEDICINE

CRISPR to fix bad blood: a new tool in basic and clinical hematology

(2019) Elisa González-Romero et al.   HAEMATOLOGICA

Hematopoietic Stem Cell Transplant for the Treatment of X-MAID

(2019) Sarah E. Henrickson et al.   Frontiers in Pediatrics

Improving homology-directed repair efficiency in human stem cells

(2019) William C. Skarnes et al.   METHODS

Search-and-replace genome editing without double-strand breaks or donor DNA

(2019) Andrew V. Anzalone et al.   NATURE

CRISPR base editors: genome editing without double-stranded breaks

(2018) Ayman Eid et al.   BIOCHEMICAL JOURNAL

Genetics of diffuse large B-cell lymphoma

(2018) Laura Pasqualucci et al.   BLOOD

Transcriptome Engineering with RNA-Targeting Type VI-D CRISPR Effectors

(2018) Silvana Konermann et al.   CELL

Applications and advances of CRISPR-Cas9 in cancer immunotherapy

(2018) An-Liang Xia et al.   JOURNAL OF MEDICAL GENETICS

An “off-the-shelf” fratricide-resistant CAR-T for the treatment of T cell hematologic malignancies

(2018) Matthew L Cooper et al.   LEUKEMIA

Field-deployable viral diagnostics using CRISPR-Cas13

(2018) Cameron Myhrvold et al.   SCIENCE

Multiplexed and portable nucleic acid detection platform with Cas13, Cas12a, and Csm6

(2018) Jonathan S. Gootenberg et al.   SCIENCE

Development of an integrated CRISPRi targeting ΔNp63 for treatment of squamous cell carcinoma

(2018) Masakazu Yoshida et al.   Oncotarget

Priming Human Repopulating Hematopoietic Stem and Progenitor Cells for Cas9/sgRNA Gene Targeting

(2018) Carsten T. Charlesworth et al.   Molecular Therapy-Nucleic Acids

Exome Sequencing Diagnoses X-Linked Moesin-Associated Immunodeficiency in a Primary Immunodeficiency Case

(2018) Gabrielle Bradshaw et al.   Frontiers in Immunology

CRISPR/Cas9 genome editing: Fueling the revolution in cancer immunotherapy

(2018) Xiaojun Liu et al.   Current Research in Translational Medicine

Activating PTEN Tumor Suppressor Expression with the CRISPR/dCas9 System

(2018) Colette Moses et al.   Molecular Therapy-Nucleic Acids

RNA Targeting by Functionally Orthogonal Type VI-A CRISPR-Cas Enzymes

(2017) Alexandra East-Seletsky et al.   MOLECULAR CELL

RNA targeting with CRISPR–Cas13

(2017) Omar O. Abudayyeh et al.   NATURE

RNA editing with CRISPR-Cas13

(2017) David B. T. Cox et al.   SCIENCE

Immunity to CRISPR Cas9 and Cas12a therapeutics

(2017) Wei Leong Chew   Wiley Interdisciplinary Reviews-Systems Biology and Medicine

Advances in the delivery of RNA therapeutics: from concept to clinical reality

(2017) James C. Kaczmarek et al.   Genome Medicine

Ethical and regulatory aspects of genome editing

(2016) Donald B. Kohn et al.   BLOOD

Programmable RNA Tracking in Live Cells with CRISPR/Cas9

(2016) David A. Nelles et al.   CELL

Multiplex Genome Editing to Generate Universal CAR T Cells Resistant to PD1 Inhibition

(2016) Jiangtao Ren et al.   CLINICAL CANCER RESEARCH

X-linked primary immunodeficiency associated with hemizygous mutations in the moesin ( MSN ) gene

(2016) Chantal Lagresle-Peyrou et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Programmable editing of a target base in genomic DNA without double-stranded DNA cleavage

(2016) Alexis C. Komor et al.   NATURE

Genomic Classification and Prognosis in Acute Myeloid Leukemia

(2016) Elli Papaemmanuil et al.   NEW ENGLAND JOURNAL OF MEDICINE

An efficient system for selectively altering genetic information within mRNAs

(2016) Maria Fernanda Montiel-González et al.   NUCLEIC ACIDS RESEARCH

C2c2 is a single-component programmable RNA-guided RNA-targeting CRISPR effector

(2016) Omar O. Abudayyeh et al.   SCIENCE

CRISPR-Cas9-mediated disruption of PD-1 on human T cells for adoptive cellular therapies of EBV positive gastric cancer

(2016) Shu Su et al.   OncoImmunology

Applications of Cas9 as an RNA-programmed RNA-binding protein

(2015) David A. Nelles et al.   BIOESSAYS

Engineering Complex Synthetic Transcriptional Programs with CRISPR RNA Scaffolds

(2015) Jesse G. Zalatan et al.   CELL

Potential pitfalls of CRISPR/Cas9-mediated genome editing

(2015) Rongxue Peng et al.   FEBS Journal

DNase H Activity of Neisseria meningitidis Cas9

(2015) Yan Zhang et al.   MOLECULAR CELL

CRISPR/Cas9 for genome editing: progress, implications and challenges

(2014) F. Zhang et al.   HUMAN MOLECULAR GENETICS

Programmable RNA recognition and cleavage by CRISPR/Cas9

(2014) Mitchell R. O’Connell et al.   NATURE

Efficient genome modification by CRISPR-Cas9 nickase with minimal off-target effects

(2014) Bin Shen et al.   NATURE METHODS

The new frontier of genome engineering with CRISPR-Cas9

(2014) J. A. Doudna et al.   SCIENCE

Enhanced homology-directed human genome engineering by controlled timing of CRISPR/Cas9 delivery

(2014) Steven Lin et al.   eLife

Multiplexed activation of endogenous genes by CRISPR-on, an RNA-guided transcriptional activator system

(2013) Albert W Cheng et al.   CELL RESEARCH

Genome engineering using the CRISPR-Cas9 system

(2013) F Ann Ran et al.   Nature Protocols

Multiplex Genome Engineering Using CRISPR/Cas Systems

(2013) L. Cong et al.   SCIENCE

RNA-dependent DNA endonuclease Cas9 of the CRISPR system: Holy Grail of genome editing?

(2013) Giedrius Gasiunas et al.   TRENDS IN MICROBIOLOGY

CRISPR-Cas systems target a diverse collection of invasive mobile genetic elements in human microbiomes

(2013) Quan Zhang et al.   GENOME BIOLOGY

Cas9-crRNA ribonucleoprotein complex mediates specific DNA cleavage for adaptive immunity in bacteria

(2012) G. Gasiunas et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

A Programmable Dual-RNA-Guided DNA Endonuclease in Adaptive Bacterial Immunity

(2012) M. Jinek et al.   SCIENCE

CRISPR-Cas Systems in Bacteria and Archaea: Versatile Small RNAs for Adaptive Defense and Regulation

(2011) Devaki Bhaya et al.   Annual Review of Genetics