A direct peptide reactivity assay using a high-throughput mass spectrometry screening platform for detection of skin sensitizers

Physiologically relevant orthogonal assays for the discovery of small-molecule modulators of WIP1 phosphatase in high-throughput screens

(2019) Victor Clausse et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

High-throughput screening (HTS)-based spectrophotometric direct peptide reactivity assay (Spectro-DPRA) to predict human skin sensitization potential

(2019) Sun-A Cho et al.   TOXICOLOGY LETTERS

A highly sensitive and selective high pressure liquid chromatography with tandem mass spectrometry (HPLC/MS-MS) method for the direct peptide reactivity assay (DPRA)

(2018) Fagen Zhang et al.   JOURNAL OF PHARMACOLOGICAL AND TOXICOLOGICAL METHODS

Prediction of skin sensitization potency sub-categories using peptide reactivity data

(2017) Britta Wareing et al.   TOXICOLOGY IN VITRO

Development of a RapidFire mass spectrometry assay and a fluorescence assay for the discovery of kynurenine aminotransferase II inhibitors to treat central nervous system disorders

(2016) Hao Lu et al.   ANALYTICAL BIOCHEMISTRY

Assessment of Pre- and Pro-haptens Using Nonanimal Test Methods for Skin Sensitization

(2016) Daniel Urbisch et al.   CHEMICAL RESEARCH IN TOXICOLOGY

A novelin chemicomethod to detect skin sensitizers in highly diluted reaction conditions

(2015) Yusuke Yamamoto et al.   JOURNAL OF APPLIED TOXICOLOGY

Applying Adverse Outcome Pathways (AOPs) to support Integrated Approaches to Testing and Assessment (IATA)

(2014) Knut Erik Tollefsen et al.   REGULATORY TOXICOLOGY AND PHARMACOLOGY

Skin sensitisation – Moving forward with non-animal testing strategies for regulatory purposes in the EU

(2013) David Basketter et al.   REGULATORY TOXICOLOGY AND PHARMACOLOGY

Method for detecting the reactivity of chemicals towards peptides as an alternative test method for assessing skin sensitization potential

(2013) Sun-A. Cho et al.   TOXICOLOGY LETTERS

Screening for lysine-specific demethylase-1 inhibitors using a label-free high-throughput mass spectrometry assay

(2011) Matthew Plant et al.   ANALYTICAL BIOCHEMISTRY

High Throughput Kinetic Profiling Approach for Covalent Binding to Peptides: Application to Skin Sensitization Potency of Michael Acceptor Electrophiles

(2009) David W. Roberts et al.   CHEMICAL RESEARCH IN TOXICOLOGY

Methyldibromoglutaronitrile: skin sensitization and quantitative risk assessment

(2009) David A. Basketter   Cutaneous and Ocular Toxicology

Investigation of Peptide Reactivity of Pro-hapten Skin Sensitizers Using a Peroxidase-Peroxide Oxidation System

(2009) G. Frank Gerberick et al.   TOXICOLOGICAL SCIENCES

LC-MS–Based Characterization of the Peptide Reactivity of Chemicals to Improve the In Vitro Prediction of the Skin Sensitization Potential

(2008) Andreas Natsch et al.   TOXICOLOGICAL SCIENCES

Skin sensitization in chemical risk assessment: Report of a WHO/IPCS international workshop focusing on dose–response assessment

(2007) Henk van Loveren et al.   REGULATORY TOXICOLOGY AND PHARMACOLOGY