Ultrasensitive electrochemical assay for microRNA-21 based on CRISPR/Cas13a-assisted catalytic hairpin assembly

Universal and Naked-Eye Gene Detection Platform Based on the Clustered Regularly Interspaced Short Palindromic Repeats/Cas12a/13a System

(2020) Chaoqun Yuan et al.   ANALYTICAL CHEMISTRY

Electrochemical Sensing of Exosomal MicroRNA Based on Hybridization Chain Reaction Signal Amplification with Reduced False-Positive Signals

(2020) Qunqun Guo et al.   ANALYTICAL CHEMISTRY

Rapid and Fully Microfluidic Ebola Virus Detection with CRISPR-Cas13a

(2019) Peiwu Qin et al.   ACS Sensors

CRISPR/Cas13a Signal Amplification Linked Immunosorbent Assay for Femtomolar Protein Detection

(2019) Qian Chen et al.   ANALYTICAL CHEMISTRY

Peptide nucleic acid-based electrochemical biosensor for simultaneous detection of multiple microRNAs from cancer cells with catalytic hairpin assembly amplification

(2019) Pan Fu et al.   SENSORS AND ACTUATORS B-CHEMICAL

A new photoelectrochemical biosensor for ultrasensitive determination of nucleic acids based on a three-stage cascade signal amplification strategy

(2018) Erhu Xiong et al.   ANALYST

Clustered Regularly Interspaced Short Palindromic Repeats/Cas9 Triggered Isothermal Amplification for Site-Specific Nucleic Acid Detection

(2018) Mengqi Huang et al.   ANALYTICAL CHEMISTRY

Reduced graphene oxide/BiFeO 3 nanohybrids-based signal-on photoelectrochemical sensing system for prostate-specific antigen detection coupling with magnetic microfluidic device

(2018) Qian Zhou et al.   BIOSENSORS & BIOELECTRONICS

CRISPR-Cas12a has both cis- and trans-cleavage activities on single-stranded DNA

(2018) Shi-Yuan Li et al.   CELL RESEARCH

Field-deployable viral diagnostics using CRISPR-Cas13

(2018) Cameron Myhrvold et al.   SCIENCE

CRISPR-Cas12a target binding unleashes indiscriminate single-stranded DNase activity

(2018) Janice S. Chen et al.   SCIENCE

Next-generation diagnostics with CRISPR

(2018) Daniel S. Chertow   SCIENCE

Multiplexed and portable nucleic acid detection platform with Cas13, Cas12a, and Csm6

(2018) Jonathan S. Gootenberg et al.   SCIENCE

Highly Effective and Low-Cost MicroRNA Detection with CRISPR-Cas9

(2018) Xin-Yuan Qiu et al.   ACS Synthetic Biology

Direct Visualization of Single-Nucleotide Variation in mtDNA Using a CRISPR/Cas9-Mediated Proximity Ligation Assay

(2018) Kaixiang Zhang et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Programmed DNA destruction by miniature CRISPR-Cas14 enzymes

(2018) Lucas B. Harrington et al.   SCIENCE

An electrochemical biosensor for highly sensitive detection of microRNA-377 based on strand displacement amplification coupled with three-way junction

(2017) Rong Hu et al.   JOURNAL OF ELECTROANALYTICAL CHEMISTRY

Fingerprints of Modified RNA Bases from Deep Sequencing Profiles

(2017) Anna M. Kietrys et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

RNA Targeting by Functionally Orthogonal Type VI-A CRISPR-Cas Enzymes

(2017) Alexandra East-Seletsky et al.   MOLECULAR CELL

Nucleic acid detection with CRISPR-Cas13a/C2c2

(2017) Jonathan S. Gootenberg et al.   SCIENCE

Two distinct RNase activities of CRISPR-C2c2 enable guide-RNA processing and RNA detection

(2016) Alexandra East-Seletsky et al.   NATURE

Cas9 cleavage assay for pre-screening of sgRNAs using nicking triggered isothermal amplification

(2016) Kaixiang Zhang et al.   Chemical Science

Dumbbell-PCR: a method to quantify specific small RNA variants with a single nucleotide resolution at terminal sequences

(2015) Shozo Honda et al.   NUCLEIC ACIDS RESEARCH

A Bubble-Mediated Intelligent Microscale Electrochemical Device for Single-Step Quantitative Bioassays

(2014) Fan Yang et al.   ADVANCED MATERIALS

Ultrasensitive Electrochemical Detection of MicroRNA Based on an Arched Probe Mediated Isothermal Exponential Amplification

(2014) Yanyan Yu et al.   ANALYTICAL CHEMISTRY

Zwitterionic Phenyl Layers: Finally, Stable, Anti-Biofouling Coatings that Do Not Passivate Electrodes

(2013) Alicia L. Gui et al.   ACS Applied Materials & Interfaces

MicroRNAs and their targets: recognition, regulation and an emerging reciprocal relationship

(2012) Amy E. Pasquinelli   NATURE REVIEWS GENETICS

A Programmable Dual-RNA-Guided DNA Endonuclease in Adaptive Bacterial Immunity

(2012) M. Jinek et al.   SCIENCE

Electrochemical Sensors and Biosensors

(2011) Danielle W. Kimmel et al.   ANALYTICAL CHEMISTRY

Northern blotting analysis of microRNAs, their precursors and RNA interference triggers

(2011) Edyta Koscianska et al.   BMC MOLECULAR BIOLOGY

Expanding the Rule Set of DNA Circuitry with Associative Toehold Activation

(2011) Xi Chen   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

CRISPR/Cas, the Immune System of Bacteria and Archaea

(2010) P. Horvath et al.   SCIENCE

Causes and consequences of microRNA dysregulation in cancer

(2009) Carlo M. Croce   NATURE REVIEWS GENETICS

Programming biomolecular self-assembly pathways

(2008) Peng Yin et al.   NATURE

MicroRNAs accurately identify cancer tissue origin

(2008) Nitzan Rosenfeld et al.   NATURE BIOTECHNOLOGY

High-throughput stem-loop RT-qPCR miRNA expression profiling using minute amounts of input RNA

(2008) Pieter Mestdagh et al.   NUCLEIC ACIDS RESEARCH