A heterozygous germline CD100 mutation in a family with primary sclerosing cholangitis

Gain-of-Function Mutations: An Emerging Advantage for Cancer Biology

(2019) Yongsheng Li et al.   TRENDS IN BIOCHEMICAL SCIENCES

Interferon-γ-dependent immune responses contribute to the pathogenesis of sclerosing cholangitis in mice

(2019) Gevitha Ravichandran et al.   JOURNAL OF HEPATOLOGY

Carboxyl-Terminal Src Kinase Binds CD28 upon Activation and Mutes Downstream Signaling

(2019) Sigrid S. Skånland et al.   JOURNAL OF IMMUNOLOGY

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(2019) E. M. Kuklina   BIOCHEMISTRY-MOSCOW

Epidemiology, determinants, and management of AIDS cholangiopathy: A review

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Animal models of cholestasis: An update on inflammatory cholangiopathies

(2018) Valeria Mariotti et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

Mutations in Disordered Regions Can Cause Disease by Creating Dileucine Motifs

(2018) Katrina Meyer et al.   CELL

Gut and liver T-cells of common clonal origin in primary sclerosing cholangitis-inflammatory bowel disease

(2017) Eva Kristine Klemsdal Henriksen et al.   JOURNAL OF HEPATOLOGY

Genetics of primary sclerosing cholangitis and pathophysiological implications

(2017) Xiaojun Jiang et al.   Nature Reviews Gastroenterology & Hepatology

Intact CD100–CD72 Interaction Necessary for TCR-Induced T Cell Proliferation

(2017) Xiaojun Jiang et al.   Frontiers in Immunology

Soluble SEMA4D/CD100: A novel immunoregulator in infectious and inflammatory diseases

(2016) Kimia T. Maleki et al.   CLINICAL IMMUNOLOGY

The gut microbial profile in patients with primary sclerosing cholangitis is distinct from patients with ulcerative colitis without biliary disease and healthy controls

(2016) Martin Kummen et al.   GUT

Human Head and Neck Squamous Cell Carcinoma–Associated Semaphorin 4D Induces Expansion of Myeloid-Derived Suppressor Cells

(2016) Rania H. Younis et al.   JOURNAL OF IMMUNOLOGY

Normalizing the environment recapitulates adult human immune traits in laboratory mice

(2016) Lalit K. Beura et al.   NATURE

Genome-wide association study of primary sclerosing cholangitis identifies new risk loci and quantifies the genetic relationship with inflammatory bowel disease

(2016) Sun-Gou Ji et al.   NATURE GENETICS

Analysis of five chronic inflammatory diseases identifies 27 new associations and highlights disease-specific patterns at shared loci

(2016) David Ellinghaus et al.   NATURE GENETICS

Analyzing and interpreting genome data at the network level with ConsensusPathDB

(2016) Ralf Herwig et al.   Nature Protocols

Primary Sclerosing Cholangitis

(2016) Konstantinos N. Lazaridis et al.   NEW ENGLAND JOURNAL OF MEDICINE

A review of the medical treatment of primary sclerosing cholangitis in the 21st century

(2015) Elizabeth C. Goode et al.   Therapeutic Advances in Chronic Disease

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(2014) S. Anders et al.   BIOINFORMATICS

Loss of CD28 Expression by Liver-Infiltrating T Cells Contributes to Pathogenesis of Primary Sclerosing Cholangitis

(2014) Evaggelia Liaskou et al.   GASTROENTEROLOGY

Guidelines for genetic studies in single patients: lessons from primary immunodeficiencies

(2014) Jean-Laurent Casanova et al.   JOURNAL OF EXPERIMENTAL MEDICINE

The p90 RSK Family Members: Common Functions and Isoform Specificity

(2013) R. Lara et al.   CANCER RESEARCH

IFN-γ inhibits liver progenitor cell proliferation in HBV-infected patients and in 3,5-diethoxycarbonyl-1,4-dihydrocollidine diet-fed mice

(2013) Hong-lei Weng et al.   JOURNAL OF HEPATOLOGY

Primary sclerosing cholangitis

(2013) Gideon M Hirschfield et al.   LANCET

Protection against colitis by CD100-dependent modulation of intraepithelial γδ T lymphocyte function

(2013) T F Meehan et al.   Mucosal Immunology

Dense genotyping of immune-related disease regions identifies nine new risk loci for primary sclerosing cholangitis

(2013) Jimmy Z Liu et al.   NATURE GENETICS

JAKs and STATs in Immunity, Immunodeficiency, and Cancer

(2013) John J. O'Shea et al.   NEW ENGLAND JOURNAL OF MEDICINE

Evolving Bacterial Envelopes and Plasticity of TLR2-Dependent Responses: Basic Research and Translational Opportunities

(2013) Junbin Li et al.   Frontiers in Immunology

Genome-wide association analysis in Primary sclerosing cholangitis and ulcerative colitis identifies risk loci atGPR35andTCF4

(2012) David Ellinghaus et al.   HEPATOLOGY

The CD100 Receptor Interacts with Its Plexin B2 Ligand to Regulate Epidermal γδ T Cell Function

(2012) Deborah A. Witherden et al.   IMMUNITY

Extended analysis of a genome-wide association study in primary sclerosing cholangitis detects multiple novel risk loci

(2012) Trine Folseraas et al.   JOURNAL OF HEPATOLOGY

Fiji: an open-source platform for biological-image analysis

(2012) Johannes Schindelin et al.   NATURE METHODS

Fine mapping and replication of genetic risk loci in primary sclerosing cholangitis

(2012) Brijesh Srivastava et al.   SCANDINAVIAN JOURNAL OF GASTROENTEROLOGY

The Genome Analysis Toolkit: A MapReduce framework for analyzing next-generation DNA sequencing data

(2010) A. McKenna et al.   GENOME RESEARCH

A map of human genome variation from population-scale sequencing

(2010) Richard M. Durbin et al.   NATURE

Genome-wide association analysis in primary sclerosing cholangitis identifies two non-HLA susceptibility loci

(2010) Espen Melum et al.   NATURE GENETICS

A method and server for predicting damaging missense mutations

(2010) Ivan A Adzhubei et al.   NATURE METHODS

Differential expression analysis for sequence count data

(2010) Simon Anders et al.   GENOME BIOLOGY

TopHat: discovering splice junctions with RNA-Seq

(2009) Cole Trapnell et al.   BIOINFORMATICS

Fast and accurate short read alignment with Burrows-Wheeler transform

(2009) H. Li et al.   BIOINFORMATICS

Diagnosis and management of primary sclerosing cholangitis

(2009) Roger Chapman et al.   HEPATOLOGY