A comprehensive review on chlorpyrifos toxicity with special reference to endocrine disruption: Evidence of mechanisms, exposures and mitigation strategies

Medium and long-term effects of low doses of Chlorpyrifos during the postnatal, preweaning developmental stage on sociability, dominance, gut microbiota and plasma metabolites

(2020) Cristian Perez-Fernandez et al.   ENVIRONMENTAL RESEARCH

Acute toxic effects of chlorpyrifos on pseudobranchial neurosecretory system, brain regions and locomotory behavior of an air-breathing catfish, Heteropneustes fossilis (Bloch 1794)

(2020) Ajeet Kr. Mishra et al.   DRUG AND CHEMICAL TOXICOLOGY

Effects of chlorpyrifos on the crustacean Litopenaeus vannamei

(2020) Edisson Duarte-Restrepo et al.   PLoS One

Organophosphate Pesticide Exposure and Breast Cancer Risk: A Rapid Review of Human, Animal, and Cell-Based Studies

(2020) Kailynn June Yang et al.   International Journal of Environmental Research and Public Health

Molecular interactions of chlorpyrifos and its environmental degradation products with human sex hormone-binding globulin: an in silico study

(2019) Jnyandeep Hazarika et al.   JOURNAL OF APPLIED TOXICOLOGY

Effects of prenatal and postnatal exposure to organophosphate pesticides on child neurodevelopment in different age groups: a systematic review

(2019) Ratana Sapbamrer et al.   ENVIRONMENTAL SCIENCE AND POLLUTION RESEARCH

Effects of Chlorpyrifos on Cholinesterase and Serine Lipase Activities and Lipid Metabolism in Brains of Rainbow Trout (Oncorhynchus mykiss)

(2019) J B Greer et al.   TOXICOLOGICAL SCIENCES

Chlorpyrifos-induced reproductive toxicity in rats could be partly relieved under high-fat diet

(2019) Jinwang Li et al.   CHEMOSPHERE

Toxicity assessment of chlorpyrifos on different organs of rat: exploitation of microbial-based enzymatic system for neutralization

(2019) Shelly Sharma et al.   ENVIRONMENTAL SCIENCE AND POLLUTION RESEARCH

Rapid degradation of the organophosphate pesticide – Chlorpyrifos by a novel strain of Pseudomonas nitroreducens AR-3

(2019) Aswathi Aswathi et al.   BIORESOURCE TECHNOLOGY

APOE genotype and postnatal chlorpyrifos exposure modulate gut microbiota and cerebral short-chain fatty acids in preweaning mice

(2019) Laia Guardia-Escote et al.   FOOD AND CHEMICAL TOXICOLOGY

Comparative examination on synergistic toxicities of chlorpyrifos, acephate, or tetraconazole mixed with pyrethroid insecticides to honey bees (Apis mellifera L.)

(2019) Yanhua Wang et al.   ENVIRONMENTAL SCIENCE AND POLLUTION RESEARCH

Microbiota and organophosphates

(2019) Pablo Roman et al.   NEUROTOXICOLOGY

Pesticides With Potential Thyroid Hormone-Disrupting Effects: A Review of Recent Data

(2019) Michelle Leemans et al.   Frontiers in Endocrinology

Evaluation of chlorpyrifos toxicity through a 28-day study: Cholinesterase activity, oxidative stress responses, parent compound/metabolite levels, and primary DNA damage in blood and brain tissue of adult male Wistar rats

(2018) Nevenka Kopjar et al.   CHEMICO-BIOLOGICAL INTERACTIONS

Magnesium sulfate and calcium channel blocking drugs as antidotes for acute organophosphorus insecticide poisoning – a systematic review and meta-analysis

(2018) Miran Brvar et al.   CLINICAL TOXICOLOGY

Tadpoles of the horned frog Ceratophrys ornata exhibit high sensitivity to chlorpyrifos for conventional ecotoxicological and novel bioacoustic variables

(2018) C. Salgado Costa et al.   ENVIRONMENTAL POLLUTION

Inhibition of cholinergic and non-cholinergic targets following subacute exposure to chlorpyrifos in normal and high fat fed male C57BL/6J mice

(2018) George E. Howell et al.   FOOD AND CHEMICAL TOXICOLOGY

Polluting Developing Brains — EPA Failure on Chlorpyrifos

(2018) Virginia A. Rauh   NEW ENGLAND JOURNAL OF MEDICINE

The Organophosphorus Pesticide Chlorpyrifos Induces Sex-Specific Airway Hyperreactivity in Adult Rats

(2018) Frances C Shaffo et al.   TOXICOLOGICAL SCIENCES

Thyroid-disrupting chemicals and brain development: an update

(2018) Bilal B Mughal et al.   Endocrine Connections

Paraoxonase-1 genetic polymorphisms in organophosphate metabolism

(2018) Efthimios Dardiotis et al.   TOXICOLOGY

Effects of the pesticide chlorpyrifos on breast cancer disease. Implication of epigenetic mechanisms

(2018) C. Ventura et al.   JOURNAL OF STEROID BIOCHEMISTRY AND MOLECULAR BIOLOGY

Chlorpyrifos disturbs hepatic metabolism associated with oxidative stress and gut microbiota dysbiosis in adult zebrafish

(2018) Xiaoyu Wang et al.   COMPARATIVE BIOCHEMISTRY AND PHYSIOLOGY C-TOXICOLOGY & PHARMACOLOGY

Developmental neurotoxicity of succeeding generations of insecticides

(2017) Yael Abreu-Villaça et al.   ENVIRONMENT INTERNATIONAL

Developmental neurotoxicity of the organophosphorus insecticide chlorpyrifos: from clinical findings to preclinical models and potential mechanisms

(2017) Richard D. Burke et al.   JOURNAL OF NEUROCHEMISTRY

Chlorpyrifos and chlorpyrifos oxon impair the transport of membrane bound organelles in rat cortical axons

(2017) Jie Gao et al.   NEUROTOXICOLOGY

Effects of Endocrine-Disrupting Chemicals and Epigenetic Modifications in Ovarian Cancer: A Review

(2017) Ratika Samtani et al.   Reproductive Sciences

Effects of acute exposure to chlorpyrifos on cholinergic and non-cholinergic targets in normal and high-fat fed male C57BL/6J mice

(2017) Sandeep Kondakala et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY

Chlorpyrifos poisoning and its implications in human fatal cases: A forensic perspective with reference to Indian scenario

(2017) Ankush L. Rathod et al.   Journal of Forensic and Legal Medicine

Extrapyramidal effects of acute organophosphate poisoning

(2016) Kent K. Reji et al.   CLINICAL TOXICOLOGY

Individual and combined effect of chlorpyrifos and cypermethrin on reproductive system of adult male albino rats

(2016) Eman Ahmad Alaa-Eldin et al.   ENVIRONMENTAL SCIENCE AND POLLUTION RESEARCH

An international database for pesticide risk assessments and management

(2016) Kathleen A. Lewis et al.   HUMAN AND ECOLOGICAL RISK ASSESSMENT

Pesticide chlorpyrifos acts as an endocrine disruptor in adult rats causing changes in mammary gland and hormonal balance

(2016) Clara Ventura et al.   JOURNAL OF STEROID BIOCHEMISTRY AND MOLECULAR BIOLOGY

ROS-dependent genotoxicity, cell cycle perturbations and apoptosis in mouse bone marrow cells exposed to formulated mixture of cypermethrin and chlorpyrifos

(2016) Lalit K. S. Chauhan et al.   MUTAGENESIS

Pharmacological treatment of organophosphorus insecticide poisoning: the old and the (possible) new

(2015) Michael Eddleston et al.   BRITISH JOURNAL OF CLINICAL PHARMACOLOGY

The organophosphate insecticide chlorpyrifos confers its genotoxic effects by inducing DNA damage and cell apoptosis

(2015) Diqiu Li et al.   CHEMOSPHERE

Neonatal chlorpyrifos exposure induces loss of dopaminergic neurons in young adult rats

(2015) Jie Zhang et al.   TOXICOLOGY

The effect of HMGB1 on sub-toxic chlorpyrifos exposure-induced neuroinflammation in amygdala of neonatal rats

(2015) Jing Tian et al.   TOXICOLOGY

Evaluation of genotoxic potential of commonly used organophosphate pesticides in peripheral blood lymphocytes of rats

(2014) A Ojha et al.   HUMAN & EXPERIMENTAL TOXICOLOGY

Protective role of Nigella sativa oil against reproductive toxicity, hormonal alterations, and oxidative damage induced by chlorpyrifos in male rats

(2014) Rachid Mosbah et al.   TOXICOLOGY AND INDUSTRIAL HEALTH

Acetylcholinesterase Inhibitors: Pharmacology and Toxicology

(2013) Mirjana B. Colovic et al.   Current Neuropharmacology

Chlorpyrifos induced toxicity in reproductive organs of female Wistar rats

(2013) Kumari Nishi et al.   FOOD AND CHEMICAL TOXICOLOGY

Genotoxicity evaluation of chlorpyrifos: a gender related approach in regular toxicity testing

(2013) Mansur A. Sandhu et al.   JOURNAL OF TOXICOLOGICAL SCIENCES

Is there a role for progesterone in the management of acute organophosphate poisoning during pregnancy?

(2013) Mostafa Jafarzadeh et al.   MEDICAL HYPOTHESES

Chlorpyrifos: Weight of evidence evaluation of potential interaction with the estrogen, androgen, or thyroid pathways

(2013) Daland R. Juberg et al.   REGULATORY TOXICOLOGY AND PHARMACOLOGY

Chlorpyrifos acute exposure induces hyperglycemia and hyperlipidemia in rats

(2012) Carmine Inês Acker et al.   CHEMOSPHERE

Impact of chronic exposure to low doses of chlorpyrifos on the intestinal microbiota in the Simulator of the Human Intestinal Microbial Ecosystem (SHIME®) and in the rat

(2012) Claire Joly et al.   ENVIRONMENTAL SCIENCE AND POLLUTION RESEARCH

Microbial degradation of chlorpyrifos in liquid media and soil

(2012) Zia Chishti et al.   JOURNAL OF ENVIRONMENTAL MANAGEMENT

Sex dimorphic behaviors as markers of neuroendocrine disruption by environmental chemicals: The case of chlorpyrifos

(2012) A. Venerosi et al.   NEUROTOXICOLOGY

Does the home environment and the sex of the child modify the adverse effects of prenatal exposure to chlorpyrifos on child working memory?

(2012) Megan K. Horton et al.   NEUROTOXICOLOGY AND TERATOLOGY

Functional consequences of repeated organophosphate exposure: Potential non-cholinergic mechanisms

(2012) A.V. Terry   PHARMACOLOGY & THERAPEUTICS

Association between urinary 3, 5, 6-trichloro-2-pyridinol, a metabolite of chlorpyrifos and chlorpyrifos-methyl, and serum T4 and TSH in NHANES 1999–2002

(2012) Gamola Z. Fortenberry et al.   SCIENCE OF THE TOTAL ENVIRONMENT

Differential mechanisms of action are involved in chlorpyrifos effects in estrogen-dependent or -independent breast cancer cells exposed to low or high concentrations of the pesticide

(2012) Clara Ventura et al.   TOXICOLOGY LETTERS

Toxicity of Chlorpyrifos to Larval Rana dalmatina: Acute and Chronic Effects on Survival, Development, Growth and Gill Apparatus

(2011) Ilaria Bernabò et al.   ARCHIVES OF ENVIRONMENTAL CONTAMINATION AND TOXICOLOGY

Developmental neurotoxicity targeting hepatic and cardiac sympathetic innervation: Effects of organophosphates are distinct from those of glucocorticoids

(2011) Frederic J. Seidler et al.   BRAIN RESEARCH BULLETIN

Chronic chlorpyrifos-induced oxidative changes in the testes and pituitary gland of Wistar rats: Ameliorative effects of vitamin C

(2011) M. Shittu et al.   PESTICIDE BIOCHEMISTRY AND PHYSIOLOGY

The Organophosphate Chlorpyrifos Interferes with the Responses to 17β-Estradiol in the Digestive Gland of the Marine Mussel Mytilus galloprovincialis

(2011) Laura Canesi et al.   PLoS One

Hodgkin Lymphoma and Pesticides Exposure in Men: A Canadian Case-Control Study

(2011) Chandima P. Karunanayake et al.   Journal of Agromedicine

Genotoxic effects of chlorpyrifos, cypermethrin, endosulfan and 2,4-D on human peripheral lymphocytes cultured from smokers and nonsmokers

(2010) Suleyman Sandal et al.   ENVIRONMENTAL TOXICOLOGY

Anti-androgenic endocrine disrupting activities of chlorpyrifos and piperophos

(2010) Gunda Viswanath et al.   JOURNAL OF STEROID BIOCHEMISTRY AND MOLECULAR BIOLOGY

Genotoxicity of chlorpyrifos and cypermethrin to ICR mouse hepatocytes

(2010) Yong Cui et al.   TOXICOLOGY MECHANISMS AND METHODS

Essential role of monocytes and macrophages in the progression of acute pancreatitis

(2010) Pratima Shrivastava   WORLD JOURNAL OF GASTROENTEROLOGY

Comparative toxicity of chlorpyrifos and its oxon derivatives to soil microbial activity by combined methods

(2009) Fei Wang et al.   CHEMOSPHERE

Toxicity of selected pesticides to freshwater shrimp, Paratya australiensis (Decapoda: Atyidae): Use of time series acute toxicity data to predict chronic lethality

(2009) A. Kumar et al.   ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY

Endocrine-Disrupting Chemicals: An Endocrine Society Scientific Statement

(2009) Evanthia Diamanti-Kandarakis et al.   ENDOCRINE REVIEWS

Chlorpyrifos and endosulfan affect buffalo oocyte maturation, fertilization, and embryo development in vitro directly and through cumulus cells

(2009) S. Nandi et al.   ENVIRONMENTAL TOXICOLOGY

TOXICITY OF TWO INSECTICIDES TO CALIFORNIA, USA, ANURANS AND ITS RELEVANCE TO DECLINING AMPHIBIAN POPULATIONS

(2009) Donald W. Sparling et al.   ENVIRONMENTAL TOXICOLOGY AND CHEMISTRY

Toxic responses to deltamethrin (DM) low doses on gonads, sex hormones and lipoperoxidation in male rats following subcutaneous treatments

(2009) Chargui Issam et al.   JOURNAL OF TOXICOLOGICAL SCIENCES

Genotoxicity evaluation of chlorpyrifos to amphibian Chinese toad (Amphibian: Anura) by Comet assay and Micronucleus test

(2009) XiaoHui Yin et al.   MUTATION RESEARCH-GENETIC TOXICOLOGY AND ENVIRONMENTAL MUTAGENESIS

Oxidative stress, steroid hormone concentrations and acetylcholinesterase activity in Oreochromis niloticus exposed to chlorpyrifos

(2009) Elif Özcan Oruç   PESTICIDE BIOCHEMISTRY AND PHYSIOLOGY

Long-term sex selective hormonal and behavior alterations in mice exposed to low doses of chlorpyrifos in utero

(2009) Julia A. Haviland et al.   REPRODUCTIVE TOXICOLOGY

Chlorpyrifos induced reproductive toxicity in male mice

(2009) Amina T. Farag et al.   REPRODUCTIVE TOXICOLOGY

Developmental Exposure to Chlorpyrifos Induces Alterations in Thyroid and Thyroid Hormone Levels Without Other Toxicity Signs in Cd1 Mice

(2009) Simona De Angelis et al.   TOXICOLOGICAL SCIENCES

Comparative chlorpyrifos pharmacokinetics via multiple routes of exposure and vehicles of administration in the adult rat

(2009) Jordan Ned Smith et al.   TOXICOLOGY

Chlorpyrifos induces oxidative stress in oligodendrocyte progenitor cells

(2009) Marilyn D. Saulsbury et al.   TOXICOLOGY

Genotoxicity assessment of acute exposure of chlorpyrifos to freshwater fish Channa punctatus (Bloch) using micronucleus assay and alkaline single-cell gel electrophoresis

(2008) Daoud Ali et al.   CHEMOSPHERE

Laboratory toxicity test and post-exposure feeding inhibition using the giant freshwater prawn Macrobrachium rosenbergii

(2008) Kriengkrai Satapornvanit et al.   CHEMOSPHERE

Review of the Toxicology of Chlorpyrifos With an Emphasis on Human Exposure and Neurodevelopment

(2008) David L. Eaton et al.   CRITICAL REVIEWS IN TOXICOLOGY

Food processing a tool to pesticide residue dissipation – A review

(2008) Geetanjali Kaushik et al.   FOOD RESEARCH INTERNATIONAL

The Role of Neurotrophins During Early Development

(2008) PAULETTE BERND   GENE EXPRESSION

The comet assay as an indicator test for germ cell genotoxicity

(2008) G SPEIT et al.   MUTATION RESEARCH-REVIEWS IN MUTATION RESEARCH

Lipid peroxidation and oxidative stress in rat erythrocytes induced by chlorpyrifos and the protective effect of zinc

(2008) Sameeh A. Mansour et al.   PESTICIDE BIOCHEMISTRY AND PHYSIOLOGY

Circulating estradiol in men is inversely related to urinary metabolites of nonpersistent insecticides

(2008) John D. Meeker et al.   REPRODUCTIVE TOXICOLOGY

Examining the joint toxicity of chlorpyrifos and atrazine in the aquatic species: Lepomis macrochirus, Pimephales promelas and Chironomus tentans

(2007) W. Tyler Mehler et al.   ENVIRONMENTAL POLLUTION

Characterization of chlorpyrifos-induced apoptosis in placental cells

(2007) Marilyn D. Saulsbury et al.   TOXICOLOGY