4.7 Review

Deciphering and engineering photosynthetic cyanobacteria for heavy metal bioremediation

Journal

SCIENCE OF THE TOTAL ENVIRONMENT
Volume 761, Issue -, Pages -

Publisher

ELSEVIER
DOI: 10.1016/j.scitotenv.2020.144111

Keywords

Cyanobacteria; Heavy metals; Bioremediation; Resistance mechanisms; Engineering strategies

Funding

  1. National Key Research and Development Program of China [2018YFA0903600, 2020YFA0906800, 2019YFA0904600, 2018YFA0903000]
  2. National Natural Science Foundation of China [31901017, 31770035, 91751102, 31770100, 31972931, 21621004]
  3. Tianjin Synthetic Biotechnology Innovation Capacity Improvement Project [TSBICIP-KJGG-007]

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This review highlights the potential of photosynthetic cyanobacteria as a promising solution for heavy metal bioremediation, discussing their resistance mechanisms, applications using live or dead cells, and strategies for enhancing remediation. The challenges and perspectives for improving bioremediation of heavy metals by cyanobacteria are also presented.
Environmental pollution caused by heavy metals has received worldwide attentions due to their ubiquity, poor degradability and easy bioaccumulation in host cells. As one potential solution, photosynthetic cyanobacteria have been considered as promising remediation chassis and widely applied in various bioremediation processes of heavy-metals. Meanwhile, deciphering resistant mechanisms and constructing tolerant chassis towards heavy metals could greatly contribute to the successful application of the cyanobacteria-based bioremediation in the future. In this review, first we summarized recent application of cyanobacteria in heavy metals bioremediation using either live or dead cells. Second, resistant mechanisms and strategies for enhancing cyanobacterial bioremediation of heavy metals were discussed. Finally, potential challenges and perspectives for improving bioremediation of heavy metals by cyanobacteria were presented. (C) 2020 Elsevier B.V. All rights reserved.

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