Article
Environmental Sciences
A. Saravanan, Ponnusamy Senthil Kumar, Pham Anh Duc, Gayathri Rangasamy
Summary: Heavy metals pose hazardous risks to humans and animals, even at low concentrations. Microbial bioremediation offers a promising approach to removing these pollutants from contaminated water. This review focuses on the sources, occurrence, and human exposure risk of toxic heavy metals, as well as the role of microbial bioremediation in mitigating water pollution. Factors affecting microbial bioremediation, the interaction between microorganisms and pollutants, and emerging strategies and technologies, such as genetically engineered microorganisms and microorganism-aided nanotechnology, are also discussed as critical tools for water pollutant elimination.
Article
Engineering, Environmental
Hillol Chakdar, Shobit Thapa, Amit Srivastava, Pratyoosh Shukla
Summary: Cyanobacteria have emerged as a potential option for bioremediation of heavy metals due to their unique adaptations and robust metabolic machineries. Understanding their physiological responses and regulation at the molecular level is necessary to identify candidate genes and proteins for improving bioremediation efficiency. These approaches might pave new possibilities of implementing genetic engineering strategies in the future.
JOURNAL OF HAZARDOUS MATERIALS
(2022)
Article
Green & Sustainable Science & Technology
Carla Cilliers, Olga Neveling, Shepherd M. Tichapondwa, Evans M. N. Chirwa, Hendrik G. Brink
Summary: This research aimed to improve the scalability and cleaner production of a lead bioremediation process by gaining a better understanding of its dominant mechanisms. The study found that the presence of different lead concentrations and complementary anions had significant effects on the composition and structure of the resulting precipitate.
JOURNAL OF CLEANER PRODUCTION
(2022)
Review
Microbiology
Badriyah Shadid Alotaibi, Maryam Khan, Saba Shamim
Summary: The increase in anthropogenic activities has led to the release of pollutants into the environment, with heavy metals being a major contributor to the escalating problem of environmental pollution. Traditional physical and chemical methods of heavy metal removal have limitations, prompting the exploration of microbial bioremediation, particularly using bacteria like Bacillus spp. which have proven effective in removing heavy metals through biosorption and molecular mechanisms.
Review
Polymer Science
Katarina Balikova, Hana Vojtkova, Eva Duborska, Hyunjung Kim, Peter Matus, Martin Urik
Summary: Research on Pseudomonas biofilms, particularly the study of exopolysaccharides (ExPs), has shown their potential in solving environmental issues such as heavy metal contamination. These findings have practical applications in medical, agricultural, and environmental sciences, offering viable solutions to the imminent risk heavy metal contamination poses to the environment and human health. The research aims to provide comprehensive information on the biosynthesis of ExPs and their usage in remediation techniques, including wastewater treatment and soil remediation.
Review
Environmental Sciences
Muhammad Usama Saeed, Nazim Hussain, Aleena Sumrin, Areej Shahbaz, Saman Noor, Muhammad Bilal, Lotfi Aleya, Hafiz M. N. Iqbal
Summary: The demand for innovative waste treatment techniques has increased due to strict waste discharge guidelines. Wastewater treatment is a significant process, requiring high activities and densities of microorganisms. Improperly treated waste from the pharmaceutical industry has harmful impacts on the environment and public health. Bioremediation utilizing microorganisms is a promising technology to remove heavy metals from polluted water and soil. Microorganisms play a crucial role in heavy metal bioremediation. The use of microorganisms in nanoparticle synthesis can reduce industry expenses and contribute to sustainable production.
SCIENCE OF THE TOTAL ENVIRONMENT
(2022)
Article
Biology
Md. Shakir Ahammed, Md. Abdul Baten, Muhammad Aslam Ali, Shahin Mahmud, Md. Sirajul Islam, Bhim Sen Thapa, Md. Aminul Islam, Md. Alim Miah, Tanmoy Roy Tusher
Summary: This study investigated the ability of microalgae and cyanobacteria to remove pollutants, especially heavy metals, from polluted river water. The results showed that both microalgae and cyanobacteria significantly reduced the pollutants and heavy metal concentrations. However, their efficiency in pollutant removal varied depending on the species.
Review
Microbiology
Samiksha Joshi, Saurabh Gangola, Geeta Bhandari, Narendra Singh Bhandari, Deepa Nainwal, Anju Rani, Sumira Malik, Petr Slama
Summary: The increasing rate of industrialization, anthropogenic, and geological activities have led to higher concentration of heavy metals in the environment, posing potential threats to humans, animals, and aquatic organisms. Bioremediation using rhizospheric microorganisms is a reliable solution for reducing the toxicity of these contaminants in an environmentally safe manner. By exploiting microbial metabolism and plant growth promoting bacteria, the concentration of heavy metals can be minimized for effective environmental clean-up.
FRONTIERS IN MICROBIOLOGY
(2023)
Article
Engineering, Environmental
Priyanka, Shiv Kumar Dwivedi
Summary: Wastewater pollution is a major global environmental issue, and conventional methods for HM removal are considered inadequate for HMs concentrations below 100 mg/L. Detoxification of heavy metals using fungi has emerged as a viable solution due to their higher biosorption and bioaccumulation potential. Environmental and operational factors such as pH, temperature, metal ion concentration, time, and flow rate have significant effects on fungi growth and metabolic functions.
JOURNAL OF WATER PROCESS ENGINEERING
(2023)
Review
Environmental Sciences
Manikka Kubendran Aravind, Nagamalai Sakthi Vignesh, Santhalingam Gayathri, Nair Anjitha, Kottilinkal Manniath Athira, Sathaiah Gunaseelan, Malaisamy Arunkumar, Ashokkumar Sanjaykumar, Sankar Karthikumar, Innasi Muthu Ganesh Moorthy, Balasubramaniem Ashokkumar, Arivalagan Pugazhendhi, Perumal Varalakshmi
Summary: Phycoremediation of heavy metals has gained significant attention as an emerging practice for metal removal in diverse environmental matrices. However, the complex and haphazard physicochemical state of metal polluted sites due to irregular waste discharge poses challenges for the application of microalgae in metal bioremediation. This review focuses on evaluating existing microalgal strategies for metal removal through various processes and provides insights for choosing efficient metal remediation tactics based on the polluted environment. Additionally, the adsorption mechanism of microalgae for metal removal is investigated using principal component analysis with different metals and factors. The review comprehensively discusses suitable strategies for different heavy metal removal and addresses complications and solutions in microalgal metal removal mechanisms.
Review
Environmental Sciences
Zhanfei He, Jiaquan Shen, Qunqun Li, Yingli Yang, Daoyong Zhang, Xiangliang Pan
Summary: Bacteria have developed a wide range of metal(loid) resistance genes (MRGs) to protect their key components from toxic metal(loid)s. These MRGs have been applied in environmental fields, such as developing biosensors for monitoring environmental metal(loid)s and utilizing MRGs-carrying microorganisms for environmental remediation.
SCIENCE OF THE TOTAL ENVIRONMENT
(2023)
Review
Biochemistry & Molecular Biology
Saeed Ranjbar, Francisco Xavier Malcata
Summary: Contamination of the biosphere by heavy metals has become a global concern. Microalgae have emerged as promising organisms for the biological removal of heavy metal pollutants. However, their poor productivity under abiotic stress conditions hinders their large-scale application. Recent advances in genetic engineering and metabolic engineering have provided opportunities to enhance the metal stress tolerance and phycoremediation capabilities of microalgae. This review summarizes the current understanding of metal stress mitigation mechanisms in microalgae and discusses the potential of transgenic microalgae for heavy metal phycoremediation.
Review
Engineering, Environmental
Cheng-Cheng Dang, Guo-Jun Xie, Bing-Feng Liu, De-Feng Xing, Jie Ding, Nan-Qi Ren
Summary: This review examines the coupling of heavy metals reduction with methane oxidation and identifies gaps and opportunities for future research. It discusses potential applications for global methane mitigation, elements cycle, and heavy metals detoxification, as well as future research opportunities for efficient practical application.
JOURNAL OF HAZARDOUS MATERIALS
(2021)
Article
Infectious Diseases
Han-Sheng Zhu, Xiao Liang, Jun-Cheng Liu, Han-Yang Zhong, Yuan-Hang Yang, Wen-Peng Guan, Zong-Jun Du, Meng-Qi Ye
Summary: This study investigated the microbial community of marine sediments under Cu (II) and lincomycin stress, and identified a strain, ZC255, that exhibited high resistance to antibiotics and heavy metals. The strain showed superior removal efficiency of Cu (II) and lincomycin, making it a promising candidate for pollution bioremediation applications.
Review
Environmental Sciences
Shafiul Haque, Neha Srivastava, Dan Bahadur Pal, Mustfa F. Alkhanani, Atiah H. Almalki, Mohammed Y. Areeshi, Ravi Naidu, Vijai Kumar Gupta
Summary: This review discusses the role of microbiomes in effectively remediating/degrading petroleum hydrocarbons and heavy metals in contaminated soil. It also delves into the possible degradation mechanisms of these pollutants and their existing limitations.
SCIENCE OF THE TOTAL ENVIRONMENT
(2022)
Article
Biochemistry & Molecular Biology
Yaru Xie, Lei Chen, Tao Sun, Jingjing Jiang, Lijin Tian, Jinyu Cui, Weiwen Zhang
Summary: The gene slr1.512 related to bicarbonate transport was found to be involved in high light acclimation in cyanobacteria, enhancing tolerance towards excess light stress. The knockout mutant of slr1.512 showed increased growth and altered accumulation of toxic reactive oxygen species under high light, demonstrating its potential as a target for engineering cyanobacteria for higher light tolerance.
BIOCHIMICA ET BIOPHYSICA ACTA-BIOENERGETICS
(2021)
Article
Chemistry, Multidisciplinary
Meihui Cui, Gaoju Pang, Tao Zhang, Tao Sun, Lili Zhang, Ruru Kang, Xin Xue, Huizhuo Pan, Chun Yang, Xinyu Zhang, Jin Chang, Jing Liu, Shufang Zhang, Hanjie Wang
Summary: A study developed an optotheranostic nanosystem for self-diagnosis and long-acting mitigation of ulcerative colitis (UC). The system utilized smartphone optical sensing for disease prescreening and an optogenetic engineered bacteria system for real-time intervention. Treatment with IL-10-secreting EcN effectively suppressed intestinal inflammatory response and protected intestinal mucosa in UC mice.
Article
Biophysics
Xinyu Zhang, Yingying Zhang, Chaonan Zhang, Chun Yang, Ran Tian, Tao Sun, Weiwen Zhang, Jin Chang, Hanjie Wang
Summary: Photodynamic therapy (PDT) shows great potential in cancer treatment, but is limited by the hypoxic tumor environment and poor penetration of short-wavelength light. A novel injectable system containing UCNPs, a photosensitizer, and a strain of cyanobacteria was developed to enhance PDT effects by alleviating tumor hypoxia and eradicating tumors efficiently. The system demonstrated excellent biocompatibility and biosafety, providing a new approach for hypoxia-resistant cancer therapy in the future.
COLLOIDS AND SURFACES B-BIOINTERFACES
(2021)
Article
Biochemical Research Methods
Lianyue Li, Huizhuo Pan, Gaoju Pang, Haoyu Lang, Yue Shen, Tao Sun, Yingying Zhang, Jing Liu, Jin Chang, Jun Kang, Hao Zheng, Hanjie Wang
Summary: In this study, heat-sensitive engineered bacteria were constructed to produce therapeutic proteins in response to thermal stimuli. The precise control of their functions was demonstrated in various model organisms, and it was found that heat stimulation could inhibit tumor growth, providing a new approach for the precise control of engineered bacteria in vivo.
ACS SYNTHETIC BIOLOGY
(2022)
Article
Chemistry, Multidisciplinary
Huizhuo Pan, Tao Sun, Meihui Cui, Ning Ma, Chun Yang, Jing Liu, Gaoju Pang, Baona Liu, Lianyue Li, Xinyu Zhang, Weiwen Zhang, Jin Chang, Hanjie Wang
Summary: The discovery of the gut-brain axis has opened up significant opportunities for exploring new tools to regulate gut microbiota and affect brain functions. In this study, engineered blue-light-responsive probiotics were developed using a micro-nano system, enabling precise manipulation of brain functions.
Article
Nanoscience & Nanotechnology
Lianyue Li, Chun Yang, Binglin Ma, Shenjunjie Lu, Jing Liu, Yiyang Pan, Xuyan Wang, Yiliang Zhang, Hanjie Wang, Tao Sun, Duo Liu
Summary: Genetically modified engineered microorganisms have been encapsulated in hydrogels to treat skin diseases. A photoautotrophic living material containing an engineered microbial consortium has been designed and fabricated, which can function stably for a longer period of time. The living material has been tested in a rat-skin defect model and shown to promote wound healing more effectively compared to control groups.
ACS APPLIED MATERIALS & INTERFACES
(2023)
Article
Engineering, Environmental
Meihui Cui, Wei Ling, Lili Zhang, Yayang Li, Jing Liu, Tao Sun, Binglin Ma, Shenjunjie Lu, Huizhuo Pan, Gaoju Pang, Yingying Zhang, Shufang Zhang, Xian Huang, Peiqi Zhao, Duo Liu, Hanjie Wang
Summary: This article presents a smartphone-controlled bioelectronic drug system for chronic kidney disease monitoring, which allows real-time diagnosis and treatment. The system utilizes a urine-based colorimetric sensor and engineered bacteria to quantify pathology and modulate diseases, with the help of smartphone applications for image capture and wireless transmission.
CHEMICAL ENGINEERING JOURNAL
(2023)
Article
Engineering, Environmental
Tao Sun, Zhixiang Li, Shubin Li, Lei Chen, Weiwen Zhang
Summary: In this study, a fast-growing cyanobacterium was utilized to address inherent issues associated with cyanobacterial strains and achieve CO2-based myo-inositol biosynthesis. Through various strategies, the researchers successfully improved cell growth and achieved the highest production of myo-inositol from CO2 in cyanobacteria. Metabolomic analysis was also applied to further optimize the process.
CHEMICAL ENGINEERING JOURNAL
(2023)
Review
Environmental Sciences
Xiaofei Zhu, Zipeng Li, Yindong Tong, Lei Chen, Tao Sun, Weiwen Zhang
Summary: The over proliferation of harmful cyanobacteria and their cyanotoxins resulted in damaged aquatic ecosystem, polluted drinking water and threatened human health. Cyanophages, as a potential strategy to deal with cyanobacterial blooms, have limited host range and/or lysis efficiency, necessitating the construction of non-natural cyanophages via artificial modification, design and synthesis. This review summarizes the representative cyanophages, explores in-silico design principles, and discusses the progress and challenges of synthesizing artificial cyanophages.
ENVIRONMENTAL RESEARCH
(2023)
Article
Chemistry, Physical
Xinyu Zhang, Ning Ma, Wei Ling, Gaoju Pang, Tao Sun, Jing Liu, Huizhuo Pan, Meihui Cui, Chunli Han, Chun Yang, Jin Chang, Xian Huang, Hanjie Wang
Summary: This study developed a micro-nano optogenetic system based on probiotics for in situ controllable drug delivery in the intestinal tract. Optogenetic engineered Lactococcus lactis was orally administrated and optical signals were remotely controlled using a wearable optical device. The L. lactis could be customized to secrete peptides according to the optical signals. Upconversion microcapsules were introduced to improve the excitation wavelength of the optogenetic system. This strategy has promising biomedical potential for expanding the toolbox for intestinal engineered bacteria.
Article
Engineering, Biomedical
Xinyu Zhang, Gaoju Pang, Tao Sun, Xinyu Liu, Huizhuo Pan, Yingying Zhang, Jing Liu, Jin Chang, Hanjie Wang, Duo Liu
Summary: Microbes are able to regulate brain function through the gut-brain axis. Engineered probiotics and optogenetics provide a promising approach to modulate the gut-brain axis in situ. In this study, a red-light optogenetic gut probiotic was developed for drug delivery and regulation of host behaviors.
Article
Microbiology
Yu Chen, Pingbo Ge, Tao Sun, Jia Feng, Guorui Li, Jiabao Zhang, Jianting Zhou, Jianlan Jiang
Summary: We synthesized and assembled a truncated cyanophage genome called Syn-P4-8 and transferred it into a nonhost strain to investigate interactions between the virus and the host. Coexpression of certain genes enhanced the salt tolerance of the host strain.
MICROBIOLOGY SPECTRUM
(2023)
Review
Microbiology
Zipeng Li, Xiaofei Zhu, Zhengyu Wu, Tao Sun, Yindong Tong
Summary: This review discusses the classification, biosynthetic pathways, and potential applications of cyanotoxins. By examining representative cyanotoxins and their biosynthetic pathways, the review summarizes and compares recent advances in the heterologous biosynthesis of cyanotoxins in vitro and in vivo, and identifies potential applications and solutions to bottlenecks.
Article
Chemistry, Physical
Xinyu Zhang, Ning Ma, Wei Ling, Gaoju Pang, Tao Sun, Jing Liu, Huizhuo Pan, Meihui Cui, Chunli Han, Chun Yang, Jin Chang, Xian Huang, Hanjie Wang
Summary: A micro-nano optogenetic system based on probiotic was developed to achieve in situ controllable drug delivery in the intestinal tract. The system used a wearable optical device to remotely control optical signals, which customized the secretion of peptides by engineered bacteria. The strategy showed potential in regulating metabolism and improving features in rats and mice models, and the introduction of upconversion microcapsules enhanced the penetrability of the optogenetic system.
Article
Environmental Sciences
Toshimi Nakajima, Mao Kuragano, Makoto Yamada, Ryo Sugimoto
Summary: This study compared the contribution of submarine groundwater discharge (SGD) to river nutrient budgets at nearshore and embayment scales, and found that SGD-derived nutrients become more important at larger spatial scales.
SCIENCE OF THE TOTAL ENVIRONMENT
(2024)
Article
Environmental Sciences
Fan Liu, Lei Zhang, Chongyang Zhang, Ziguang Chen, Jingguang Li
Summary: NO2 emissions from wall-mounted gas stoves used for household heating have become a significant source of indoor pollution in Chinese urban areas. The high indoor concentration of NO2 poses potential health risks to residents. It is urgently necessary to establish relevant regulations and implement emission reduction technologies to reduce NO2 emissions from wall-mounted gas stoves.
SCIENCE OF THE TOTAL ENVIRONMENT
(2024)
Letter
Environmental Sciences
Hans Peter H. Arp, Raoul Wolf, Sarah E. Hale, Sivani Baskaran, Juliane Gluege, Martin Scheringer, Xenia Trier, Ian T. Cousins, Harrie Timmer, Roberta Hofman-Caris, Anna Lennquist, Andre D. Bannink, Gerard J. Stroomberg, Rosa M. A. Sjerps, Rosa Montes, Rosario Rodil, Jose Benito Quintana, Daniel Zahn, Herve Gallard, Tobias Mohr, Ivo Schliebner, Michael Neumann
SCIENCE OF THE TOTAL ENVIRONMENT
(2024)
Article
Environmental Sciences
Philomina Onyedikachi Peter, Binessi Edouard Ifon, Francois Nkinahamira, Kayode Hassan Lasisi, Jiangwei Li, Anyi Hu, Chang-Ping Yu
Summary: This study investigates the relationship between dissolved organic matter (DOM) and Rare Earth Elements (REEs) in sediments from Yundang Lagoon, China. The results show four distinct fluorescent components, with protein-like substances being the most prevalent. Additionally, the total fluorescence intensity and LREE concentrations exhibit a synchronized increase from Outer to Inner to Songbai Lake core sediments. The findings demonstrate a strong correlation between DOM content and pollution levels.
SCIENCE OF THE TOTAL ENVIRONMENT
(2024)
Article
Environmental Sciences
Surya Gupta, Pasquale Borrelli, Panos Panagos, Christine Alewell
Summary: The objective of this study is to incorporate soil hydraulic properties into the erodibility factor (K) of USLE-type models. By modifying and improving the existing equations for soil texture and permeability, the study successfully included information on saturated hydraulic conductivity (Ksat) into the calculation of K factor. Using the Random Forest machine learning algorithm, two independent K factor maps with different spatial resolutions were generated. The results show that the decrease in K factor values has a positive impact on the modeling of soil erosion rates.
SCIENCE OF THE TOTAL ENVIRONMENT
(2024)
Article
Environmental Sciences
Jesmin Akter, Wendy J. M. Smith, Yawen Liu, Ilho Kim, Stuart L. Simpson, Phong Thai, Asja Korajkic, Warish Ahmed
Summary: The choice of workflow in wastewater surveillance has a significant impact on SARS-CoV-2 concentrations, while having minimal effects on HF183 and no effect on HAdV 40/41 concentrations. Certain components in the workflow can be interchangeable, but factors such as buffer type, chloroform, and homogenization speed can affect the recovery of viruses and bacteria.
SCIENCE OF THE TOTAL ENVIRONMENT
(2024)
Article
Environmental Sciences
Yu Luo, Xueting Yang, Diwei Wang, Hongmei Xu, Hongai Zhang, Shasha Huang, Qiyuan Wang, Ningning Zhang, Junji Cao, Zhenxing Shen
Summary: Atmospheric PM2.5, which can generate reactive oxygen species (ROS), is associated with cardiorespiratory morbidity and mortality. The study found that both the mass concentration of PM2.5 and the DTT activity were higher during the heating season than during the nonheating season. Combustion sources were the primary contributors to DTT activity during the heating season, while secondary formation dominated during the nonheating season. The study also revealed that biomass burning had the highest inherent oxidation potential among all sources investigated.
SCIENCE OF THE TOTAL ENVIRONMENT
(2024)
Article
Environmental Sciences
Erin L. Murphy, Leah R. Gerber, Chelsea M. Rochman, Beth Polidoro
Summary: Plastic pollution has devastating consequences for marine organisms. This study uses a trait-based framework to develop a vulnerability index for marine mammals, seabirds, and sea turtles in Hawai'i. The index ranks 63 study species based on their vulnerability to macroplastic pollution, providing valuable information for species monitoring and management priorities.
SCIENCE OF THE TOTAL ENVIRONMENT
(2024)
Article
Environmental Sciences
Kenji Maurice, Amelia Bourceret, Sami Youssef, Stephane Boivin, Liam Laurent-Webb, Coraline Damasio, Hassan Boukcim, Marc-Andre Selosse, Marc Ducousso
Summary: Growing pressure from climate change and agricultural land use is destabilizing soil microbial community interactions. Little is known about microbial community resistance and adaptation to disturbances, hindering our understanding of recovery latency and implications for ecosystem functioning. This study found that anthropic disturbance and natural disturbance have different effects on the topology and stability of soil microbial networks.
SCIENCE OF THE TOTAL ENVIRONMENT
(2024)
Article
Environmental Sciences
Yunhao Li, Yali Feng, Haoran Li, Yisong Yao, Chenglong Xu, Jinrong Ju, Ruiyu Ma, Haoyu Wang, Shiwei Jiang
Summary: Deep-sea mining poses a serious threat to marine ecosystems and human health by disturbing sediment and transmitting metal ions through the food chain. This study developed a new regenerative adsorption material, OMN@SA, which effectively removes metal ions. The adsorption mechanism and performance of the material for metal ion fixation were investigated.
SCIENCE OF THE TOTAL ENVIRONMENT
(2024)
Article
Environmental Sciences
Antonio Medici, Margherita Lavorgna, Marina Isidori, Chiara Russo, Elena Orlo, Giovanni Luongo, Giovanni Di Fabio, Armando Zarrelli
Summary: Valsartan, a widely used antihypertensive drug, has been detected in high concentrations in surface waters due to its unchanged excretion and incomplete degradation in wastewater treatment plants. This study investigated the degradation of valsartan and identified 14 degradation byproducts. The acute and chronic toxicity of these byproducts were evaluated in key organisms in the freshwater trophic chain.
SCIENCE OF THE TOTAL ENVIRONMENT
(2024)
Article
Environmental Sciences
Jiang Lin, Lianbao Chi, Qing Yuan, Busu Li, Mingbao Feng
Summary: This study investigated the photodegradation behavior and product formation of two representative pharmaceuticals in simulated estuary water. The study found that the formed transformation products of these pharmaceuticals have potential toxicity on marine organisms, including oxidative stress and damage to cellular components.
SCIENCE OF THE TOTAL ENVIRONMENT
(2024)
Article
Environmental Sciences
Hua Fang, Dongdong Jiang, Ye He, Siyi Wu, Yuehong Li, Ziqi Zhang, Haoting Chen, Zixin Zheng, Yan Sun, Wenxiang Wang
Summary: This study revealed that exposure to lower levels of air pollutants led to decreased pregnancy rates, with PM10, NO2, SO2, and CO emerging as the four most prominent pollutants. Individuals aged 35 and above exhibited heightened susceptibility to pollutants.
SCIENCE OF THE TOTAL ENVIRONMENT
(2024)
Article
Environmental Sciences
Ali Shaan Manzoor Ghumman, Rashid Shamsuddin, Amin Abbasi, Mohaira Ahmad, Yoshiaki Yoshida, Abdul Sami, Hamad Almohamadi
Summary: In this study, inverse vulcanized polysulfides (IVP) were synthesized by reacting molten sulfur with 4-vinyl benzyl chloride, and then functionalized using N-methyl D-glucamine (NMDG). The functionalized IVP showed a high mercury adsorption capacity and a machine learning model was developed to predict the amount of mercury removed. Furthermore, the functionalized IVP can be regenerated and reused, providing a sustainable and cost-effective adsorbent.
SCIENCE OF THE TOTAL ENVIRONMENT
(2024)
Article
Environmental Sciences
Rita Bonfiglio, Renata Sisto, Stefano Casciardi, Valeria Palumbo, Maria Paola Scioli, Erica Giacobbi, Francesca Servadei, Gerry Melino, Alessandro Mauriello, Manuel Scimeca
Summary: This study investigated the presence of aluminum in human colon cancer samples and its potential association with biological processes involved in cancer progression. Aluminum was found in tumor areas of 24% of patients and was associated with epithelial to mesenchymal transition (EMT) and cell death. Additional analyses revealed higher tumor mutational burden and mutations in genes related to EMT and apoptosis in aluminum-positive colon cancers. Understanding the molecular mechanisms of aluminum toxicity may improve strategies for the management of colon cancer patients.
SCIENCE OF THE TOTAL ENVIRONMENT
(2024)