Feedback-controlled microbubble generator producing 1 × 106 monodisperse bubbles per second

Foam-free monodisperse lipid-coated ultrasound contrast agent synthesis by flow-focusing through multi-gas-component microbubble stabilization

(2020) Tim Segers et al.   APPLIED PHYSICS LETTERS

Closed-loop feedback control of microbubble diameter from a flow-focusing microfluidic device

(2020) Yanjun Xie et al.   Biomicrofluidics

Three Decades of Ultrasound Contrast Agents: A Review of the Past, Present and Future Improvements

(2020) Peter Frinking et al.   ULTRASOUND IN MEDICINE AND BIOLOGY

Microbubble Agents: New Directions

(2020) Eleanor Stride et al.   ULTRASOUND IN MEDICINE AND BIOLOGY

Laminar hydrodynamic and thermal entrance lengths for simultaneously hydrodynamically and thermally developing forced and mixed convective flows in horizontal tubes

(2020) Marilize Everts et al.   EXPERIMENTAL THERMAL AND FLUID SCIENCE

High-throughput microfluidics for evaluating microbubble enhanced delivery of cancer therapeutics in spheroid cultures

(2020) Matthew D. Bourn et al.   JOURNAL OF CONTROLLED RELEASE

Ultrasound Contrast Agent Modeling: A Review

(2020) Michel Versluis et al.   ULTRASOUND IN MEDICINE AND BIOLOGY

Monodisperse versus Polydisperse Ultrasound Contrast Agents: In Vivo Sensitivity and safety in Rat and Pig

(2020) Alexandre Helbert et al.   ULTRASOUND IN MEDICINE AND BIOLOGY

The role of ultrasound-driven microbubble dynamics in drug delivery: from microbubble fundamentals to clinical translation

(2019) Silke Roovers et al.   LANGMUIR

Evaporation of Dilute Sodium Dodecyl Sulfate Droplets on a Hydrophobic Substrate

(2019) Wojciech Kwieciński et al.   LANGMUIR

Imaging Methods for Ultrasound Contrast Agents

(2019) Michalakis A. Averkiou et al.   ULTRASOUND IN MEDICINE AND BIOLOGY

Monodisperse Versus Polydisperse Ultrasound Contrast Agents: Non-Linear Response, Sensitivity, and Deep Tissue Imaging Potential

(2018) Tim Segers et al.   ULTRASOUND IN MEDICINE AND BIOLOGY

A flow focusing microfluidic device with an integrated Coulter particle counter for production, counting and size characterization of monodisperse microbubbles

(2018) J. M. Robert Rickel et al.   LAB ON A CHIP

Improving Sensitivity in Ultrasound Molecular Imaging by Tailoring Contrast Agent Size Distribution: In Vivo Studies

(2018) Jason E. Streeter et al.   Molecular Imaging

Reverse engineering the ultrasound contrast agent

(2018) Mark A. Borden et al.   ADVANCES IN COLLOID AND INTERFACE SCIENCE

From chip-in-a-lab to lab-on-a-chip: a portable Coulter counter using a modular platform

(2018) Stefan Dekker et al.   Microsystems & Nanoengineering

Image-based feedback and analysis system for digital microfluidics

(2017) Philippe Q. N. Vo et al.   LAB ON A CHIP

Universal Equations for the Coalescence Probability and Long-Term Size Stability of Phospholipid-Coated Monodisperse Microbubbles Formed by Flow Focusing

(2017) Tim Segers et al.   LANGMUIR

Uniform scattering and attenuation of acoustically sorted ultrasound contrast agents: Modeling and experiments

(2016) Tim Segers et al.   JOURNAL OF THE ACOUSTICAL SOCIETY OF AMERICA

On-chip preparation of nanoscale contrast agents towards high-resolution ultrasound imaging

(2016) Sally A. Peyman et al.   LAB ON A CHIP

Stability of Monodisperse Phospholipid-Coated Microbubbles Formed by Flow-Focusing at High Production Rates

(2016) Tim Segers et al.   LANGMUIR

Biophysical insight into mechanisms of sonoporation

(2016) Brandon Helfield et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Ultrasound molecular imaging: Moving toward clinical translation

(2015) Lotfi Abou-Elkacem et al.   EUROPEAN JOURNAL OF RADIOLOGY

Focused ultrasound-mediated drug delivery through the blood–brain barrier

(2015) Alison Burgess et al.   Expert Review of Neurotherapeutics

Single Cell Electrical Characterization Techniques

(2015) Muhammad Mansor et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Bubble sorting in pinched microchannels for ultrasound contrast agent enrichment

(2015) Maarten P. Kok et al.   LAB ON A CHIP

Closed-loop feedback control of droplet formation in a T-junction microdroplet generator

(2015) Wen Zeng et al.   SENSORS AND ACTUATORS A-PHYSICAL

Theranostic mRNA-loaded Microbubbles in the Lymphatics of Dogs: Implications for Drug Delivery

(2015) Heleen Dewitte et al.   Theranostics

Focused ultrasound-mediated drug delivery through the blood–brain barrier

(2015) Alison Burgess et al.   Expert Review of Neurotherapeutics

Acoustic behavior of microbubbles and implications for drug delivery

(2014) Klazina Kooiman et al.   ADVANCED DRUG DELIVERY REVIEWS

Acoustic investigation of pressure-dependent resonance and shell elasticity of lipid-coated monodisperse microbubbles

(2014) Yanjun Gong et al.   APPLIED PHYSICS LETTERS

Acoustic characterization of monodisperse lipid-coated microbubbles: Relationship between size and shell viscoelastic properties

(2014) Miguel A. Parrales et al.   JOURNAL OF THE ACOUSTICAL SOCIETY OF AMERICA

Acoustic bubble sorting for ultrasound contrast agent enrichment

(2014) Tim Segers et al.   LAB ON A CHIP

Microfluidic Chip with Integrated Electrical Cell-Impedance Sensing for Monitoring Single Cancer Cell Migration in Three-Dimensional Matrixes

(2013) Tien Anh Nguyen et al.   ANALYTICAL CHEMISTRY

Flow-focusing regimes for accelerated production of monodisperse drug-loadable microbubbles toward clinical-scale applications

(2013) Roger Shih et al.   LAB ON A CHIP

Ultrasound-Targeted Microbubble Destruction to Deliver siRNA Cancer Therapy

(2012) A. R. Carson et al.   CANCER RESEARCH

A microfluidic-based bubble generation platform enables analysis of physical property change in phospholipid surfactant layers by interfacial ozone reaction

(2012) Young Shik Shin et al.   LAB ON A CHIP

Expanding 3D geometry for enhanced on-chip microbubble production and single step formation of liposome modified microbubbles

(2012) Sally A. Peyman et al.   LAB ON A CHIP

Microbubble generation in a co-flow device operated in a new regime

(2011) Elena Castro-Hernández et al.   LAB ON A CHIP

Acoustically Bound Microfluidic Bubble Crystals

(2011) David Rabaud et al.   PHYSICAL REVIEW LETTERS

Microfluidic device incorporating closed loop feedback control for uniform and tunable production of micro-droplets

(2010) Erik Miller et al.   LAB ON A CHIP

A feedback control system for high-fidelity digital microfluidics

(2010) Steve C. C. Shih et al.   LAB ON A CHIP

Transcranial ultrasound in clinical sonothrombolysis (TUCSON) trial

(2009) Carlos A. Molina et al.   ANNALS OF NEUROLOGY

Microbubbles in ultrasound-triggered drug and gene delivery

(2008) Sophie Hernot et al.   ADVANCED DRUG DELIVERY REVIEWS

High-speed particle detection in a micro-Coulter counter with two-dimensional adjustable aperture

(2008) Romen Rodriguez-Trujillo et al.   BIOSENSORS & BIOELECTRONICS

Microbubble size isolation by differential centrifugation

(2008) Jameel A. Feshitan et al.   JOURNAL OF COLLOID AND INTERFACE SCIENCE

All-electronic droplet generation on-chip with real-time feedback control for EWOD digital microfluidics

(2008) Jian Gong et al.   LAB ON A CHIP

Maintaining Monodispersity in a Microbubble Population Formed by Flow-Focusing

(2008) Esra Talu et al.   LANGMUIR

Pressure-Dependent Attenuation and Scattering of Phospholipid-Coated Microbubbles at Low Acoustic Pressures

(2008) Marcia Emmer et al.   ULTRASOUND IN MEDICINE AND BIOLOGY