Transcriptional profiling of the mouse hippocampus supports an NMDAR-mediated neurotoxic mode of action for benzo[a]pyrene

Tissue-specific in vivo genetic toxicity of nine polycyclic aromatic hydrocarbons assessed using the Muta™Mouse transgenic rodent assay

(2016) Alexandra S. Long et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY

The impact of p53 on DNA damage and metabolic activation of the environmental carcinogen benzo[a]pyrene: effects in Trp53(+/+), Trp53(+/–) and Trp53(−/−) mice

(2015) Annette M. Krais et al.   ARCHIVES OF TOXICOLOGY

Determination of 3-OHB[a]P and (+)-anti-BPDE in Rats Blood and Brain Tissue of B[a]P Exposure by HPLC with Fluorescence Detection

(2015) Xiao-Chen Liu et al.   CHROMATOGRAPHIA

Comparison of toxicogenomics and traditional approaches to inform mode of action and points of departure in human health risk assessment of benzo[a]pyrene in drinking water

(2015) Ivy Moffat et al.   CRITICAL REVIEWS IN TOXICOLOGY

Prenatal exposure to polycyclic aromatic hydrocarbons/aromatics, BDNF and child development

(2015) Frederica Perera et al.   ENVIRONMENTAL RESEARCH

Neurotoxicity may be an overlooked consequence of benzo[a]pyrene exposure that is relevant to human health risk assessment

(2015) Nikolai L. Chepelev et al.   MUTATION RESEARCH-REVIEWS IN MUTATION RESEARCH

Pulmonary Inflammation Impacts on CYP1A1-Mediated Respiratory Tract DNA Damage Induced by the Carcinogenic Air Pollutant Benzo[a]pyrene

(2015) Volker M. Arlt et al.   TOXICOLOGICAL SCIENCES

Impact of Genomics Platform and Statistical Filtering on Transcriptional Benchmark Doses (BMD) and Multiple Approaches for Selection of Chemical Point of Departure (PoD)

(2015) A. Francina Webster et al.   PLoS One

HTSeq--a Python framework to work with high-throughput sequencing data

(2014) S. Anders et al.   BIOINFORMATICS

Long-term exposure to low-concentrations of Cr(VI) induce DNA damage and disrupt the transcriptional response to benzo[a]pyrene

(2014) Jerald L. Ovesen et al.   TOXICOLOGY

Animal models of brain maldevelopment induced by cycad plant genotoxins

(2013) Glen E. Kisby et al.   BIRTH DEFECTS RESEARCH PART C-EMBRYO TODAY-REVIEWS

Transcriptomic responses generated by hepatocarcinogens in a battery of liver-based in vitro models

(2013) Tatyana Y. Doktorova et al.   CARCINOGENESIS

Neurotoxic effect of subacute benzo(a)pyrene exposure on gene and protein expression in Sprague-Dawley rats

(2013) Shu-qun Cheng et al.   ENVIRONMENTAL TOXICOLOGY AND PHARMACOLOGY

Hepatic genotoxicity and toxicogenomic responses in Muta™Mouse males treated with dibenz[a,h]anthracene

(2013) Amal I. Malik et al.   MUTAGENESIS

Tau Hyperphosphorylation is Associated with Spatial Learning and Memory After Exposure to Benzo[a]pyrene in SD Rats

(2013) Jisheng Nie et al.   NEUROTOXICITY RESEARCH

Case study on the utility of hepatic global gene expression profiling in the risk assessment of the carcinogen furan

(2013) Anna Francina Jackson et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY

STAR: ultrafast universal RNA-seq aligner

(2012) Alexander Dobin et al.   BIOINFORMATICS

Subchronic Oral Exposure to Benzo(a)pyrene Leads to Distinct Transcriptomic Changes in the Lungs That Are Related to Carcinogenesis

(2012) Sarah Labib et al.   TOXICOLOGICAL SCIENCES

Benzo[α]pyrene-Induced Anti-Depressive-like Behaviour in Adult Female Mice: Role of Monoaminergic Systems

(2011) Jaouad Bouayed et al.   BASIC & CLINICAL PHARMACOLOGY & TOXICOLOGY

Polycyclic Aromatic Hydrocarbons–Aromatic DNA Adducts in Cord Blood and Behavior Scores in New York City Children

(2011) Frederica P. Perera et al.   ENVIRONMENTAL HEALTH PERSPECTIVES

Critical windows of exposure for arsenic-associated impairment of cognitive function in pre-school girls and boys: a population-based cohort study

(2011) J. Hamadani et al.   INTERNATIONAL JOURNAL OF EPIDEMIOLOGY

The Cycad Genotoxin MAM Modulates Brain Cellular Pathways Involved in Neurodegenerative Disease and Cancer in a DNA Damage-Linked Manner

(2011) Glen E. Kisby et al.   PLoS One

Early Postnatal Benzo(a)pyrene Exposure in Sprague-Dawley Rats Causes Persistent Neurobehavioral Impairments that Emerge Postnatally and Continue into Adolescence and Adulthood

(2011) Chengzhi Chen et al.   TOXICOLOGICAL SCIENCES

Pulmonary gene and microRNA expression changes in mice exposed to benzo(a)pyrene by oral gavage

(2011) Sabina Halappanavar et al.   TOXICOLOGY

Effects of subchronic benzo(a)pyrene exposure on neurotransmitter receptor gene expression in the rats hippocampus related with spatial learning and memory change

(2011) Chongying Qiu et al.   TOXICOLOGY

Ontology-Based Meta-Analysis of Global Collections of High-Throughput Public Data

(2010) Ilya Kupershmidt et al.   PLoS One

Application of Transcriptional Benchmark Dose Values in Quantitative Cancer and Noncancer Risk Assessment

(2010) Russell S. Thomas et al.   TOXICOLOGICAL SCIENCES

A scaling normalization method for differential expression analysis of RNA-seq data

(2010) Mark D Robinson et al.   GENOME BIOLOGY

edgeR: a Bioconductor package for differential expression analysis of digital gene expression data

(2009) M. D. Robinson et al.   BIOINFORMATICS

DNA repair modulates the vulnerability of the developing brain to alkylating agents

(2009) G.E. Kisby et al.   DNA REPAIR

Knockdown of the aryl hydrocarbon receptor attenuates excitotoxicity and enhances NMDA-induced BDNF expression in cortical neurons

(2009) Chun-Hua Lin et al.   JOURNAL OF NEUROCHEMISTRY

Control of Cognition and Adaptive Behavior by the GLP/G9a Epigenetic Suppressor Complex

(2009) Anne Schaefer et al.   NEURON

Prenatal Airborne Polycyclic Aromatic Hydrocarbon Exposure and Child IQ at Age 5 Years

(2009) F. P. Perera et al.   PEDIATRICS

Sub-acute administration of benzo[a]pyrene (B[a]P) reduces anxiety-related behaviour in adult mice and modulates regional expression of N-methyl-d-aspartate (NMDA) receptors genes in relevant brain regions

(2008) Nathalie Grova et al.   CHEMOSPHERE

Estrogenic activity of environmental polycyclic aromatic hydrocarbons in uterus of immature Wistar rats

(2008) Vladimír Kummer et al.   TOXICOLOGY LETTERS