4.8 Article

Coupled near-field and far-field exposure assessment framework for chemicals in consumer products

Journal

ENVIRONMENT INTERNATIONAL
Volume 94, Issue -, Pages 508-518

Publisher

PERGAMON-ELSEVIER SCIENCE LTD
DOI: 10.1016/j.envint.2016.06.010

Keywords

Near-field consumer exposure; Multimedia multi-pathway framework; Product intake fraction; Life cycle impact assessment; Chemical alternatives assessment; High-throughput risk screening

Funding

  1. European Commission under the Seventh Framework Programme [631910, 285286]
  2. U.S. EPA on Development of Modular Risk Pathway Descriptions for Life Cycle Assessment [EP-14-C-000115]
  3. Long Range Research Initiative of the American Chemistry Council [MTH1001-01]
  4. U.S. Department of Energy [DW-89-92298301]
  5. U.S. EPA [DW-89-92298301]

Ask authors/readers for more resources

Humans can be exposed to chemicals in consumer products through product use and environmental emissions over the product life cycle. Exposure pathways are often complex, where chemicals can transfer directly from products to humans during use or exchange between various indoor and outdoor compartments until sub-fractions reach humans. To consistently evaluate exposure pathways along product life cycles, a flexible mass balance-based assessment framework is presented structuring multimedia chemical transfers in a matrix of direct inter-compartmental transfer fractions. By matrix inversion, we quantify cumulative multimedia transfer fractions and exposure pathway-specific product intake fractions defined as chemical mass taken in by humans per unit mass of chemical in a product. Combining product intake fractions with chemical mass in the product yields intake estimates for use in life cycle impact assessment and chemical alternatives assessment, or daily intake doses for use in risk-based assessment and high-throughput screening. Two illustrative examples of chemicals used in personal care products and flooring materials demonstrate how this matrix-based framework offers a consistent and efficient way to rapidly compare exposure pathways for adult and child users and for the general population. This framework constitutes a user-friendly approach to develop, compare and interpret multiple human exposure scenarios in a coupled system of near-field ('user' environment), far-field and human intake compartments, and helps understand the contribution of individual pathways to overall human exposure in various product application contexts to inform decisions in different science-policy fields for which exposure quantification is relevant (C) 2016 The Authors. Published by Elsevier Ltd.

Authors

I am an author on this paper
Click your name to claim this paper and add it to your profile.

Reviews

Primary Rating

4.8
Not enough ratings

Secondary Ratings

Novelty
-
Significance
-
Scientific rigor
-
Rate this paper

Recommended

Article Construction & Building Technology

A life cycle approach to indoor air quality in designing sustainable buildings: Human health impacts of three inner and outer insulations

Alice Maury-Micolier, Lei Huang, Franck Taillandier, Guido Sonnemann, Olivier Jolliet

Summary: This paper develops a Life Cycle Assessment-based methodology to assess and compare the burden shifting between indoor air quality and energy consumption, as well as between the building construction and use stages, focusing on three insulation materials. The study finds that human health damage due to indoor exposure is dominant and substantial, except for extruded polystyrene, due to its high global warming potential. The total damages on human health depend on building materials production, emissions during use stage, and impacts related to energy load, and can be minimized with specific insulation thickness and air renewal rate.

BUILDING AND ENVIRONMENT (2023)

Article Environmental Sciences

Ecotoxicity characterization of chemicals: Global recommendations and implementation in USEtox

Mikolaj Owsianiak, Michael Z. Hauschild, Leo Posthuma, Erwan Saouter, Martina G. Vijver, Thomas Backhaus, Melanie Douziech, Tamar Schlekat, Peter Fantke

Summary: This study advances the characterization of ecotoxicity in life cycle impact assessment by proposing recommendations based on international expert workshops and work conducted under the UNEP-SETAC Life Cycle Initiative in the GLAM project. The study includes specific recommendations for expanding the assessment scope by introducing additional environmental compartments and utilizing chronic test data. The researchers propose a mathematical framework for calculating freshwater ecotoxicity characterization factors and apply it to a life cycle assessment case study on rice production and consumption. The results highlight the need for careful interpretation of life cycle assessment scores in consideration of species sensitivity distributions.

CHEMOSPHERE (2023)

Review Environmental Sciences

Linking freshwater ecotoxicity to damage on ecosystem services in life cycle assessment

Susan A. Oginah, Leo Posthuma, Lorraine Maltby, Michael Hauschild, Peter Fantke

Summary: Freshwater ecosystems face threats from chemical pollution, and there is a need for mechanistic models and frameworks to translate ecotoxicity data into damage on species diversity, functional diversity, and ecosystem services. This paper proposes an evaluation of available approaches to characterize the damage of chemical pollution on freshwater ecosystem services, and presents possible stepwise approaches to link ecotoxicity effects to species loss, functional diversity loss, and damage on ecosystem services. Harmonization of assumptions and boundary conditions is needed to integrate this pathway into life cycle assessment and other comparative frameworks.

ENVIRONMENT INTERNATIONAL (2023)

Editorial Material Environmental Sciences

Advancing exposure knowledge and its uptake into policy: The European exposure science strategy 2020-2030 (Special Issue)

Peter Fantke, Natalie von Goetz, Matti Jantunen

ENVIRONMENT INTERNATIONAL (2023)

Article Environmental Sciences

Comparative selective pressure potential of antibiotics in the environment

Yasmine Emara, Olivier Jolliet, Matthias Finkbeiner, Stefanie Hess, Marissa Kosnik, Peter Fantke

Summary: To guide environmental and public health policies, it is important to assess antibiotic resistance selection pressure under measured environmental concentrations (MECs) and compare mitigation strategies. This study aims to derive minimum selective concentrations (MSCs) and species sensitivity distributions (SSDs) for different antibiotics. The results highlight specific environmental compartments and antibiotics that should be examined for their role in resistance dissemination.

ENVIRONMENTAL POLLUTION (2023)

Article Environmental Sciences

Generating environmental sampling and testing data for micro- and nanoplastics for use in life cycle impact assessment

Cecilia Askham, Valentina H. Pauna, Anne-Marie Boulay, Peter Fantke, Olivier Jolliet, Jerome Lavoie, Andy M. Booth, Claire Coutris, Francesca Verones, Miriam Weber, Martina G. Vijver, Amy Lusher, Carla Hajjar

Summary: Current efforts focus on quantifying and describing the magnitude of plastic pollution and its impacts on human and environmental health. This study examines existing approaches for gathering and reporting data on micro-and nanoplastics (MNPs) exposure and effects in order to improve the integration of this data into Life Cycle Assessment (LCA). The outcomes suggest the need for improved data collection, validation, and reporting, and propose a set of requirements for increasing the potential use of receptor-oriented studies in LCA.

SCIENCE OF THE TOTAL ENVIRONMENT (2023)

Article Toxicology

Modernizing persistence-bioaccumulation-toxicity (PBT) assessment with high throughput animal-free methods

Beate I. Escher, Rolf Altenburger, Matthias Blueher, John K. Colbourne, Ralf Ebinghaus, Peter Fantke, Michaela Hein, Wolfgang Koeck, Klaus Kuemmerer, Sina Leipold, Xiaojing Li, Martin Scheringer, Stefan Scholz, Michael Schloter, Pia-Johanna Schweizer, Tamara Tal, Igor Tetko, Claudia Traidl-Hoffmann, Lukas Y. Wick, Kathrin Fenner

Summary: The assessment of persistence, bioaccumulation, and toxicity is crucial for ensuring chemical safety and is a cornerstone of the EU's chemicals regulation. Existing methods for PBT assessment are complex, inaccurate, and rely on animal testing. New-approach methodologies propose innovative hazard indicators, CTE and PTE, which can be measured using high throughput in vitro bioassays.

ARCHIVES OF TOXICOLOGY (2023)

Article Environmental Sciences

Probabilistic Points of Departure and Reference Doses for Characterizing Human Noncancer and Developmental/Reproductive Effects for 10,145 Chemicals

Nicolo Aurisano, Olivier Jolliet, Weihsueh A. Chiu, Richard Judson, Suji Jang, Aswani Unnikrishnan, Marissa B. Kosnik, Peter Fantke

Summary: This study developed a semi-automated approach to determine surrogate oral route point of departure (POD) values and corresponding toxicity values for chemicals without regulatory assessments. By using data from the U.S. Environmental Protection Agency's Toxicity Value Database, the researchers were able to significantly expand the coverage of chemicals for risk assessment and management purposes.

ENVIRONMENTAL HEALTH PERSPECTIVES (2023)

Article Construction & Building Technology

Coupled mass and heat transfer modelling in building envelopes to consistently assess human exposure and energy performance in indoor environments

Alice Maury-Micolier, Lei Huang, Olivier Jolliet

Summary: We developed a numerical model to predict human exposure to pollutants and heating load by coupling heat and chemical transfers in the building envelope. Our study shows that temperature variation by season and location have a significant effect on chemical emission dynamics from building materials and human exposure. Increasing indoor temperature by 10 degrees C doubles the maximum indoor air concentration of VOCs and SVOCs from vinyl flooring, leading to a 50% increase in chemical intake by occupants. In 2050, due to climate change-induced temperature increase, occupants' exposure to SVOCs emission in Lille is likely to increase by 20%.

JOURNAL OF BUILDING PERFORMANCE SIMULATION (2023)

Article Construction & Building Technology

Integrated empirical and modelled determination of the human health impacts of building material VOCs

Rachna Bhoonah, Alice Maury-Micolier, Olivier Jolliet

BUILDING AND ENVIRONMENT (2023)

Article Engineering, Environmental

To Split or Not to Split: Characterizing Chemical Pollution Impacts in Aquatic Ecosystems with Species Sensitivity Distributions for Specific Taxonomic Groups

Susan Anyango Oginah, Leo Posthuma, Michael Hauschild, Jaap Slootweg, Marissa Kosnik, Peter Fantke

Summary: Bridging applied ecology and ecotoxicology is crucial for ecosystem protection. Splitting species sensitivity distributions (SSDs) can improve pollution impact assessments, especially for chemicals with specific modes of action and narcotic chemicals. This study provides a potential framework for using split SSDs in environmental protection, life cycle assessment, and freshwater ecosystem management, with significant implications for decision-support globally.

ENVIRONMENTAL SCIENCE & TECHNOLOGY (2023)

Article Engineering, Environmental

System Approach for Characterizing and Evaluating Factors for Occupational Health Impacts Due to Nonfatal Injuries and Illnesses for the Use in Life Cycle Assessment

Zhehan Huang, Gael Kijko, Kelly Scanlon, Shannon Lloyd, Andrew Henderson, Peter Fantke, Olivier Jolliet, Shaobin Li

Summary: This study proposes a system approach and new data set to characterize and evaluate occupational health impacts in work environments, aiming to improve the comprehensiveness of life cycle assessment methods. The study finds that the data set of characterization factors for occupational health impacts varies significantly by industry, indicating that occupational health impacts are concentrated in a small portion of industries. A case study demonstrates the feasibility and importance of incorporating occupational health impacts into life cycle impact assessment methods.

ENVIRONMENTAL SCIENCE & TECHNOLOGY (2023)

No Data Available