Article
Environmental Sciences
Daheng Yang, Xiaoqin Chen, Weidong Cao, Cheng Xu, Lin Chang, Guangfeng Long
Summary: Although the association between single PAHs exposure and telomere length has been studied, the relationship between mixed PAHs exposure and telomere length in the general population is still uncertain. This study analyzed 8 PAHs and their correlation with telomere length, finding that mixed PAHs exposure was negatively associated with telomere length. Specifically, 2-napthol and 2-fluorene concentrations showed a significant negative correlation with telomere length. These findings indicate that PAHs may have a negative impact on telomere length in the general population.
ENVIRONMENTAL SCIENCE AND POLLUTION RESEARCH
(2023)
Article
Environmental Sciences
Yan-Ling Deng, Pan Yang, Yi-Xin Wang, Chong Liu, Qiong Luo, Tian Shi, Jia-Yue Zeng, Ting-Ting Lu, Pan-Pan Chen, Yu Miao, Min Zhang, Fei-Peng Cui, Wen-Qing Lu, Qiang Zeng
Summary: Previous studies have found associations between exposure to phthalates and polycyclic aromatic hydrocarbons (PAHs) and altered semen quality, but no studies have evaluated their combined effects. This study aimed to investigate the associations between urinary metabolite mixtures of phthalates and PAHs and semen quality.
ENVIRONMENTAL SCIENCE AND POLLUTION RESEARCH
(2022)
Article
Environmental Sciences
Fang Wang, Yuying Wang, Yu Wang, Teng Jia, Li Chang, Jie Ding, Li Zhou
Summary: This study investigated the relationship between exposure to polycyclic aromatic hydrocarbons (PAHs) and hypertension, and found a positive dose-response relationship between high exposure to certain PAH metabolites and the risk of hypertension. Obese individuals with high PAH exposure were at greater risk for hypertension than individuals with low PAH exposure and normal BMI.
ENVIRONMENTAL SCIENCE AND POLLUTION RESEARCH
(2022)
Article
Environmental Sciences
Manthar Ali Mallah, Li Changxing, Mukhtiar Ali Mallah, Muhammad Naveed, Yang Liu, Sobia Noreen, He Xi, Wei Wang, Feifei Feng, Qiao Zhang
Summary: This study aimed to investigate the association between urinary PAHs and cardiovascular diseases. The results showed a positive correlation between urinary PAHs and the prevalence of coronary heart disease, angina, heart attack, and stroke.
ENVIRONMENTAL RESEARCH
(2022)
Article
Environmental Sciences
Boying Liu, Yanyan Chen, Siyao Li, Yuanyuan Xu, Yi Wang
Summary: Exposure to polycyclic aromatic hydrocarbons (PAHs) may increase the risk of thyroid nodular goiter (NG)/papillary thyroid carcinoma (PTC), with a gender-specific effect observed. Elevated concentrations of specific OH-PAHs in NG and PTC patients are associated with increased disease risk.
ENVIRONMENTAL POLLUTION
(2021)
Article
Endocrinology & Metabolism
Qiming Yuan, Kun Jin, Xianghong Zhou, Zhimei Qiu, Jiakun Li, Di Jin, Zilong Zhang, Chichen Zhang, Lu Yang, Yu Zhan, Shi Qiu, Qiang Wei
Summary: This study found that exposure to polycyclic aromatic hydrocarbons (PAHs) is associated with changes in levels of sexual hormones. Specifically, urinary 2-hydroxynapthalene and 3-hydroxyfluorene were associated with increased testosterone levels in males, while urinary 1-hydroxyphenanthrene was associated with increased estradiol levels in females.
FRONTIERS IN ENDOCRINOLOGY
(2022)
Article
Engineering, Environmental
Manthar Ali Mallah, Zhu Ying, Mukhtiar Ali, Junwei Guo, Feifei Feng, Wei Wang, Pingping Shang, Qiao Zhang
Summary: This study aims to examine the association between urinary polycyclic aromatic hydrocarbons (PAHs) and liver function parameters among the US population. Data from the National Health and Nutritional Examination Survey (NHANES) 2003-2016 were used, and a total of 2515 participants were included. Logistic regression analysis showed that increased 9-hydroxyfluorene was associated with elevated GGT levels. In conclusion, 9-hydroxyfluorene is associated with elevated GGT levels, and its effect is modified by other PAHs.
ENVIRONMENTAL GEOCHEMISTRY AND HEALTH
(2023)
Review
Genetics & Heredity
Anne-Julie Fattet, Maxime Chaillot, Isabelle Koscinski
Summary: Male factors are involved in around 50% of infertility cases, with up to 40% being diagnosed as idiopathic. It is important to evaluate additional biomarkers for sperm quality, especially considering the increasing use of ART and declining semen parameters. This systematic review selected studies on telomere length as a potential male fertility biomarker. The results suggest that shorter sperm telomeres may be associated with altered semen parameters or male infertility, but further studies are needed to determine its role in assessing individual fertility.
Article
Environmental Sciences
Xiaoran Duan, Hongmei Wang, Yongli Yang, Pengpeng Wang, Hui Zhang, Bin Liu, Wan Wei, Wu Yao, Xiaoshan Zhou, Jie Zhao, Wei Wang
Summary: This study suggests that exposure to polycyclic aromatic hydrocarbons (PAHs) in workers may lead to telomere shortening, while genetic variations in the TEP1 gene could affect telomere length. Specifically, carrying the TEP1 rs1760903 CC genotype may be protective against telomere shortening. These findings highlight the roles of environmental factors and genetic variations in telomere damage, providing a basis for early detection of susceptible populations and establishment of occupational standards.
ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY
(2021)
Article
Environmental Sciences
Bin Zhang, Lu Liu, Lan Guo, Shugang Guo, Xinyu Zhao, Gaisheng Liu, Qiang Li, Liuquan Jiang, Baolong Pan, Jisheng Nie, Jin Yang
Summary: This study found an association between PAHs exposure and abnormal glucose levels among coke-oven plant workers, with telomere length potentially mediating this relationship.
Article
Environmental Sciences
Esther M. John, Jocelyn Koo, Sue A. Ingles, Theresa H. Keegan, Jenny T. Nguyen, Catherine Thomsen, Mary Beth Terry, Regina M. Santella, Khue Nguyen, Beizhan Yan
Summary: Urinary PAH exposure was found to be widespread in girls aged 6-16 years, with concentrations varying by age, race/ethnicity, body mass index percentile, as well as outdoor, indoor, and dietary sources of exposure.
ENVIRONMENTAL RESEARCH
(2022)
Article
Environmental Sciences
Yan Lin, Xueyao Gao, Xinghua Qiu, Jinming Liu, Chi-Hong Tseng, Junfeng Jim Zhang, Jesus A. Araujo, Yifang Zhu
Summary: This study found that traveling from Los Angeles to Beijing led to significant increases in the concentrations of alkyl-naphthalene and alkyl-phenanthrene metabolites in urine samples, with different concentration ratios indicating relative exposure contributions from petrogenic and pyrogenic sources. These results suggest that 2-PHECA to hydroxy-phenanthrene ratio could be used as an index to reflect the sources of exposure to PAHs.
ENVIRONMENT INTERNATIONAL
(2021)
Article
Environmental Sciences
Mengmeng Fu, Huimin Wang, QianXiang Bai, Juanjuan Du, Qiao Niu, Jisheng Nie
Summary: This study investigated the relationship between polycyclic aromatic hydrocarbon (PAH) metabolites and mild cognitive impairment (MCI) in coke oven workers, and explored whether plasma p-tau231 can be used as a potential biomarker for MCI. The results showed that the urinary levels of PAH metabolites were positively associated with MCI and plasma p-tau231 levels in coke oven workers.
Article
Environmental Sciences
Zhiyu Yang, Shouyi Chen, Si Zhou, Conghui Xu, Chunxia Jing, Chongshan Guo, Xinhong Pan, Lixi Zeng, Lei Tan
Summary: This study evaluated the association between internal exposure to polycyclic aromatic hydrocarbons (PAHs) and urinary iodine concentration with thyroid volume in school-age children in Guangzhou, China. The results showed a significant positive association between urinary hydroxylated PAHs and thyroid volume. Additionally, urinary PAHs were also linked to urinary iodine, and iodine mediated the relationship between PAHs and thyroid volume.
ENVIRONMENTAL POLLUTION
(2023)
Article
Pharmacology & Pharmacy
Humairat H. Rahman, Danielle Niemann, Stuart H. Munson-McGee
Summary: This study found that urinary polycyclic aromatic hydrocarbons (PAHs) and metals were associated with an increased risk of emphysema in smokers, while certain arsenic species and metals showed an inverse relationship. Additionally, several demographic factors were significantly associated with emphysema in smokers.
TOXICOLOGY AND APPLIED PHARMACOLOGY
(2022)
Article
Ophthalmology
Min Ji, Qing Sun, Guowei Zhang, Zeyu Huang, Yujian Zhang, Qianyi Shen, Huaijin Guan
Summary: The study revealed that microglia-derived TNF-α plays a crucial role in regulating the activation of Muller cells during retinal neurodegeneration. TNF-α led to increased expression of GFAP and proinflammatory factors in Muller cells, while anti-TNFR1 and NF-κB inhibitor could reverse these changes.
EXPERIMENTAL EYE RESEARCH
(2022)
Article
Computer Science, Artificial Intelligence
Penghai Zhao, Weilan Wang, Guowei Zhang, Yuqi Lu
Summary: This study focuses on the binarization problem in degraded historical Tibetan document images and proposes an improved approach. By rescaling the input and output of the attention U-Net and accelerating the construction of the training set, the issue of pseudo-touching is successfully addressed, leading to better performance across several metrics.
NEURAL COMPUTING & APPLICATIONS
(2023)
Article
Engineering, Biomedical
Zhi-Sheng Ji, Gui-Bin Gao, Yan-Ming Ma, Jian-Xian Luo, Guo-Wei Zhang, Hua Yang, Nan Li, Qing-Yu He, Hong-Sheng Lin
Summary: A highly bioactive iridium complex was developed to treat spinal cord injuries, with enhanced antioxidative activities and improved therapeutic efficacy. The complex targets SOD1 and upregulates its expression to eliminate excess ROS production, protecting neuron cells from further damage and facilitating repair.
Article
Management
Guowei Zhang, Ning Jia, Ning Zhu, Yossiri Adulyasak, Shoufeng Ma
Summary: Assessing a humanitarian transportation network early after a disaster is crucial for reducing casualties. Drones are considered for the assessment operations due to their potential. However, a novel challenge arises in the drone arc routing problem where drones can travel off the road network. To address this challenge, a graph transformation technique and a robust team orienteering problem with uncertain assessment time are proposed. The problem is solved efficiently using path-based reformulation and Lagrangian decomposition, and an exact branch-and-price framework is applied.
EUROPEAN JOURNAL OF OPERATIONAL RESEARCH
(2023)
Article
Agronomy
Changqin Yang, Jianan Li, Guowei Zhang, Hongmei Shu, Xiaojing Wang, Wei Hu, Ruixian Liu
Summary: Straw returning combined with controlled-release nitrogen fertilizer (CRN) can significantly increase cotton yield, improve nitrogen utilization efficiency, and enhance soil quality. The combination of straw returning and a mixture of urea and CRN (UC) can promote biomass accumulation and nitrogen uptake, leading to higher nitrogen agronomic use efficiency and apparent recovery use efficiency.
Article
Mechanics
Guowei Zhang, Jianmin Ge
Summary: This study investigates a theoretical model of a simply supported curved plate structure in a temperature gradient by using modal superposition and temperature field analysis. The results of theoretical calculations are in good agreement with those obtained using finite element methods. The study also analyzes the acoustic radiation characteristics of the curved plate. The impact of temperature on the structure and acoustic properties is evaluated.
ARCHIVE OF APPLIED MECHANICS
(2022)
Article
Materials Science, Multidisciplinary
Dongya Yang, Jiajun Li, Gengrui Zhao, Honggang Wang, Zhenyu Li, Shengsheng Chen, Gui Gao, Guowei Zhang, Hong Xu
Summary: This study investigated the effects of molybdenum disilicide and ferrophosphorus particles on the tribological properties of copper-tin bismuth bimetallic bearing materials. The addition of these particles was found to improve the mechanical and wear resistance properties of the alloys.
MATERIALS SCIENCE AND TECHNOLOGY
(2023)
Article
Chemistry, Physical
Huan Yu, Guowei Zhang, Weize Lv, Hong Xu, Changjun Xu
Summary: An Al-7Si-Cu-Mg-Mn/steel bimetal was prepared by compound casting, and the effect of a coupled traveling and rotating magnetic field on the interface microstructure and shear strength was investigated. The magnetic field resulted in changes in the interface layer thickness, element concentration gradient, and dissolution rate of intermetallic compounds, leading to an increase in shear strength.
JOURNAL OF ALLOYS AND COMPOUNDS
(2023)
Article
Chemistry, Physical
Guowei Zhang, Zhaojie Wang, Changjun Xu, Hong Xu, Cong Wang
Summary: The age-hardening behavior of the Al-7Si-0.5Mg alloy was studied with different sizes and distributions of Si phase. The specimen with fine and homogeneous Si exhibited accelerated age-hardening kinetics and higher hardness compared to the specimen with coarse and clustered Si, attributed to the higher dislocation density caused by thermal contraction mismatch. The overlapping of the plastically-affected zone of adjacent Si in the specimen with large and clustered Si resulted in reduced volume fraction of the plastically-affected zone, lower dislocation density, and slower age-hardening kinetics. The relationship between Si radius and critical inter-particle spacing for minimizing interaction and maximizing dislocation density and age-hardening kinetics was established.
JOURNAL OF ALLOYS AND COMPOUNDS
(2023)
Article
Engineering, Multidisciplinary
Xiao Wang, Guowei Zhang, Yongqiang Li, Na Qu
Summary: This paper investigates the maintenance policy for a 2M1B assembly line system. By using an SMDP model and the HAMRL method, the learning process is accelerated and the maintenance strategy for the system is obtained. Empirical results show that the HAMRL algorithm has advantages in larger space and practical problems.
JOURNAL OF INDUSTRIAL AND MANAGEMENT OPTIMIZATION
(2023)
Article
Surgery
Yuehui Liang, Qinghong Jian, Ming-Gang Deng, Zongbi Yi, Chan Peng, Chunsheng Lu, Huan Yang, Jinyi Liu
Summary: This study evaluated lymph node ratio (LNR) as a predictor of postoperative radiotherapy (PORT) benefit in esophageal cancer patients. The results showed that LNR exceeding 0.23 was negatively associated with prognosis, and PORT was beneficial only in N1 stage with higher LNR.
ASIAN JOURNAL OF SURGERY
(2023)
Article
Obstetrics & Gynecology
Xi Ling, Haonan Cui, Qing Chen, Wang Yang, Peng Zou, Huan Yang, Niya Zhou, Jiuyang Deng, Jinyi Liu, Jia Cao, Lin Ao
Summary: This study investigates the association between sperm telomere length (STL) and sperm nuclear DNA damage and mitochondrial DNA abnormalities. The results show that STL is related to sperm nuclear DNA integrity and mitochondrial DNA abnormalities in healthy young college students.
HUMAN REPRODUCTION
(2023)
Review
Endocrinology & Metabolism
Mengchao He, Kun Liu, Jia Cao, Qing Chen
Summary: This review summarizes the current knowledge about the role and potential mechanisms of clock genes in regulating spermatogenesis. Rhythmic oscillation in semen parameters and physiological events of spermatogenesis have been observed. Disturbances in clock gene expression due to genetic mutations or environmental changes can significantly impair spermatogenesis, although the mechanisms of spermatogenesis regulation by clock genes remain unclear.
REVIEWS IN ENDOCRINE & METABOLIC DISORDERS
(2023)
Article
Environmental Sciences
Ying Guo, Qing Chen, Yu Zhan, Wenzheng Zhou, Haiyan Zhang, Niya Zhou, Huan Yang, Yi Chen, Yimeng Wang, Lei Sun, Lin Ao, Jinyi Liu, Wei Zhou, Hongbo Qi, Jia Cao
Summary: This study investigated the contribution of ambient air pollutants-induced semen damage to infertility risk by identifying the dose-response relationship between pollutants and semen parameters and susceptibility window. The results showed that multiple air pollutants, including SO2, O3, PMs, and NO2, were negatively associated with progressive motility, total motility, and sperm morphology. The analysis also revealed a mediating effect of sperm normal morphology in the association between SO2 and infertility. These findings suggest that air pollutants may affect semen quality and increase the risk of infertility.
SCIENCE OF THE TOTAL ENVIRONMENT
(2023)
Article
Ophthalmology
Lihua Kang, Jiawei Luo, Pengfei Li, Guowei Zhang, Miao Wei, Min Ji, Huaijin Guan
Summary: This study discovered that miR-125a-3p regulates apoptosis in LECs by suppressing TMBIM4, offering a new therapeutic target for cataract.
INTERNATIONAL OPHTHALMOLOGY
(2023)
