PTEN/AKT/mTOR pathway involvement in autophagy, mediated by miR-99a-3p and energy metabolism in ammonia-exposed chicken bursal lymphocytes

Ammonia inhalation-induced inflammation and structural impairment in the bursa of fabricius and thymus of broilers through NF-κB signaling pathway

(2020) Syed Waqas Ali Shah et al.   ENVIRONMENTAL SCIENCE AND POLLUTION RESEARCH

Cadmium exposure induces apoptosis, inflammation and immunosuppression through CYPs activation and antioxidant dysfunction in common carp neutrophils

(2020) Sun Jiaxin et al.   FISH & SHELLFISH IMMUNOLOGY

Chlorpyrifos induces the apoptosis and necroptosis of L8824 cells through the ROS/PTEN/PI3K/AKT axis

(2020) Lanqiao Wang et al.   JOURNAL OF HAZARDOUS MATERIALS

Whole transcriptome-based miRNA-mRNA network analysis revealed the mechanism of inflammation-immunosuppressive damage caused by cadmium in common carp spleens

(2020) Jianqing Chen et al.   SCIENCE OF THE TOTAL ENVIRONMENT

Mycoplasma gallisepticum Infection Impaired the Structural Integrity and Immune Function of Bursa of Fabricius in Chicken: Implication of Oxidative Stress and Apoptosis

(2020) Wei Zhang et al.   Frontiers in Veterinary Science

Ammonia-triggered apoptosis via immune function and metabolic process in the thymuses of chickens by proteomics analysis

(2020) Dechun Chen et al.   ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY

Baicalin attenuated Mycoplasma gallisepticum ‐induced immune impairment in the chicken Bursa of fabricius through modulation of autophagy and inhibited inflammation and apoptosis

(2020) Muhammad Ishfaq et al.   JOURNAL OF THE SCIENCE OF FOOD AND AGRICULTURE

NF-κB pathway took part in the development of apoptosis mediated by miR-15a and oxidative stress via mitochondrial pathway in ammonia-treated chicken splenic lymphocytes

(2020) Dechun Chen et al.   SCIENCE OF THE TOTAL ENVIRONMENT

Oxidative stress and mitochondrial dysfunction involved in ammonia-induced nephrocyte necroptosis in chickens

(2020) Qi Han et al.   ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY

Cadmium exposure induces pyroptosis of lymphocytes in carp pronephros and spleens by activating NLRP3

(2020) Yiming Zhang et al.   ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY

The involvement of miR-6615-5p/Smad7 axis and immune imbalance in ammonia-caused inflammatory injury via NF-κB pathway in broiler kidneys

(2020) Qi Han et al.   POULTRY SCIENCE

Mycoplasma gallisepticum infection triggered histopathological changes, oxidative stress and apoptosis in chicken thymus and spleen

(2020) Wanying Hu et al.   DEVELOPMENTAL AND COMPARATIVE IMMUNOLOGY

The effect of ammonia exposure on energy metabolism and mitochondrial dynamic proteins in chicken thymus: Through oxidative stress, apoptosis, and autophagy

(2020) Syed Waqas Ali Shah et al.   ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY

Ammonia exposure induced abnormal expression of cytokines and heat shock proteins via glucose metabolism disorders in chicken neutrophils

(2019) Dongxu Wang et al.   ENVIRONMENTAL SCIENCE AND POLLUTION RESEARCH

The evaluation of potential immunotoxicity induced by environmental pollutant ammonia in broilers

(2019) Yang An et al.   POULTRY SCIENCE

The co-expression of circRNA and mRNA in the thymuses of chickens exposed to ammonia

(2019) Dechun Chen et al.   ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY

Ammonia inhalation-mediated mir-202-5p leads to cardiac autophagy through PTEN/AKT/mTOR pathway

(2019) Houjuan Xing et al.   CHEMOSPHERE

Identification of signal pathways for immunotoxicity in the spleen of common carp exposed to chlorpyrifos

(2019) Houjuan Xing et al.   ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY

Antagonistic Effects Of Baicalin On Mycoplasma gallisepticum-Induced Inflammation And Apoptosis By Restoring Energy Metabolism In The Chicken Lungs

(2019) Muhammad Ishfaq et al.   Infection and Drug Resistance

Atmospheric H2S triggers immune damage by activating the TLR-7/MyD88/NF-κB pathway and NLRP3 inflammasome in broiler thymus

(2019) Xueyuan Hu et al.   CHEMOSPHERE

Ammonia inhalation impaired immune function and mitochondrial integrity in the broilers bursa of fabricius: Implication of oxidative stress and apoptosis

(2019) Syed Waqas Ali Shah et al.   ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY

The effect of Mycoplasma gallisepticum infection on energy metabolism in chicken lungs: Through oxidative stress and inflammation

(2019) Muhammad Ishfaq et al.   MICROBIAL PATHOGENESIS

Application of transcriptome analysis: Oxidative stress, inflammation and microtubule activity disorder caused by ammonia exposure may be the primary factors of intestinal microvilli deficiency in chicken

(2019) Shengchen Wang et al.   SCIENCE OF THE TOTAL ENVIRONMENT

miR-187-5p/apaf-1 axis was involved in oxidative stress-mediated apoptosis caused by ammonia via mitochondrial pathway in chicken livers

(2019) Yanmin Xu et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY

Alleviation Mechanisms of Selenium on Cadmium-Spiked in Chicken Ovarian Tissue: Perspectives from Autophagy and Energy Metabolism

(2018) Shuang Wang et al.   BIOLOGICAL TRACE ELEMENT RESEARCH

MiR-93-5p targeting PTEN regulates the NMDA-induced autophagy of retinal ganglion cells via AKT/mTOR pathway in glaucoma

(2018) Rui Li et al.   BIOMEDICINE & PHARMACOTHERAPY

Ammonia production in poultry houses can affect health of humans, birds, and the environment—techniques for its reduction during poultry production

(2018) Sadia Naseem et al.   ENVIRONMENTAL SCIENCE AND POLLUTION RESEARCH

MiR-181b regulates autophagy in a model of Parkinson’s disease by targeting the PTEN/Akt/mTOR signaling pathway

(2018) Wei Li et al.   NEUROSCIENCE LETTERS

Inhibitory effect of PXR on ammonia-induced hepatocyte autophagy via P53

(2018) Linlin Yan et al.   TOXICOLOGY LETTERS

miR-99a-5p acts as tumor suppressor via targeting to mTOR and enhances RAD001-induced apoptosis in human urinary bladder urothelial carcinoma cells

(2018) Te-Fu Tsai et al.   OncoTargets and Therapy

MicroRNA-202-5p functions as a tumor suppressor in colorectal carcinoma by directly targeting SMARCC1

(2018) Shao-Bo Ke et al.   GENE

Cadmium-mediated miR-30a-GRP78 leads to JNK-dependent autophagy in chicken kidney

(2018) Qunxiang Shi et al.   CHEMOSPHERE

Impaired Cellular Energy Metabolism Contributes to Duck-Enteritis-Virus-Induced Autophagy via the AMPK–TSC2–MTOR Signaling Pathway

(2017) Haichang Yin et al.   Frontiers in Cellular and Infection Microbiology

Ammonia emissions in Europe, part II: How ammonia emission abatement strategies affect secondary aerosols

(2016) Anna M. Backes et al.   ATMOSPHERIC ENVIRONMENT

High concentrations of atmospheric ammonia induce alterations of gene expression in the breast muscle of broilers (Gallus gallus) based on RNA-Seq

(2016) Bao Yi et al.   BMC GENOMICS

Autophagy and gap junctional intercellular communication inhibition are involved in cadmium-induced apoptosis in rat liver cells

(2015) Hui Zou et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Unique role for ATG5 in neutrophil-mediated immunopathology during M. tuberculosis infection

(2015) Jacqueline M. Kimmey et al.   NATURE

Proteome changes in the small intestinal mucosa of broilers (Gallus gallus) induced by high concentrations of atmospheric ammonia

(2015) Jize Zhang et al.   Proteome Science

MicroRNAs in Colorectal Neoplasia: From Pathobiology to Clinical Applications

(2014) Antonios Gargalionis et al.   CURRENT PHARMACEUTICAL BIOTECHNOLOGY

Overexpression of microRNA-99a attenuates heart remodelling and improves cardiac performance after myocardial infarction

(2014) Qiaoling Li et al.   JOURNAL OF CELLULAR AND MOLECULAR MEDICINE

Ammonia Drives Dendritic Cells into Dysfunction

(2014) C. Luo et al.   JOURNAL OF IMMUNOLOGY

Hexokinase-II Positively Regulates Glucose Starvation-Induced Autophagy through TORC1 Inhibition

(2014) David J. Roberts et al.   MOLECULAR CELL

Autophagy is essential for effector CD8+ T cell survival and memory formation

(2014) Xiaojin Xu et al.   NATURE IMMUNOLOGY

Inflammation and hepatic encephalopathy

(2013) Iona Coltart et al.   ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS

Cutting a fine figure

(2013) John Milton Lucocq et al.   Autophagy

Ammonia in the atmosphere: a review on emission sources, atmospheric chemistry and deposition on terrestrial bodies

(2013) Sailesh N. Behera et al.   ENVIRONMENTAL SCIENCE AND POLLUTION RESEARCH

Mst1 inhibits autophagy by promoting the interaction between Beclin1 and Bcl-2

(2013) Yasuhiro Maejima et al.   NATURE MEDICINE

Glucose induces autophagy under starvation conditions by a p38 MAPK-dependent pathway

(2012) Jose Félix Moruno-Manchón et al.   BIOCHEMICAL JOURNAL

Systemic inflammation and ammonia in hepatic encephalopathy

(2012) Thomas H. Tranah et al.   METABOLIC BRAIN DISEASE

AMPK and mTOR coordinate the regulation of Ulk1 and mammalian autophagy initiation

(2011) Libin Shang et al.   Autophagy

Autophagy facilitates glycolysis during Ras-mediated oncogenic transformation

(2010) Rebecca Lock et al.   MOLECULAR BIOLOGY OF THE CELL

Autophagy and the Integrated Stress Response

(2010) Guido Kroemer et al.   MOLECULAR CELL

Ammonia Derived from Glutaminolysis Is a Diffusible Regulator of Autophagy

(2010) C. H. Eng et al.   Science Signaling