Refolding and characterization of two G protein-coupled receptors purified from E. coli inclusion bodies

An online resource for GPCR structure determination and analysis

(2019) Christian Munk et al.   NATURE METHODS

Serial Femtosecond Crystallography of G Protein–Coupled Receptors

(2018) Benjamin Stauch et al.   Annual Review of Biophysics

Structural Connection between Activation Microswitch and Allosteric Sodium Site in GPCR Signaling

(2018) Kate L. White et al.   STRUCTURE

‘Crystal’ Clear? Lysophospholipid Receptor Structure Insights and Controversies

(2018) Victoria A. Blaho et al.   TRENDS IN PHARMACOLOGICAL SCIENCES

Successful Strategies to Determine High-Resolution Structures of GPCRs

(2016) Jin Xiang et al.   TRENDS IN PHARMACOLOGICAL SCIENCES

Methodological advances: the unsung heroes of the GPCR structural revolution

(2015) Eshan Ghosh et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Crystallizing membrane proteins for structure–function studies using lipidic mesophases

(2015) Martin Caffrey   BIOCHEMICAL SOCIETY TRANSACTIONS

The identification of GPR3 inverse agonist AF64394; The first small molecule inhibitor of GPR3 receptor function

(2014) Thomas Jensen et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Structure of signaling-competent neurotensin receptor 1 obtained by directed evolution inEscherichia coli

(2014) Pascal Egloff et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Modified T4 Lysozyme Fusion Proteins Facilitate G Protein-Coupled Receptor Crystallogenesis

(2014) Thor Seneca Thorsen et al.   STRUCTURE

Membrane protein structure determination — The next generation

(2013) Isabel Moraes et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES

Heterologous expression and purification of an active human TRPV3 ion channel

(2013) Stefan Kol et al.   FEBS Journal

Breaking the barriers in membrane protein crystallography

(2013) Hae Joo Kang et al.   INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY

The GPCR Network: a large-scale collaboration to determine human GPCR structure and function

(2012) Raymond C. Stevens et al.   NATURE REVIEWS DRUG DISCOVERY

Crystal Structure of a Lipid G Protein-Coupled Receptor

(2012) M. A. Hanson et al.   SCIENCE

Optimization of purification and refolding of the human chemokine receptor CXCR1 improves the stability of proteoliposomes for structure determination

(2011) Sang Ho Park et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES

Artificial membrane-like environments for in vitro studies of purified G-protein coupled receptors

(2011) Eugene Serebryany et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES

Development of an Automated High Throughput LCP-FRAP Assay to Guide Membrane Protein Crystallization in Lipid Mesophases

(2011) Fei Xu et al.   CRYSTAL GROWTH & DESIGN

GPCR stabilization using the bicelle-like architecture of mixed sterol-detergent micelles

(2011) Aaron A. Thompson et al.   METHODS

An efficient strategy for high throughput screening of recombinant integral membrane protein expression and stability

(2011) Junping Fan et al.   PROTEIN EXPRESSION AND PURIFICATION

Diversity and modularity of G protein-coupled receptor structures

(2011) Vsevolod Katritch et al.   TRENDS IN PHARMACOLOGICAL SCIENCES

Detergent binding explains anomalous SDS-PAGE migration of membrane proteins

(2009) Arianna Rath et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Expression, purification and in vitro functional reconstitution of the chemokine receptor CCR1

(2009) Samantha J. Allen et al.   PROTEIN EXPRESSION AND PURIFICATION

Overcoming the challenges of membrane protein crystallography

(2008) Elisabeth P Carpenter et al.   CURRENT OPINION IN STRUCTURAL BIOLOGY

Structural diversity of G protein-coupled receptors and significance for drug discovery

(2008) Malin C. Lagerström et al.   NATURE REVIEWS DRUG DISCOVERY

Microscale Fluorescent Thermal Stability Assay for Membrane Proteins

(2008) Alexander I. Alexandrov et al.   STRUCTURE