Harmine inhibits breast cancer cell migration and invasion by inducing the degradation of Twist1
Published 2021 View Full Article
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Title
Harmine inhibits breast cancer cell migration and invasion by inducing the degradation of Twist1
Authors
Keywords
Breast cancer, Metastasis, Cancers and neoplasms, Small interfering RNA, Messenger RNA, Vimentin, Wound healing, Cell wound assay
Journal
PLoS One
Volume 16, Issue 2, Pages e0247652
Publisher
Public Library of Science (PLoS)
Online
2021-02-25
DOI
10.1371/journal.pone.0247652
References
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Related references
Note: Only part of the references are listed.- Protein kinase Cα–mediated phosphorylation of Twist1 at Ser-144 prevents Twist1 ubiquitination and stabilizes it
- (2019) Roslyn Tedja et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- A First-in-Class TWIST1 Inhibitor with Activity in Oncogene-Driven Lung Cancer
- (2017) Zachary A. Yochum et al. MOLECULAR CANCER RESEARCH
- Roles and regulations of Hippo signaling during preimplantation mouse development
- (2016) Hiroshi Sasaki DEVELOPMENT GROWTH & DIFFERENTIATION
- An evolutionarily conserved DNA architecture determines target specificity of the TWIST family bHLH transcription factors
- (2015) Andrew T. Chang et al. GENES & DEVELOPMENT
- Targeting the Twist and Wnt signaling pathways in metastatic breast cancer
- (2014) Carlotta A. Glackin MATURITAS
- Silencing of Twist Expression by RNA Interference Suppresses Epithelial-mesenchymal Transition, Invasion, and Metastasis of Ovarian Cancer
- (2013) Wen-Shuang Wang et al. Asian Pacific Journal of Cancer Prevention
- TWIST1 associates with NF-κB subunit RELA via carboxyl-terminal WR domain to promote cell autonomous invasion through IL8 production
- (2012) Shan Li et al. BMC BIOLOGY
- A “Twist box” Code of p53 Inactivation: Twist box:p53 Interaction Promotes p53 Degradation
- (2012) Sara Piccinin et al. CANCER CELL
- Building prognostic models for breast cancer patients using clinical variables and hundreds of gene expression signatures
- (2011) Cheng Fan et al. BMC Medical Genomics
- Co-expression of SNAIL and TWIST determines prognosis in estrogen receptor–positive early breast cancer patients
- (2011) Johanna G. H. van Nes et al. BREAST CANCER RESEARCH AND TREATMENT
- Signaling mechanism of cell adhesion molecules in breast cancer metastasis: potential therapeutic targets
- (2011) Dong-Mei Li et al. BREAST CANCER RESEARCH AND TREATMENT
- Global cancer statistics
- (2011) Ahmedin Jemal et al. CA-A CANCER JOURNAL FOR CLINICIANS
- Normal and disease-related biological functions of Twist1 and underlying molecular mechanisms
- (2011) Qian Qin et al. CELL RESEARCH
- AACR Centennial Series: The Biology of Cancer Metastasis: Historical Perspective
- (2010) J. E. Talmadge et al. CANCER RESEARCH
- Epithelial-to-Mesenchymal Transitions and Circulating Tumor Cells
- (2010) Arnaud Bonnomet et al. JOURNAL OF MAMMARY GLAND BIOLOGY AND NEOPLASIA
- Mechanisms of Motility in Metastasizing Cells
- (2010) Mahmut Yilmaz et al. MOLECULAR CANCER RESEARCH
- Redundant or separate entities?--roles of Twist1 and Twist2 as molecular switches during gene transcription
- (2010) H. L. Franco et al. NUCLEIC ACIDS RESEARCH
- The beta-carboline alkaloid harmine inhibits BCRP and can reverse resistance to the anticancer drugs mitoxantrone and camptothecin in breast cancer cells
- (2009) Yonggang Ma et al. PHYTOTHERAPY RESEARCH
- Induction of EMT by Twist Proteins as a Collateral Effect of Tumor-Promoting Inactivation of Premature Senescence
- (2008) Stéphane Ansieau et al. CANCER CELL
- A Role for TAZ in Migration, Invasion, and Tumorigenesis of Breast Cancer Cells
- (2008) S. W. Chan et al. CANCER RESEARCH
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