Arylnaphthalene lactones: structures and pharmacological potentials

Update on naturally occurring novel arylnaphthalenes from plants

(2020) Shoujie Li et al.   PHYTOCHEMISTRY REVIEWS

Transition Metal-Mediated Annulation Approaches for Synthesis of Arylnaphthalene Lignan Lactones

(2020) Sooyoung Park et al.   Frontiers in Chemistry

Daurinol Attenuates Autoimmune Arthritis via Stabilization of Nrp1–PTEN–Foxp3 Signaling in Regulatory T Cells

(2019) Min-Jung Park et al.   Frontiers in Immunology

Anti-Inflammatory and Antinociceptive Studies of Hydroalcoholic Extract from the Leaves of Phyllanthus brasiliensis (Aubl.) Poir. and Isolation of 5-O-β-d-Glucopyranosyljusticidin B and Six Other Lignans

(2018) Luziane Borges et al.   MOLECULES

6′-Hydroxy Justicidin B Triggers a Critical Imbalance in Ca2+ Homeostasis and Mitochondrion-Dependent Cell Death in Human Leukemia K562 Cells

(2018) Jiaoyang Luo et al.   Frontiers in Pharmacology

New Anti-Inflammatory Aporphine and Lignan Derivatives from the Root Wood of Hernandia nymphaeifolia

(2018) Chuan-Yen Wei et al.   MOLECULES

Anti-HIV diphyllin glycosides from Justicia gendarussa

(2017) Hong-Jie Zhang et al.   PHYTOCHEMISTRY

Daurinol blocks breast and lung cancer metastasis and development by inhibition of focal adhesion kinase (FAK)

(2017) Jong Kyu Woo et al.   Oncotarget

New lignan glycosides from Justicia procumbens

(2016) Hong Jin et al.   JOURNAL OF ASIAN NATURAL PRODUCTS RESEARCH

Justicidin B: A Promising Bioactive Lignan

(2016) Shiva Hemmati et al.   MOLECULES

Recent advances in research on lignans and neolignans

(2016) Rémy Bertrand Teponno et al.   NATURAL PRODUCT REPORTS

The Neuroprotective Effects of Justicidin A on Amyloid Beta25–35-Induced Neuronal Cell Death Through Inhibition of Tau Hyperphosphorylation and Induction of Autophagy in SH-SY5Y Cells

(2016) Ming-Yao Gu et al.   NEUROCHEMICAL RESEARCH

Synthesis and anticancer activity of 4-aza-daurinol derivatives

(2015) Faisal Hayat et al.   ARCHIVES OF PHARMACAL RESEARCH

A Combined Transition-Metal-Catalyzed and Photopromoted Process: Synthesis of 2,3-Fused 4-Phenylnaphthalen-1-yl Carboxylates from 1,7-Diaryl-1,6-diynes

(2015) Yoshihiko Yamamoto et al.   CHEMISTRY-A EUROPEAN JOURNAL

Antiproliferative Compounds from Cleistanthus boivinianus from the Madagascar Dry Forest1

(2015) Yixi Liu et al.   JOURNAL OF NATURAL PRODUCTS

New cytotoxic lignan glycosides fromPhyllanthus glaucus

(2015) Shan Yu et al.   NATURAL PRODUCT RESEARCH

Synthesis of arylnaphthalene lignan lactone using benzoin condensation, intramolecular thermal cyclization and Suzuki coupling

(2015) Faisal Hayat et al.   TETRAHEDRON

A Novel Topoisomerase Inhibitor, Daurinol, Suppresses Growth of HCT116 Cells with Low Hematological Toxicity Compared to Etoposide

(2015) Kyungsu Kang et al.   NEOPLASIA

Synthesis and identification of cytotoxic diphyllin glycosides as vacuolar H+-ATPase inhibitors

(2014) Zhitao Zhang et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Cytotoxic activity of lignans from Justicia procumbens

(2014) Hong Jin et al.   FITOTERAPIA

Potent Cytotoxic Arylnaphthalene Lignan Lactones from Phyllanthus poilanei

(2014) Yulin Ren et al.   JOURNAL OF NATURAL PRODUCTS

Evaluation and Structure-Activity Relationship Analysis of a New Series of Arylnaphthalene lignans as Potential Anti-Tumor Agents

(2014) Jiaoyang Luo et al.   PLoS One

Anti-inflammatory and anti-osteoporotic lignans from Vitex negundo seeds

(2013) Cheng-Jian Zheng et al.   FITOTERAPIA

Regioselective route for arylnaphthalene lactones: convenient synthesis of taiwanin C, justicidin E, and daurinol

(2013) Ju-Eun Park et al.   TETRAHEDRON LETTERS

Arylnaphthalene lignan glycosides and other constituents fromPhyllanthus reticulatus

(2012) Jian-Xiong Ma et al.   JOURNAL OF ASIAN NATURAL PRODUCTS RESEARCH

JR6, a new compound isolated from Justicia procumbens, induces apoptosis in human bladder cancer EJ cells through caspase-dependent pathway

(2012) Xiao-Li He et al.   JOURNAL OF ETHNOPHARMACOLOGY

Effects of diphyllin as a novel V-ATPase inhibitor on gastric adenocarcinoma

(2011) Weidong Shen et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

New phenolic compounds fromLiatris elegans

(2010) Zhizhen Zhang et al.   NATURAL PRODUCT RESEARCH

Synthesis and bioevaluation of novel analogues of justicidin A

(2009) Zhao Yu et al.   MEDICINAL CHEMISTRY RESEARCH

Glycosides of arylnaphthalene lignans from Acanthus mollis having axial chirality

(2009) Tomáš Řezanka et al.   PHYTOCHEMISTRY

Three New Arylnaphthalide Lignans from the Aerial Parts ofBupleurum marginatumWall. ex DC.

(2008) Ying Liu et al.   HELVETICA CHIMICA ACTA

Three new lignan glycosides fromMananthes patentiflora

(2008) Jun-Mian Tian et al.   JOURNAL OF ASIAN NATURAL PRODUCTS RESEARCH

Dichapetalin-Type Triterpenoids and Lignans from the Aerial Parts ofPhyllanthus acutissima

(2008) Patoomratana Tuchinda et al.   JOURNAL OF NATURAL PRODUCTS

Complete assignments of1H and13C NMR data for three new arylnaphthalene lignan fromJusticia procumbens

(2008) Guorui Liu et al.   MAGNETIC RESONANCE IN CHEMISTRY