H2A.Z overexpression suppresses senescence and chemosensitivity in pancreatic ductal adenocarcinoma

Integrated analysis of H2A.Z isoforms function reveals a complex interplay in gene regulation

(2020) Assala Lamaa et al.   eLife

Hallmarks of Cellular Senescence

(2018) Alejandra Hernandez-Segura et al.   TRENDS IN CELL BIOLOGY

Distinct epigenetic landscapes underlie the pathobiology of pancreatic cancer subtypes

(2018) Gwen Lomberk et al.   Nature Communications

Variants of core histones and their roles in cell fate decisions, development and cancer

(2017) Marcus Buschbeck et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Acetylated histone variant H2A.Z is involved in the activation of neo-enhancers in prostate cancer

(2017) Fátima Valdés-Mora et al.   Nature Communications

Control of Gene Expression in Senescence through Transcriptional Read-Through of Convergent Protein-Coding Genes

(2017) Lisa Muniz et al.   Cell Reports

Histone variants on the move: substrates for chromatin dynamics

(2016) Paul B. Talbert et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Oncogenic potential of histone-variant H2A.Z.1 and its regulatory role in cell cycle and epithelial-mesenchymal transition in liver cancer

(2016) Hee Doo Yang et al.   Oncotarget

H2A.Z.1 Monoubiquitylation Antagonizes BRD2 to Maintain Poised Chromatin in ESCs

(2016) Lauren E. Surface et al.   Cell Reports

Pancreatic cancer

(2016) Jorg Kleeff et al.   Nature Reviews Disease Primers

Senescence from G2 arrest, revisited

(2015) Véronique Gire et al.   CELL CYCLE

Histone Variant H2A.Z.2 Mediates Proliferation and Drug Sensitivity of Malignant Melanoma

(2015) Chiara Vardabasso et al.   MOLECULAR CELL

Circulating nucleosomes as epigenetic biomarkers in pancreatic cancer

(2015) Monika Bauden et al.   Clinical Epigenetics

Projecting Cancer Incidence and Deaths to 2030: The Unexpected Burden of Thyroid, Liver, and Pancreas Cancers in the United States

(2014) L. Rahib et al.   CANCER RESEARCH

Every amino acid matters: essential contributions of histone variants to mammalian development and disease

(2014) Ian Maze et al.   NATURE REVIEWS GENETICS

Epigenetics and pancreatic cancer: Pathophysiology and novel treatment aspects

(2014) Daniel Neureiter   WORLD JOURNAL OF GASTROENTEROLOGY

Histone variants: emerging players in cancer biology

(2013) Chiara Vardabasso et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Histone variants in pluripotency and disease

(2013) P. J. Skene et al.   DEVELOPMENT

Gene dysregulation by histone variant H2A.Z in bladder cancer

(2013) Kyunghwan Kim et al.   Epigenetics & Chromatin

H2A.Z Facilitates Access of Active and Repressive Complexes to Chromatin in Embryonic Stem Cell Self-Renewal and Differentiation

(2012) Gangqing Hu et al.   Cell Stem Cell

H2A.Z.2.2 is an alternatively spliced histone H2A.Z variant that causes severe nucleosome destabilization

(2012) Clemens Bönisch et al.   NUCLEIC ACIDS RESEARCH

p53 and p16INK4A independent induction of senescence by chromatin-dependent alteration of S-phase progression

(2011) Alexandre Prieur et al.   Nature Communications

A decrease in cyclin B1 levels leads to polyploidization in DNA damage-induced senescence

(2010) Ikue Kikuchi et al.   CELL BIOLOGY INTERNATIONAL

H2A.Z overexpression promotes cellular proliferation of breast cancer cells

(2010) Amy Svotelis et al.   CELL CYCLE

The essence of senescence

(2010) T. Kuilman et al.   GENES & DEVELOPMENT

The E1A-Associated p400 Protein Modulates Cell Fate Decisions by the Regulation of ROS Homeostasis

(2010) Lise Mattera et al.   PLoS Genetics

Characterization of the histone H2A.Z-1 and H2A.Z-2 isoforms in vertebrates

(2009) Deanna Dryhurst et al.   BMC BIOLOGY

Epigenetics in cancer

(2009) S. Sharma et al.   CARCINOGENESIS

Regulation of fatty acid synthesis and Δ9-desaturation in senescence of human fibroblasts

(2008) Miho Maeda et al.   LIFE SCIENCES