Characterisation of MS phenotypes across the age span using a novel data set integrating 34 clinical trials (NO.MS cohort): Age is a key contributor to presentation

The influence of age at disease onset on future relapses and disability progression in multiple sclerosis patients on immunomodulatory treatment

(2020) Viktor von Wyl et al.   EUROPEAN JOURNAL OF NEUROLOGY

Timing of high-efficacy therapy for multiple sclerosis: a retrospective observational cohort study

(2020) Anna He et al.   LANCET NEUROLOGY

Systematic review of prediction models in relapsing remitting multiple sclerosis

(2020) Fraser S. Brown et al.   PLoS One

Contribution of Relapse-Independent Progression vs Relapse-Associated Worsening to Overall Confirmed Disability Accumulation in Typical Relapsing Multiple Sclerosis in a Pooled Analysis of 2 Randomized Clinical Trials

(2020) Ludwig Kappos et al.   JAMA Neurology

Long-term disability progression ofpediatric-onset multiple sclerosis

(2019) Kyla A. McKay et al.   NEUROLOGY

Current therapeutic landscape in multiple sclerosis

(2019) Bruce A.C. Cree et al.   CURRENT OPINION IN NEUROLOGY

Leveraging real-world data to investigate multiple sclerosis disease behavior, prognosis, and treatment

(2019) Jeffrey A Cohen et al.   Multiple Sclerosis Journal

Beyond Randomized Clinical Trials: Use of External Controls

(2019) Heinz Schmidli et al.   CLINICAL PHARMACOLOGY & THERAPEUTICS

The influence and impact of ageing and immunosenescence (ISC) on adaptive immunity during multiple sclerosis (MS) and the animal counterpart experimental autoimmune encephalomyelitis (EAE)

(2018) Christopher Bolton et al.   AGEING RESEARCH REVIEWS

Siponimod versus placebo in secondary progressive multiple sclerosis (EXPAND): a double-blind, randomised, phase 3 study

(2018) Ludwig Kappos et al.   LANCET

The MSOAC approach to developing performance outcomes to measure and monitor multiple sclerosis disability

(2017) Nicholas G LaRocca et al.   Multiple Sclerosis Journal

Treatment decisions in multiple sclerosis — insights from real-world observational studies

(2017) Maria Trojano et al.   Nature Reviews Neurology

The MSOAC approach to developing performance outcomes to measure and monitor multiple sclerosis disability

(2017) Nicholas G LaRocca et al.   Multiple Sclerosis Journal

Meta-analysis of the Age-Dependent Efficacy of Multiple Sclerosis Treatments

(2017) Ann Marie Weideman et al.   Frontiers in Neurology

Exploration of machine learning techniques in predicting multiple sclerosis disease course

(2017) Yijun Zhao et al.   PLoS One

Defining brain volume cutoffs to identify clinically relevant atrophy in RRMS

(2016) Maria Pia Sormani et al.   Multiple Sclerosis Journal

Data quality evaluation for observational multiple sclerosis registries

(2016) Tomas Kalincik et al.   Multiple Sclerosis Journal

The relationship of age with the clinical phenotype in multiple sclerosis

(2016) A Scalfari et al.   Multiple Sclerosis Journal

Multimodal population brain imaging in the UK Biobank prospective epidemiological study

(2016) Karla L Miller et al.   NATURE NEUROSCIENCE

Defining brain volume cutoffs to identify clinically relevant atrophy in RRMS

(2016) Maria Pia Sormani et al.   Multiple Sclerosis Journal

Data quality evaluation for observational multiple sclerosis registries

(2016) Tomas Kalincik et al.   Multiple Sclerosis Journal

The relationship of age with the clinical phenotype in multiple sclerosis

(2016) A Scalfari et al.   Multiple Sclerosis Journal

UK Biobank: An Open Access Resource for Identifying the Causes of a Wide Range of Complex Diseases of Middle and Old Age

(2015) Cathie Sudlow et al.   PLOS MEDICINE

Defining the clinical course of multiple sclerosis: The 2013 revisions

(2014) F. D. Lublin et al.   NEUROLOGY

Metabias: A Challenge for Comparative Effectiveness Research

(2013) Steven Goodman et al.   ANNALS OF INTERNAL MEDICINE

Elevated relapse rates in pediatric compared to adult MS persist for at least 6 years

(2013) L.A. Benson et al.   Multiple Sclerosis and Related Disorders

Early Relapses, Onset of Progression, and Late Outcome in Multiple Sclerosis

(2012) Antonio Scalfari et al.   JAMA Neurology

Assessing brain atrophy rates in a large population of untreated multiple sclerosis subtypes

(2010) N. De Stefano et al.   NEUROLOGY

Functional and Structural Connectivity of the Motor Network in Pediatric and Adult-Onset Relapsing-Remitting Multiple Sclerosis

(2010) Maria A. Rocca et al.   RADIOLOGY

Relapses in multiple sclerosis are age- and time-dependent

(2008) H Tremlett et al.   JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY