Oral Coadministration of Zn-Insulin with d-Form Small Intestine-Permeable Cyclic Peptide Enhances Its Blood Glucose-Lowering Effect in Mice

Zwitterionic micelles efficiently deliver oral insulin without opening tight junctions

(2020) Xiangfei Han et al.   Nature Nanotechnology

Molecular engineering of safe and efficacious oral basal insulin

(2020) Frantisek Hubálek et al.   Nature Communications

Efficacy and safety of oral basal insulin versus subcutaneous insulin glargine in type 2 diabetes: a randomised, double-blind, phase 2 trial

(2019) Inge B Halberg et al.   Lancet Diabetes & Endocrinology

Oral insulin therapy for primary prevention of type 1 diabetes in infants with high genetic risk: the GPPAD-POInT (global platform for the prevention of autoimmune diabetes primary oral insulin trial) study protocol

(2019) Anette-Gabriele Ziegler et al.   BMJ Open

Silica-Coated Nanoparticles with a Core of Zinc, l-Arginine, and a Peptide Designed for Oral Delivery

(2019) Delyan Hristov et al.   ACS Applied Materials & Interfaces

Effect of Oral Insulin on Prevention of Diabetes in Relatives of Patients With Type 1 Diabetes

(2017) et al.   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

Identification of cyclic peptides for facilitation of transcellular transport of phages across intestinal epithelium in vitro and in vivo

(2017) Shunsuke Yamaguchi et al.   JOURNAL OF CONTROLLED RELEASE

Current status of selected oral peptide technologies in advanced preclinical development and in clinical trials

(2016) T.A.S. Aguirre et al.   ADVANCED DRUG DELIVERY REVIEWS

Self-assembled lecithin/chitosan nanoparticles for oral insulin delivery: preparation and functional evaluation

(2016) Yuling Liu et al.   International Journal of Nanomedicine

An l- to d-Amino Acid Conversion in an Endosomolytic Analog of the Cell-penetrating Peptide TAT Influences Proteolytic Stability, Endocytic Uptake, and Endosomal Escape

(2016) Kristina Najjar et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

In vivo proof of concept of oral insulin delivery based on a co-administration strategy with the cell-penetrating peptide penetratin

(2014) Ebbe Juel Bech Nielsen et al.   JOURNAL OF CONTROLLED RELEASE

Nonmetabolic Complications of Continuous Subcutaneous Insulin Infusion: A Patient Survey

(2013) John C. Pickup et al.   Diabetes Technology & Therapeutics

Mechanistic Study of the Uptake/Permeation of Cell-Penetrating Peptides Across a Caco-2 Monolayer and Their Stimulatory Effect on Epithelial Insulin Transport

(2013) Noriyasu Kamei et al.   JOURNAL OF PHARMACEUTICAL SCIENCES

Biodegradable, pH-Responsive Carboxymethyl Cellulose/Poly(Acrylic Acid) Hydrogels for Oral Insulin Delivery

(2013) Xiaoye Gao et al.   MACROMOLECULAR BIOSCIENCE

Preferential Uptake of L- versus D-Amino Acid Cell-Penetrating Peptides in a Cell Type-Dependent Manner

(2011) Wouter P.R. Verdurmen et al.   CHEMISTRY & BIOLOGY

Enteric-coated capsules filled with freeze-dried chitosan/poly(γ-glutamic acid) nanoparticles for oral insulin delivery

(2010) Kiran Sonaje et al.   BIOMATERIALS

Results and analysis of the 2008-2009 Insulin Injection Technique Questionnaire survey

(2010) Carina DE CONINCK et al.   Journal of Diabetes

Usefulness of cell-penetrating peptides to improve intestinal insulin absorption

(2008) Noriyasu Kamei et al.   JOURNAL OF CONTROLLED RELEASE