The metaeffector MesI regulates the activity of the Legionella effector SidI through direct protein-protein interactions

The Legionella pneumophila metaeffector Lpg2505 (MesI) regulates SidI-mediated translation inhibition and novel glycosyl hydrolase activity

(2020) Ashley M. Joseph et al.   INFECTION AND IMMUNITY

Structural insights into the mechanism and inhibition of transglutaminase-induced ubiquitination by the Legionella effector MavC

(2020) Yajuan Mu et al.   Nature Communications

Legionella pneumophila translocated translation inhibitors are required for bacterial-induced host cell cycle arrest

(2019) Asaf Sol et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

A Legionella pneumophila Kinase Phosphorylates the Hsp70 Chaperone Family to Inhibit Eukaryotic Protein Synthesis

(2019) Steven M. Moss et al.   Cell Host & Microbe

Bacterial pseudokinase catalyzes protein polyglutamylation to inhibit the SidE-family ubiquitin ligases

(2019) Miles H. Black et al.   SCIENCE

Regulation of phosphoribosyl ubiquitination by a calmodulin-dependent glutamylase

(2019) Ninghai Gan et al.   NATURE

Inhibition of bacterial ubiquitin ligases by SidJ–calmodulin-catalysed glutamylation

(2019) Sagar Bhogaraju et al.   NATURE

Protein polyglutamylation catalyzed by the bacterial calmodulin-dependent pseudokinase SidJ

(2019) Alan Sulpizio et al.   eLife

Legionella pneumophila regulates the activity of UBE 2N by deamidase‐mediated deubiquitination

(2019) Ninghai Gan et al.   EMBO JOURNAL

Discovery of Ubiquitin Deamidases in the Pathogenic Arsenal of Legionella pneumophila

(2018) Dylan Valleau et al.   Cell Reports

Legionella and Coxiella effectors: strength in diversity and activity

(2017) Jiazhang Qiu et al.   NATURE REVIEWS MICROBIOLOGY

MultipleLegionella pneumophilaeffector virulence phenotypes revealed through high-throughput analysis of targeted mutant libraries

(2017) Stephanie R. Shames et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Positive and Negative Regulation of the Master Metabolic Regulator mTORC1 by Two Families of Legionella pneumophila Effectors

(2017) Justin A. De Leon et al.   Cell Reports

Diverse mechanisms of metaeffector activity in an intracellular bacterial pathogen, Legionella pneumophila

(2016) Malene L Urbanus et al.   Molecular Systems Biology

Genomic analysis of 38 Legionella species identifies large and diverse effector repertoires

(2016) David Burstein et al.   NATURE GENETICS

The Machinery at Endoplasmic Reticulum-Plasma Membrane Contact Sites Contributes to Spatial Regulation of Multiple Legionella Effector Proteins

(2014) Andree Hubber et al.   PLoS Pathogens

Poison Domains Block Transit of Translocated Substrates via the Legionella pneumophila Icm/Dot System

(2013) Whitney M. Amyot et al.   INFECTION AND IMMUNITY

IL-1  Signaling Initiates the Inflammatory Response to Virulent Legionella pneumophila In Vivo

(2013) K. C. Barry et al.   JOURNAL OF IMMUNOLOGY

The bacterial two-hybrid system based on adenylate cyclase reconstitution in Escherichia coli

(2012) Aurélia Battesti et al.   METHODS

Legionella pneumophila SidD is a deAMPylase that modifies Rab1

(2011) Yunhao Tan et al.   NATURE

Legionella pneumophila regulates the small GTPase Rab1 activity by reversible phosphorylcholination

(2011) Y. Tan et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

De-AMPylation of the Small GTPase Rab1 by the Pathogen Legionella pneumophila

(2011) M. R. Neunuebel et al.   SCIENCE

Secreted Bacterial Effectors That Inhibit Host Protein Synthesis Are Critical for Induction of the Innate Immune Response to Virulent Legionella pneumophila

(2011) Mary F. Fontana et al.   PLoS Pathogens

Inhibition of Host Vacuolar H+-ATPase Activity by a Legionella pneumophila Effector

(2010) Li Xu et al.   PLoS Pathogens

Legionella Metaeffector Exploits Host Proteasome to Temporally Regulate Cognate Effector

(2010) Tomoko Kubori et al.   PLoS Pathogens

Targeting eEF1A by aLegionella pneumophilaeffector leads to inhibition of protein synthesis and induction of host stress response

(2009) Xihui Shen et al.   CELLULAR MICROBIOLOGY

Lgt: a Family of Cytotoxic Glucosyltransferases Produced by Legionella pneumophila

(2008) Y. Belyi et al.   JOURNAL OF BACTERIOLOGY

The Legionella pneumophila replication vacuole: making a cosy niche inside host cells

(2008) Ralph R. Isberg et al.   NATURE REVIEWS MICROBIOLOGY