Ligustrazine alleviates cyclophosphamide-induced hepatotoxicity via the inhibition of Txnip/Trx/NF-κB pathway

The protective effects of pretreatment with resveratrol in cyclophosphamide-induced rat ovarian granulosa cell injury: In vitro study

(2020) Zhaoyan Nie et al.   REPRODUCTIVE TOXICOLOGY

Nerolidol protects the liver against cyclophosphamide‐induced hepatic inflammation, apoptosis, and fibrosis via modulation of Nrf2, NF‐κB p65, and caspase‐3 signaling molecules in Swiss albino mice

(2020) Ashif Iqubal et al.   BIOFACTORS

Study on the attenuated effect of Ginkgolide B on ferroptosis in high fat diet induced nonalcoholic fatty liver disease

(2020) Yuwei Yang et al.   TOXICOLOGY

Resveratrol Suppresses Aβ-Induced Microglial Activation Through the TXNIP/TRX/NLRP3 Signaling Pathway

(2019) Lifang Feng et al.   DNA AND CELL BIOLOGY

Severe and prolonged cyclophosphamide-induced hepatotoxicity in a breast cancer patient carrying a CYP2B6*7 variant

(2019) Zhao Ming et al.   PHARMACOGENOMICS

Role of aldosterone in the activation of primary mice hepatic stellate cell and liver fibrosis via NLRP3 inflammasome

(2019) Yang Li et al.   JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY

NEK7 interacts with NLRP3 to modulate the pyroptosis in inflammatory bowel disease via NF-κB signaling

(2019) Xueliang Chen et al.   Cell Death & Disease

Nrf2 inhibits NLRP3 inflammasome activation through regulating Trx1/TXNIP complex in cerebral ischemia reperfusion injury

(2018) Yanghao Hou et al.   BEHAVIOURAL BRAIN RESEARCH

Silymarin attenuated paraquat-induced cytotoxicity in macrophage by regulating Trx/TXNIP complex, inhibiting NLRP3 inflammasome activation and apoptosis

(2018) Zhenning Liu et al.   TOXICOLOGY IN VITRO

Ligand Activation of PPARγ by Ligustrazine Suppresses Pericyte Functions of Hepatic Stellate Cells via SMRT-Mediated Transrepression of HIF-1α

(2018) Feng Zhang et al.   Theranostics

Ligustrazine attenuates inflammation and oxidative stress in a rat model of arthritis via the Sirt1/NF-κB and Nrf-2/HO-1 pathways

(2018) Yongji Li et al.   ARCHIVES OF PHARMACAL RESEARCH

Ganoderic acid A against cyclophosphamide-induced hepatic toxicity in mice

(2018) Xu Lixin et al.   JOURNAL OF BIOCHEMICAL AND MOLECULAR TOXICOLOGY

Ligustrazine attenuates inflammation and the associated chemokines and receptors in ovalbumine-induced mouse asthma model

(2016) Ying Wei et al.   ENVIRONMENTAL TOXICOLOGY AND PHARMACOLOGY

Punicalagin alleviates hepatotoxicity in rats challenged with cyclophosphamide

(2016) Amr A. Fouad et al.   ENVIRONMENTAL TOXICOLOGY AND PHARMACOLOGY

Nrf2 Activation Is Required for Ligustrazine to Inhibit Hepatic Steatosis in Alcohol-Preferring Mice and Hepatocytes

(2016) Chunfeng Lu et al.   TOXICOLOGICAL SCIENCES

Nrf2 knockdown attenuates the ameliorative effects of ligustrazine on hepatic fibrosis by targeting hepatic stellate cell transdifferentiation

(2016) Chunfeng Lu et al.   TOXICOLOGY

Protective effects of Nigella sativa oil and thymoquinone against toxicity induced by the anticancer drug cyclophosphamide

(2016) F. Q. Alenzi et al.   BRITISH JOURNAL OF BIOMEDICAL SCIENCE

Ligustrazine prevents alcohol-induced liver injury by attenuating hepatic steatosis and oxidative stress

(2015) Chunfeng Lu et al.   INTERNATIONAL IMMUNOPHARMACOLOGY

Tetramethylpyrazine reduces inflammation in liver fibrosis and inhibits inflammatory cytokine expression in hepatic stellate cells by modulating NLRP3 inflammasome pathway

(2015) Xiafei Wu et al.   IUBMB LIFE

Cleavage of GSDMD by inflammatory caspases determines pyroptotic cell death

(2015) Jianjin Shi et al.   NATURE

NLRP3 inflammasome: From a danger signal sensor to a regulatory node of oxidative stress and inflammatory diseases

(2015) Amna Abderrazak et al.   Redox Biology

Apoptosis-Associated Speck-like Protein Containing a CARD Forms Specks but Does Not Activate Caspase-1 in the Absence of NLRP3 during Macrophage Swelling

(2015) Vincent Compan et al.   JOURNAL OF IMMUNOLOGY

Hyperglycemia Regulates TXNIP/TRX/ROS Axis via p38 MAPK and ERK Pathways in Pancreatic Cancer

(2014) Wei Li et al.   CURRENT CANCER DRUG TARGETS

Ameliorative effect of propolis against cyclophosphamide-induced toxicity in mice

(2014) Sabry A. El-Naggar et al.   PHARMACEUTICAL BIOLOGY

Peroxisome Proliferator Activator Receptor (PPAR)-γLigand, but Not PPAR-α, Ameliorates Cyclophosphamide-Induced Oxidative Stress and Inflammation in Rat Liver

(2014) Azza A. K. El-Sheikh et al.   PPAR Research

Thioredoxin/Txnip: Redoxisome, as a Redox Switch for the Pathogenesis of Diseases

(2014) Eiji Yoshihara et al.   Frontiers in Immunology

Thioredoxin-mediated Denitrosylation Regulates Cytokine-induced Nuclear Factor κB (NF-κB) Activation

(2013) Zachary T. Kelleher et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Cyclophosphamide-induced nephrotoxicity, genotoxicity, and damage in kidney genomic DNA of Swiss albino mice: the protective effect of Ellagic acid

(2012) Muneeb U. Rehman et al.   MOLECULAR AND CELLULAR BIOCHEMISTRY

Carbon Nanotube Based DNA Biosensor for Rapid Detection of Anti-Cancer Drug of Cyclophosphamide

(2009) Sigen Wang et al.   Current Nanoscience

Antioxidative effect of the herbal remedy Qin Huo Yi Hao and its active component tetramethylpyrazine on high glucose-treated endothelial cells

(2009) Yingxiu Kang et al.   LIFE SCIENCES

Antioxidation and anti-inflammation by haem oxygenase-1 contribute to protection by tetramethylpyrazine against gentamicin-induced apoptosis in murine renal tubular cells

(2008) Y.-M. Sue et al.   NEPHROLOGY DIALYSIS TRANSPLANTATION