Machine learning and accelerated stress approaches to differentiate potential causes of aggregation in polyclonal antibody formulations during shipping
Published 2021 View Full Article
- Home
- Publications
- Publication Search
- Publication Details
Title
Machine learning and accelerated stress approaches to differentiate potential causes of aggregation in polyclonal antibody formulations during shipping
Authors
Keywords
Protein aggregation, Machine learning, Protein formulation, Antibodies
Journal
JOURNAL OF PHARMACEUTICAL SCIENCES
Volume -, Issue -, Pages -
Publisher
Elsevier BV
Online
2021-02-27
DOI
10.1016/j.xphs.2021.02.029
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- Aggregation and Particle Formation During Pumping of an Antibody Formulation Are Controlled by Electrostatic Interactions Between Pump Surfaces and Protein Molecules
- (2020) Hao Wu et al. JOURNAL OF PHARMACEUTICAL SCIENCES
- The Effect of Container Surface Passivation on Aggregation of Intravenous Immunoglobulin Induced by Mechanical Shock
- (2020) Sanli Movafaghi et al. Biotechnology Journal
- A Review on Mixing-Induced Protein Particle Formation: The Puzzle of Bottom-Mounted Mixers
- (2020) Benson Gikanga et al. JOURNAL OF PHARMACEUTICAL SCIENCES
- Machine learning and statistical analyses for extracting and characterizing “fingerprints” of antibody aggregation at container interfaces from flow microscopy images
- (2020) Austin L. Daniels et al. BIOTECHNOLOGY AND BIOENGINEERING
- DEHP Nanodroplets Leached From Polyvinyl Chloride IV Bags Promote Aggregation of IVIG and Activate Complement in Human Serum
- (2019) Jared R. Snell et al. JOURNAL OF PHARMACEUTICAL SCIENCES
- Container Surfaces Control Initiation of Cavitation and Resulting Particle Formation in Protein Formulations After Application of Mechanical Shock
- (2019) Hao Wu et al. JOURNAL OF PHARMACEUTICAL SCIENCES
- Mechanical Shock During Shipping of Medications: The Roles of Packaging and Transportation Vendors
- (2019) Sarah Dill et al. JOURNAL OF PHARMACEUTICAL SCIENCES
- Automatic Identification of the Stress Sources of Protein Aggregates Using Flow Imaging Microscopy Images
- (2019) Arni Gambe-Gilbuena et al. JOURNAL OF PHARMACEUTICAL SCIENCES
- Subvisible Particles in IVIg Formulations Activate Complement in Human Serum
- (2019) Carly F. Chisholm et al. JOURNAL OF PHARMACEUTICAL SCIENCES
- Shocking Data On Parcel Shipments of Protein Solutions
- (2019) Christine Siska et al. JOURNAL OF PHARMACEUTICAL SCIENCES
- Impact of Cavitation, High Shear Stress and Air/Liquid Interfaces on Protein Aggregation
- (2018) Mark Duerkop et al. Biotechnology Journal
- Postproduction Handling and Administration of Protein Pharmaceuticals and Potential Instability Issues
- (2018) M. Reza Nejadnik et al. JOURNAL OF PHARMACEUTICAL SCIENCES
- Deep Convolutional Neural Network Analysis of Flow Imaging Microscopy Data to Classify Subvisible Particles in Protein Formulations
- (2018) Christopher P. Calderon et al. JOURNAL OF PHARMACEUTICAL SCIENCES
- Impact of Cavitation, High Shear Stress and Air/Liquid Interfaces on Protein Aggregation
- (2018) Mark Duerkop et al. Biotechnology Journal
- Protein aggregation – Mechanisms, detection, and control
- (2018) Wei Wang et al. INTERNATIONAL JOURNAL OF PHARMACEUTICS
- Rapid Quantification of Protein Particles in High-Concentration Antibody Formulations
- (2018) Hao Wu et al. JOURNAL OF PHARMACEUTICAL SCIENCES
- Synergistic Effect of Cavitation and Agitation on Protein Aggregation
- (2017) Tetsuo Torisu et al. JOURNAL OF PHARMACEUTICAL SCIENCES
- Mechanics of collapsing cavitation bubbles
- (2016) Leen van Wijngaarden ULTRASONICS SONOCHEMISTRY
- Nucleus factory on cavitation bubble for amyloid β fibril
- (2016) Kichitaro Nakajima et al. Scientific Reports
- Do Not Drop: Mechanical Shock in Vials Causes Cavitation, Protein Aggregation, and Particle Formation
- (2015) Theodore W. Randolph et al. JOURNAL OF PHARMACEUTICAL SCIENCES
- Introduction to current and future protein therapeutics: A protein engineering perspective
- (2011) Paul J. Carter EXPERIMENTAL CELL RESEARCH
- Classification and Characterization of Therapeutic Antibody Aggregates
- (2011) Marisa K. Joubert et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- An Industry Perspective on the Monitoring of Subvisible Particles as a Quality Attribute for Protein Therapeutics
- (2010) Satish K. Singh et al. JOURNAL OF PHARMACEUTICAL SCIENCES
- Delivery of Therapeutic Proteins
- (2010) Dipak S. Pisal et al. JOURNAL OF PHARMACEUTICAL SCIENCES
- Intravenous immunoglobulin: Adverse reactions and management
- (2008) Francisco A. Bonilla JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY
- Shaken, Not Stirred: Mechanical Stress Testing of an IgG1 Antibody
- (2008) Sylvia Kiese et al. JOURNAL OF PHARMACEUTICAL SCIENCES
Discover Peeref hubs
Discuss science. Find collaborators. Network.
Join a conversationPublish scientific posters with Peeref
Peeref publishes scientific posters from all research disciplines. Our Diamond Open Access policy means free access to content and no publication fees for authors.
Learn More