Randomized Clinical Trial or Real-World Evidence: How Historical Events, Public Demand, and the Resulting Laws and Regulations Shaped the Body of Medical Evidence

The Use of Real-World Evidence and Data in Clinical Research and Postapproval Safety Studies

(2018) Mary Jo Lamberti et al.   Therapeutic Innovation & Regulatory Science

Hawthorne effect reporting in orthodontic randomized controlled trials: truth or myth? Blessing or curse?

(2017) Salem Abdulraheem et al.   EUROPEAN JOURNAL OF ORTHODONTICS

Assessing the Gold Standard — Lessons from the History of RCTs

(2016) Laura E. Bothwell et al.   NEW ENGLAND JOURNAL OF MEDICINE

The history and fate of the gold standard

(2015) David S Jones et al.   LANCET

Reform, Regulation, and Pharmaceuticals — The Kefauver–Harris Amendments at 50

(2012) Jeremy A. Greene et al.   NEW ENGLAND JOURNAL OF MEDICINE

Ethical and Scientific Implications of the Globalization of Clinical Research

(2009) Seth W. Glickman et al.   NEW ENGLAND JOURNAL OF MEDICINE