4.7 Article

The prevalence and risk factors of depression in prenatal and postnatal women in China with the outbreak of Corona Virus Disease 2019

Journal

JOURNAL OF AFFECTIVE DISORDERS
Volume 282, Issue -, Pages 1203-1209

Publisher

ELSEVIER
DOI: 10.1016/j.jad.2021.01.019

Keywords

Maternal health; Depression; Anxiety; Insomnia; Corona Virus Disease 2019

Funding

  1. Sanming Project of Medicine in Shenzhen [SZSM202011014]
  2. Shenzhen Fund for Guangdong Provincial High-level Clinical Key Specialties [SZGSP013]

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The prevalence rate of depression among Chinese prenatal and postnatal women during the COVID-19 outbreak was 35.4%. Risk factors for depression included drinking, nausea and vomiting during pregnancy, pregnancy's influence on mobility, anxiety, insomnia, and inadequate daily monitoring of fetal movement.
Background: The prevalence of depression increase with the outbreaks of epidemic disease. The prevalence of depression during the outbreak of Corona Virus Disease 2019 (COVID-19) in prenatal and postnatal women was examined in China. Methods: 2201 prenatal and postnatal women in mainland China were recruited in this cross-sectional study from February 28th to April 26th, 2020. The Patient Health Questionnaire (PHQ-9) was used to assess depression in prenatal and postnatal women. Results: The prevalence rate of depression was 35.4%. The risk factors for depression included drinking (p = 0.04; adjusted OR = 2.81, 95%CI: 1.26 similar to 6.24), nausea and vomiting during pregnancy (p < 0.001; adjusted OR = 3.54, 95%CI: 1.10 similar to 11.44), pregnancy's influence on mobility (p = 0.02; adjusted OR = 1.42, 95%CI: 1.11 similar to 1.83), anxiety (p < 0.001; adjusted OR = 1.66, 95%CI: 1.57 similar to 1.75), insomnia (p < 0.001; adjusted OR = 1.17, 95%CI: 1.14 similar to 1.21) and daily attention to fetal movement (p < 0.001; adjusted OR = 0.41, 95%CI: 0.31 similar to 0.56). Limitations: This study used a cross-sectional design, and cannot compare changes in the incidence of depression before and after the COVID-19 outbreak. Conclusions: During the COVID-19 outbreak, the prevalence rate of depression among Chinese prenatal and postnatal women was 35.4%. Moreover, anxiety, insomnia, drinking, nausea and vomiting during pregnancy, as well as the impaired movement and less daily monitoring of fetal movement were risk factors for depression.

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