Strategies for cancer gene-delivery improvement by non-viral vectors

A Non-Viral Plasmid DNA Delivery System Consisting on a Lysine-Derived Cationic Lipid Mixed with a Fusogenic Lipid

(2019) María Martínez-Negro et al.   Pharmaceutics

A Gemini Cationic Lipid with Histidine Residues as a Novel Lipid-Based Gene Nanocarrier: A Biophysical and Biochemical Study

(2018) María Martínez-Negro et al.   Nanomaterials

Preclinical Mammalian Safety Studies of EPHARNA (DOPC Nanoliposomal EphA2-Targeted siRNA)

(2017) Michael J. Wagner et al.   MOLECULAR CANCER THERAPEUTICS

Hyaluronic acid-conjugated lipoplexes for targeted delivery of siRNA in a murine metastatic lung cancer model

(2016) Thais Leite Nascimento et al.   INTERNATIONAL JOURNAL OF PHARMACEUTICS

Preclinical Justification of pbi-shRNA EWS/FLI1 Lipoplex (LPX) Treatment for Ewing's Sarcoma

(2016) Donald D. Rao et al.   MOLECULAR THERAPY

A Phase l Study of a Tumor-targeted Systemic Nanodelivery System, SGT-94, in Genitourinary Cancers

(2016) Arlene Siefker-Radtke et al.   MOLECULAR THERAPY

Host-Guest-Mediated DNA Templation of Polycationic Supramolecules for Hierarchical Nanocondensation and the Delivery of Gene Material

(2015) Laura Gallego-Yerga et al.   CHEMISTRY-A EUROPEAN JOURNAL

Evaluation of improved PAMAM-G5 conjugates for gene delivery targeted to the transferrin receptor

(2015) Koldo Urbiola et al.   EUROPEAN JOURNAL OF PHARMACEUTICS AND BIOPHARMACEUTICS

Asialoglycoprotein receptor mediated hepatocyte targeting — Strategies and applications

(2015) Anisha A. D'Souza et al.   JOURNAL OF CONTROLLED RELEASE

A phase II trial of intraperitoneal EGEN-001, an IL-12 plasmid formulated with PEG–PEI–cholesterol lipopolymer in the treatment of persistent or recurrent epithelial ovarian, fallopian tube or primary peritoneal cancer: A Gynecologic Oncology Group study

(2014) Ronald D. Alvarez et al.   GYNECOLOGIC ONCOLOGY

Improving the systemic drug delivery efficacy of nanoparticles using a transferrin variant for targeting

(2014) Ricky Y.T. Chiu et al.   JOURNAL OF CONTROLLED RELEASE

Nanodelivery Systems for Nucleic Acid Therapeutics in Drug Resistant Tumors

(2014) Arun K. Iyer et al.   MOLECULAR PHARMACEUTICS

Efficient targeted gene delivery by a novel PAMAM/DNA dendriplex coated with hyaluronic acid

(2014) Koldo Urbiola et al.   Nanomedicine

Correlating animal and human phase Ia/Ib clinical data with CALAA-01, a targeted, polymer-based nanoparticle containing siRNA

(2014) J. E. Zuckerman et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Tumor Imaging and Interferon- -Inducible Protein-10 Gene Transfer Using a Highly Efficient Transferrin-Conjugated Liposome System in Mice

(2013) H. Zhuo et al.   CLINICAL CANCER RESEARCH

Targeted gene delivery by new folate–polycationic amphiphilic cyclodextrin–DNA nanocomplexes in vitro and in vivo

(2013) Cristina Aranda et al.   EUROPEAN JOURNAL OF PHARMACEUTICS AND BIOPHARMACEUTICS

First-in-Humans Trial of an RNA Interference Therapeutic Targeting VEGF and KSP in Cancer Patients with Liver Involvement

(2013) Josep Tabernero et al.   Cancer Discovery

Phase I clinical development of Atu027, a siRNA formulation targeting PKN3 in patients with advanced solid tumors

(2011) Dirk Strumberg et al.   INTERNATIONAL JOURNAL OF CLINICAL PHARMACOLOGY AND THERAPEUTICS

Factors Determining the Superior Performance of Lipid/DNA/Protammine Nanoparticles over Lipoplexes

(2011) Giulio Caracciolo et al.   JOURNAL OF MEDICINAL CHEMISTRY

Synthesis of Cationic Carbosilane Dendrimers via Click Chemistry and Their Use as Effective Carriers for DNA Transfection into Cancerous Cells

(2011) Eduardo Arnáiz et al.   MOLECULAR PHARMACEUTICS

Polycationic amphiphilic cyclodextrin-based nanoparticles for therapeutic gene delivery

(2011) Alejandro Méndez-Ardoy et al.   Nanomedicine

A phase 2 study of high-dose allovectin-7 in patients with advanced metastatic melanoma

(2010) Agop Y. Bedikian et al.   MELANOMA RESEARCH

Efficient gene delivery by EGF-lipoplexesin vitroandin vivo

(2010) María Buñuales et al.   Nanomedicine

Phospholipid–polyethylenimine conjugate-based micelle-like nanoparticles for siRNA delivery

(2010) Gemma Navarro et al.   Drug Delivery and Translational Research

Nonviral Gene Delivery: Principle, Limitations, and Recent Progress

(2009) Mohammed S. Al-Dosari et al.   AAPS Journal

Cationic liposome–DNA complexes as gene delivery vectors: Development and behaviour towards bone-like cells

(2009) A.C. Oliveira et al.   Acta Biomaterialia

Hyaluronan-CD44 Interactions in Cancer: Paradoxes and Possibilities

(2009) B. P. Toole   CLINICAL CANCER RESEARCH

Activated and non-activated PAMAM dendrimers for gene delivery in vitro and in vivo

(2009) Gemma Navarro et al.   Nanomedicine-Nanotechnology Biology and Medicine

Nanoparticle therapeutics: an emerging treatment modality for cancer

(2008) Mark E. Davis et al.   NATURE REVIEWS DRUG DISCOVERY