Viral Nanoparticle System: An Effective Platform for Photodynamic Therapy

Photodynamic therapy (PDT) is a promising therapy due to its efficiency and accuracy. The photosensitizer is delivered to the target lesion and locally activated. Viral nanoparticles (VNPs) have been explored as delivery vehicles for PDT in recent years because of their favorable properties, including simple manufacture and good safety profile. They have great potential as drug delivery carriers in medicine. Here, we review the development of PDT photosensitizers and discuss applications of VNP-mediated photodynamic therapies and the performance of VNPs in the treatment of tumor cells and antimicrobial therapy. Furthermore, future perspectives are discussed for further developing novel viral nanocarriers or improving existing viral vectors.

Automated summary

Photodynamic therapy (PDT) is a promising treatment method due to its efficiency and accuracy, with viral nanoparticles (VNPs) showing great potential as delivery vehicles for PDT. VNPs have favorable properties and are being explored for applications in tumor cell treatment and antimicrobial therapy, with future prospects focusing on developing novel viral nanocarriers or improving existing viral vectors.