4.7 Article

Dual-Energy X-Ray Dark-Field Material Decomposition

Journal

IEEE TRANSACTIONS ON MEDICAL IMAGING
Volume 40, Issue 3, Pages 974-985

Publisher

IEEE-INST ELECTRICAL ELECTRONICS ENGINEERS INC
DOI: 10.1109/TMI.2020.3043303

Keywords

Imaging; Scattering; Tools; Microstructure; Clinical diagnosis; Spatial resolution; X-ray imaging; Imaging modalities; X-ray imaging and computed tomography; quantification and estimation; lung

Funding

  1. German Research Foundation (DFG) within the Gottfried Wilhelm Leibniz program
  2. European Research Council [AdG 695045]
  3. German Research Foundation (DFG) within the Research Training Group [GRK 2274]

Ask authors/readers for more resources

Dual-energy X-ray imaging and X-ray dark-field imaging are both promising techniques in the field of medical imaging, with the former providing material-specific information and the latter facing challenges in microstructure decomposition. By applying the dual-energy concept to X-ray dark-field imaging, it is possible to address the issue of microstructure decomposition more effectively.
Dual-energy imaging is a clinically well-established technique that offers several advantages over conventional X-ray imaging. By performing measurements with two distinct X-ray spectra, differences in energy-dependent attenuation are exploited to obtain material-specific information. This information is used in various imaging applications to improve clinical diagnosis. In recent years, grating-based X-ray dark-field imaging has received increasing attention in the imaging community. The X-ray dark-field signal originates from ultra small-angle scattering within an object and thus provides information about the microstructure far below the spatial resolution of the imaging system. This property has led to a number of promising future imaging applications that are currently being investigated. However, different microstructures can hardly be distinguished with current X-ray dark-field imaging techniques, since the detected dark-field signal only represents the total amount of ultra small-angle scattering. To overcome these limitations, we present a novel concept called dual-energy X-ray dark-field material decomposition, which transfers the basic material decomposition approach from attenuation-based dual-energy imaging to the dark-field imaging modality. We develop a physical model and algorithms for dual-energy dark-field material decomposition and evaluate the proposed concept in experimental measurements. Our results suggest that by sampling the energy-dependent dark-field signal with two different X-ray spectra, a decomposition into two different microstructured materials is possible. Similar to dual-energy imaging, the additional microstructure-specific information could be useful for clinical diagnosis.

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