Targeting cancer-associated fibroblast-secreted WNT2 restores dendritic cell-mediated antitumour immunity

A new mouse esophageal cancer cell line (mEC25)‐derived pre‐clinical syngeneic tumor model for immunotherapy

(2020) Tuxiong Huang et al.   Cancer Communications

Long non-coding RNA LINC00968 attenuates drug resistance of breast cancer cells through inhibiting the Wnt2/β-catenin signaling pathway by regulating WNT2

(2019) Dian-Hui Xiu et al.   JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH

Mismatch repair deficiency/microsatellite instability-high as a predictor for anti-PD-1/PD-L1 immunotherapy efficacy

(2019) Pengfei Zhao et al.   Journal of Hematology & Oncology

Fibroblast Growth Factor Receptor Signaling in Skin Cancers

(2019) Malgorzata Czyz   Cells

The immune landscape of esophageal cancer

(2019) Tu-Xiong Huang et al.   Cancer Communications

Paracrine Wnt5a-β-Catenin Signaling Triggers a Metabolic Program that Drives Dendritic Cell Tolerization

(2018) Fei Zhao et al.   IMMUNITY

Targeting Wnt/β-Catenin Signaling for Cancer Immunotherapy

(2018) Bojun Wang et al.   TRENDS IN PHARMACOLOGICAL SCIENCES

Wnt2 contributes to the progression of gastric cancer by promoting cell migration and invasion

(2018) Zhaoran Zhang et al.   Oncology Letters

Phase Ib Results of the Rational Combination of Selumetinib and Cyclosporin A in Advanced Solid Tumors with an Expansion Cohort in Metastatic Colorectal Cancer

(2018) Anuradha Krishnamurthy et al.   CANCER RESEARCH

Trial watch: The clinical trial landscape for PD1/PDL1 immune checkpoint inhibitors

(2018) Jun Tang et al.   NATURE REVIEWS DRUG DISCOVERY

Autocrine WNT2 signaling in fibroblasts promotes colorectal cancer progression

(2017) N Kramer et al.   ONCOGENE

Coinhibitory Pathways in Immunotherapy for Cancer

(2016) Susanne H. Baumeister et al.   Annual Review of Immunology

Dendritic Cells and Cancer Immunity

(2016) Alycia Gardner et al.   TRENDS IN IMMUNOLOGY

A Second WNT for Old Drugs: Drug Repositioning against WNT-Dependent Cancers

(2016) Kamal Ahmed et al.   Cancers

Validation of Bone Marrow Derived Dendritic Cells as an Appropriate Model to Study Tumor-Mediated Suppression of DC Maturation through STAT3 Hyperactivation

(2016) Aws Alshamsan et al.   JOURNAL OF PHARMACY AND PHARMACEUTICAL SCIENCES

Classifying Cancers Based on T-cell Infiltration and PD-L1

(2015) Michele W.L. Teng et al.   CANCER RESEARCH

The non-canonical Wnt pathway negatively regulates dendritic cell differentiation by inhibiting the expansion of Flt3+ lymphocyte-primed multipotent precursors

(2015) Jing Xiao et al.   Cellular & Molecular Immunology

Anti–PD-1/PD-L1 therapy of human cancer: past, present, and future

(2015) Lieping Chen et al.   JOURNAL OF CLINICAL INVESTIGATION

Melanoma-intrinsic β-catenin signalling prevents anti-tumour immunity

(2015) Stefani Spranger et al.   NATURE

Clostridium difficile toxin B intoxicated mouse colonic epithelial CT26 cells stimulate the activation of dendritic cells

(2015) Tuxiong Huang et al.   Pathogens and Disease

SOCS3 in immune regulation of inflammatory bowel disease and inflammatory bowel disease-related cancer

(2012) Yi Li et al.   CYTOKINE & GROWTH FACTOR REVIEWS

WNT2promoter methylation in human placenta is associated with low birthweight percentile in the neonate

(2011) Jose Carlos Ferreira et al.   Epigenetics

Wnt2 secreted by tumour fibroblasts promotes tumour progression in oesophageal cancer by activation of the Wnt/ -catenin signalling pathway

(2011) L. Fu et al.   GUT

Immunotherapy targeting fibroblast activation protein inhibits tumor growth and increases survival in a murine colon cancer model

(2010) Yuan Wen et al.   CANCER SCIENCE

Dendritic Cell (DC)-Specific Targeting Reveals Stat3 as a Negative Regulator of DC Function

(2010) Jessica A. Melillo et al.   JOURNAL OF IMMUNOLOGY

Loss of Jak2 Selectively Suppresses DC-Mediated Innate Immune Response and Protects Mice from Lethal Dose of LPS-Induced Septic Shock

(2010) Jixin Zhong et al.   PLoS One

Suppression of Antitumor Immunity by Stromal Cells Expressing Fibroblast Activation Protein- 

(2010) M. Kraman et al.   SCIENCE

Signaling from Fibroblast Growth Factor Receptor 2 in Immature Hematopoietic Cells Facilitates Donor Hematopoiesis After Intra-Bone Marrow–Bone Marrow Transplantation

(2010) Akio Shigematsu et al.   STEM CELLS AND DEVELOPMENT

Fibroblast Growth Factor Receptor 2-Positive Fibroblasts Provide a Suitable Microenvironment for Tumor Development and Progression in Esophageal Carcinoma

(2009) C. Zhang et al.   CLINICAL CANCER RESEARCH

Notch and Wingless Signaling Cooperate in Regulation of Dendritic Cell Differentiation

(2009) Jie Zhou et al.   IMMUNITY

Fibroblast growth factor-2 and its receptor expression in proliferating precursor cells of the subventricular zone in the adult rat brain

(2008) Monica Frinchi et al.   NEUROSCIENCE LETTERS