Omega‐3 fatty acids protect from colitis via an Alox15‐derived eicosanoid

Human lipoxygenase isoforms form complex patterns of double and triple oxygenated compounds from eicosapentaenoic acid

(2020) Laura Kutzner et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS

MS-based targeted metabolomics of eicosanoids and other oxylipins: Analytical and inter-individual variabilities

(2019) Cécile Gladine et al.   FREE RADICAL BIOLOGY AND MEDICINE

Pro- and anti-inflammatory eicosanoids in psoriatic arthritis

(2019) Roxana Coras et al.   Metabolomics

Female mice carrying a defective Alox15 gene are protected from experimental colitis via sustained maintenance of the intestinal epithelial barrier function

(2018) Saskia Kroschwald et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS

The evolutionary hypothesis of reaction specificity of mammalian ALOX15 orthologs

(2018) Hartmut Kuhn et al.   PROGRESS IN LIPID RESEARCH

Endogenous Omega (n)-3 Fatty Acids in Fat-1 Mice Attenuated Depression-Like Behavior, Imbalance between Microglial M1 and M2 Phenotypes, and Dysfunction of Neurotrophins Induced by Lipopolysaccharide Administration

(2018) Minqing Gu et al.   Nutrients

Leukotriene-mediated sex dimorphism in murine asthma-like features during allergen sensitization

(2018) Antonietta Rossi et al.   PHARMACOLOGICAL RESEARCH

Protectin D1n-3 DPAand resolvin D5n-3 DPAare effectors of intestinal protection

(2017) Thomas Gobbetti et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Modulation of the endogenous omega-3 fatty acid and oxylipin profile in vivo—A comparison of the fat-1 transgenic mouse with C57BL/6 wildtype mice on an omega-3 fatty acid enriched diet

(2017) Annika I. Ostermann et al.   PLoS One

Development of an LC-ESI(-)-MS/MS method for the simultaneous quantification of 35 isoprostanes and isofurans derived from the major n3- and n6-PUFAs

(2017) Katharina M. Rund et al.   ANALYTICA CHIMICA ACTA

Defects in 15-HETE Production and Control of Epithelial Permeability by Human Enteric Glial Cells From Patients With Crohn’s Disease

(2016) Camille Pochard et al.   GASTROENTEROLOGY

Evolutionary alteration of ALOX15 specificity optimizes the biosynthesis of antiinflammatory and proresolving lipoxins

(2016) Susan Adel et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Mammalian lipoxygenases and their biological relevance

(2015) Hartmut Kuhn et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS

A soybean and fish oil mixture with different n-6/n-3 PUFA ratios modulates the inflammatory reaction in mice with dextran sulfate sodium-induced acute colitis

(2015) Cyoung-Huei Huang et al.   CLINICAL NUTRITION

The gut microbiota and inflammatory bowel disease

(2015) Yoshiyuki Goto et al.   CURRENT OPINION IN RHEUMATOLOGY

The global burden of IBD: from 2015 to 2025

(2015) Gilaad G. Kaplan   Nature Reviews Gastroenterology & Hepatology

Resolution phase lipid mediators of inflammation: agonists of resolution

(2013) Charles N. Serhan et al.   CURRENT OPINION IN PHARMACOLOGY

Maresin 1, a Proresolving Lipid Mediator Derived from Omega-3 Polyunsaturated Fatty Acids, Exerts Protective Actions in Murine Models of Colitis

(2013) R. Marcon et al.   JOURNAL OF IMMUNOLOGY

Resolvins and Protectins in Inflammation Resolution

(2011) Charles N. Serhan et al.   CHEMICAL REVIEWS

Omega-3 Fatty Acid-Derived Mediators 17(R)-Hydroxy Docosahexaenoic Acid, Aspirin-Triggered Resolvin D1 and Resolvin D2 Prevent Experimental Colitis in Mice

(2011) A. F. Bento et al.   JOURNAL OF IMMUNOLOGY

Lipoxin and Aspirin-Triggered Lipoxins

(2011) Mario Romano   TheScientificWorldJOURNAL

Mechanisms for anti-inflammatory effects of 1-[15(S)-hydroxyeicosapentaenoyl] lysophosphatidylcholine, administered intraperitoneally, in zymosan A-induced peritonitis

(2010) Nguyen Dang Hung et al.   BRITISH JOURNAL OF PHARMACOLOGY

Resolvin E1-induced intestinal alkaline phosphatase promotes resolution of inflammation through LPS detoxification

(2010) E. L. Campbell et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Resolvin E1, an endogenous lipid mediator derived from eicosapentaenoic acid, prevents dextran sulfate sodium–induced colitis

(2009) Tsukasa Ishida et al.   INFLAMMATORY BOWEL DISEASES

ERK-mediated regulation of leukotriene biosynthesis by androgens: A molecular basis for gender differences in inflammation and asthma

(2008) C. Pergola et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA