Nrf2 as a therapeutic target in ischemic stroke

Activation of Nrf2 by Natural Bioactive Compounds: A Promising Approach for Stroke?

(2020) Agnese Gugliandolo et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Critical Role of Nrf2 in Experimental Ischemic Stroke

(2019) Lei Liu et al.   Frontiers in Pharmacology

Pharmacokinetics and pharmacodynamics of the novel Nrf2 activator omaveloxolone in primates

(2019) Scott A Reisman et al.   Drug Design Development and Therapy

Isoquercetin attenuates oxidative stress and neuronal apoptosis after ischemia/reperfusion injury via Nrf2-mediated inhibition of the NOX4/ROS/NF-κB pathway

(2018) Yunyi Dai et al.   CHEMICO-BIOLOGICAL INTERACTIONS

Liraglutide Activates the Nrf2/HO-1 Antioxidant Pathway and Protects Brain Nerve Cells against Cerebral Ischemia in Diabetic Rats

(2018) Caihong Deng et al.   Computational Intelligence and Neuroscience

Safety, pharmacodynamics, and potential benefit of omaveloxolone in Friedreich ataxia

(2018) David R. Lynch et al.   Annals of Clinical and Translational Neurology

Seasonal heat stress affects adipose tissue proteome toward enrichment of the Nrf2-mediated oxidative stress response in late-pregnant dairy cows

(2017) M. Zachut et al.   Journal of Proteomics

Sulforaphane reduces hepatic glucose production and improves glucose control in patients with type 2 diabetes

(2017) Annika S. Axelsson et al.   Science Translational Medicine

Nrf2—a Promising Therapeutic Target for Defensing Against Oxidative Stress in Stroke

(2016) Rongrong Zhang et al.   MOLECULAR NEUROBIOLOGY

Lack of Effect of Oral Sulforaphane Administration on Nrf2 Expression in COPD: A Randomized, Double-Blind, Placebo Controlled Trial

(2016) Robert A. Wise et al.   PLoS One

The complexity of the Nrf2 pathway: beyond the antioxidant response

(2015) Ying Huang et al.   JOURNAL OF NUTRITIONAL BIOCHEMISTRY

Dietary flavonoids are neuroprotective through Nrf2-coordinated induction of endogenous cytoprotective proteins

(2011) Christopher C. Leonardo et al.   NUTRITIONAL NEUROSCIENCE

Expression of Keap1–Nrf2 system and antioxidative proteins in mouse brain after transient middle cerebral artery occlusion

(2010) Nobuhito Tanaka et al.   BRAIN RESEARCH