Review
Medicine, General & Internal
Angkana Lekagul, Peeraya Piancharoen, Anamika Chattong, Chawisa Suradom, Viroj Tangcharoensathien
Summary: This review assesses the effectiveness of interventions in mitigating psychological consequences during the COVID-19 pandemic. The results indicate that interventions targeting anxiety and depression are effective in reducing psychological consequences and can be applied to healthcare workers, patients with COVID-19, and the general population.
Review
Psychiatry
Eve-Line Bussieres, Catherine Malboeuf-Hurtubise, A. Meilleur, Trinity Mastine, Elodie Herault, Nicholas Chadi, Marjorie Montreuil, Melissa Genereux, Chantal Camden
Summary: The COVID-19 pandemic has negatively impacted the mental health of children aged 5-13, especially those with neurodevelopmental issues or chronic health conditions. More research is needed to understand the long-term effects of the pandemic on children's mental health.
FRONTIERS IN PSYCHIATRY
(2021)
Article
Psychiatry
Matthias Favreau, Andreas Hillert, Bernhard Osen, Thomas Gartner, Sandra Hunatschek, Moritz Riese, Karina Hewera, Ulrich Voderholzer
Summary: The study indicates that during the COVID-19 pandemic, patients with mental disorders are generally affected by symptom deterioration and impaired treatment, with eating disorders and depressive disorders particularly more frequently affected. There is a need for improved treatment options during a pandemic.
PSYCHIATRY RESEARCH
(2021)
Review
Public, Environmental & Occupational Health
Matias Irarrazaval, Pablo Norambuena, Cristian Montenegro, Olga Toro-Devia, Belen Vargas, Alejandra Caqueo-Urizar
Summary: This paper reviews the mental health policies implemented in Chile in response to COVID-19 and compares them with international experiences. Five crucial points of action were identified in Chile, with a coordinated implementation of mental health plans. However, increased funding and promoting participation of communities are imperative for social peace and recovery after the pandemic.
FRONTIERS IN PUBLIC HEALTH
(2021)
Article
Medicine, General & Internal
Lyndsay A. Avalos, G. Thomas Ray, Stacey E. Alexeeff, Sara R. Adams, Monique B. Does, Carey Watson, Kelly C. Young-Wolff
Summary: This study investigated trends in unstable and/or unsafe living situations and intimate partner violence (IPV) among pregnant individuals before and during the COVID-19 pandemic. The results showed an overall increase in these issues over the 24-month period, with a temporary increase associated with the pandemic. The findings highlight the importance of including IPV safeguards and support services in emergency response plans for future pandemics.
Review
Nursing
Karin Hugelius, Nahoko Harada, Miki Marutani
Summary: Visitor restrictions during the COVID-19 pandemic have had mainly negative consequences on patients, family members, and care providers, affecting physical and mental health of patients, causing worry and anxiety in family members, and adding burdens on care providers. Further studies are needed to better understand the effects of visiting restrictions.
INTERNATIONAL JOURNAL OF NURSING STUDIES
(2021)
Article
Psychology, Multidisciplinary
Ahmed Msherghi, Ali Alsuyihili, Ahmed Alsoufi, Aimen Ashini, Zenib Alkshik, Entisar Alshareea, Hanadi Idheiraj, Taha Nagib, Munera Abusriwel, Nada Mustafa, Fatima Mohammed, Ayah Eshbeel, Abobaker Elbarouni, Muhammed Elhadi
Summary: This study provided an overview of the psychological and behavioral status among the Libyan population during the COVID-19 lockdown in Libya. The results showed a high level of clinically significant anxiety symptoms during the lockdown period, with predictors including gender, age, marital status, work status, financial support for the family, and COVID-19 infection.
FRONTIERS IN PSYCHOLOGY
(2021)
Article
Psychiatry
Sydney Bornstein, Manya Magnus
Summary: The COVID-19 pandemic has led to an increase in loneliness, and younger age, depression, and living alone are significantly associated with increased feelings of loneliness.
PSYCHIATRY RESEARCH
(2022)
Article
Medicine, General & Internal
Haruka Sakamoto, Masahiro Ishikane, Cyrus Ghaznavi, Peter Ueda
Summary: The study found that suicide rates in Japan increased in October and November for men and in July through November for women in 2020 compared to previous years.
Article
Psychology, Multidisciplinary
Esther-Sevil Eigl, Sebastian Stefan Widauer, Manuel Schabus
Summary: This study evaluates the psychosocial burden and impairments of children and adolescents in Austria during the COVID-19 pandemic. The results show that most children experience fear, with females experiencing higher emotional strain than males. The overestimation of COVID-19 hospitalization risk, lack of positive perspective, and frequent reports of negative emotions highlight the impact of the pandemic on children.
FRONTIERS IN PSYCHOLOGY
(2022)
Article
Health Care Sciences & Services
Malin Lohela-Karlsson, Emelie Conden Mellgren
Summary: This study compared the health consequences among Swedish healthcare workers involved in the care of COVID-19 patients. The results showed that HCWs directly involved in COVID-19 care experienced poorer sleep quality and higher levels of emotional and physical exhaustion. There were no significant differences in health consequences among different occupational groups involved in COVID-19 care.
Article
Environmental Sciences
Fabiula Danielli Bastos de Sousa
Summary: Plastic plays a crucial role in pandemic times, serving both as a lifesaver and a source of environmental pollution. This work explores the main applications and environmental impacts of plastic during the COVID-19 pandemic, offering some potential solutions to the issues at hand.
ENVIRONMENTAL SCIENCE AND POLLUTION RESEARCH
(2021)
Review
Public, Environmental & Occupational Health
Chaochao Wang, Zuguo Tian, Qiaoyou Luo
Summary: Exercise can alleviate anxiety, depression, stress levels, and improve quality of life during the COVID-19 pandemic. The most significant impact on anxiety and depression improvement is achieved by engaging in 30-40 min exercise sessions, 3-5 times per week. In the 40-64 age group, exercise has the most significant impact on improving depression. Furthermore, exercise notably enhances anxiety levels among individuals in middle and upper-income brackets.
FRONTIERS IN PUBLIC HEALTH
(2023)
Review
Psychology, Multidisciplinary
Ping Sun, Manli Wang, Tingting Song, Yan Wu, Jinglu Luo, Lili Chen, Lei Yan
Summary: The COVID-19 pandemic has caused significant psychological impact on healthcare workers, particularly among women and frontline workers, leading to high prevalence of anxiety, depression, and insomnia. Timely psychological counseling and intervention are crucial to alleviate their anxiety and improve their overall mental health.
FRONTIERS IN PSYCHOLOGY
(2021)
Review
Health Care Sciences & Services
Christian Rauschenberg, Anita Schick, Dusan Hirjak, Andreas Seidler, Isabell Paetzold, Christian Apfelbacher, Steffi G. Riedel-Heller, Ulrich Reininghaus
Summary: This study reviewed the theoretical and empirical base, user perspective, safety, effectiveness, and cost-effectiveness of digital interventions related to public mental health. The findings suggest good evidence on eHealth interventions and promising evidence on mHealth apps, with limited evidence on long-term effects and cost-effectiveness. Digital interventions are seen as particularly well-suited for mitigating psychosocial consequences at the population level during times of physical distancing and social restrictions.
JOURNAL OF MEDICAL INTERNET RESEARCH
(2021)
Article
Psychology, Developmental
Sayuri Nakane, Sachiko Tanaka-Mizuno, Chika Nishiyama, Kenji Kochi, Madoka Yamamoto-Sasaki, Masato Takeuchi, Yusuke Ogawa, Yuko Doi, Masaru Arai, Yosuke Fujii, Toshiyuki Matsunaga, Toshiaki A. Furukawa, Koji Kawakami
Summary: Little is known about the prescription patterns of antipsychotic drugs among children and adolescents in Japan, particularly in outpatient settings. This study investigated the prevalence and trends of antipsychotic prescription among outpatients aged <= 17 years from 2006 to 2012. The results showed that the most common prescription pattern was second-generation antipsychotic monotherapy, with risperidone being the most frequently prescribed drug.
CHILD PSYCHIATRY & HUMAN DEVELOPMENT
(2023)
Article
Clinical Neurology
Felix Brandl, Franziska Knolle, Mihai Avram, Claudia Leucht, Igor Yakushev, Josef Priller, Stefan Leucht, Sibylle Ziegler, Klaus Wunderlich, Christian Sorg
Summary: Negative symptoms in patients with schizophrenia are highly prevalent and debilitating. This study found that impaired model-free reward prediction influence is a mechanism for negative symptoms in schizophrenia, and it is associated with reduced associative striatum dopamine and executive dysfunction.
Article
Pharmacology & Pharmacy
Myrto T. Samara, Stephen Z. Levine, Stefan Leucht
Summary: The study aims to understand and interpret the clinical significance of the Young Mania Rating Scale (YMRS) scores by examining their linkages with the Clinical Global Impression (CGI) ratings. The results of the study provide clinicians with meaningful cutoff values to interpret YMRS scores, which can contribute to the definition of treatment targets, response, remission, and entry criteria in mania trials.
PHARMACOPSYCHIATRY
(2023)
Letter
Psychology, Clinical
Yan Luo, Toshi A. Furukawa
PSYCHOLOGICAL MEDICINE
(2023)
Article
Medicine, General & Internal
Yusuke Tsutsumi, Yasushi Tsujimoto, Aran Tajika, Kenji Omae, Tomoko Fujii, Akira Onishi, Yuki Kataoka, Morihiro Katsura, Hisashi Noma, Ethan Sahker, Edoardo Giuseppe Ostinelli, Toshi A. Furukawa
Summary: The study examines the magnitude and variability of contextual effects (PCE) in placebo-controlled trials across various interventions. The results show that subjective outcomes are influenced more by specific intervention effects compared to objective or semiobjective outcomes. The study highlights the importance of considering each PCE individually in different clinical settings.
BMJ EVIDENCE-BASED MEDICINE
(2023)
Article
Oncology
Tatsuo Akechi, Takuhiro Yamaguchi, Megumi Uchida, Fuminobu Imai, Kanae Momino, Fujika Katsuki, Naomi Sakurai, Tempei Miyaji, Tomoe Mashiko, Masaru Horikoshi, Toshi A. Furukawa, Akiyo Yoshimura, Shinji Ohno, Natsue Uehiro, Kenji Higaki, Yoshie Hasegawa, Kazuhisa Akahane, Yosuke Uchitomi, Hiroji Iwata
Summary: This study investigated the effectiveness of smartphone problem-solving therapy and behavioral activation applications in breast cancer survivors. The results showed that smartphone psychotherapy offers a promising way to reduce fear of cancer recurrence in this population.
JOURNAL OF CLINICAL ONCOLOGY
(2023)
Article
Psychiatry
Katharine A. Smith, Louise M. Howard, Simone N. Vigod, Armando D'Agostino, Andrea Cipriani
Summary: The COVID-19 pandemic has exacerbated inequalities and risk factors for mental disorders, especially in perinatal mental health. Access to services has been reduced and perinatal anxiety and depressive symptoms have increased. Telepsychiatry offers advantages, but further examination is needed. Clinicians will need expertise in navigating a hybrid model and there is a need for urgent and coordinated guidance and planning across organizations involved in perinatal mental health care.
AUSTRALIAN AND NEW ZEALAND JOURNAL OF PSYCHIATRY
(2023)
Article
Mathematical & Computational Biology
Orestis Efthimiou, Jeroen Hoogland, Thomas P. A. Debray, Michael Seo, Toshiaki A. Furukawa, Matthias Egger, Ian R. White
Summary: When individual patient data from a randomized trial are available, statistical and machine learning methods can be used to develop models for predicting treatment effects and guide personalized treatment choices. This article proposes measures to evaluate personalized treatment effect predictions, including discrimination and calibration. The methods are applicable to different outcome types and prediction models.
STATISTICS IN MEDICINE
(2023)
Article
Mathematical & Computational Biology
Tasnim Hamza, Konstantina Chalkou, Fabio Pellegrini, Jens Kuhle, Pascal Benkert, Johannes Lorscheider, Chiara Zecca, Cynthia P. Iglesias-Urrutia, Andrea Manca, Toshi A. Furukawa, Andrea Cipriani, Georgia Salanti
Summary: In network meta-analysis (NMA), all relevant evidence about health outcomes with competing treatments is synthesized. The evidence can come from randomized clinical trials (RCT) or non-randomized studies (NRS) as individual participant data (IPD) or aggregate data (AD). A suite of Bayesian NMA and network meta-regression (NMR) models are introduced to allow for cross-design and cross-format synthesis. The models integrate a three-level hierarchical model for synthesizing IPD and AD into four approaches, accounting for differences in design and risk of bias (RoB) in the evidence.
RESEARCH SYNTHESIS METHODS
(2023)
Review
Clinical Neurology
Leonie Reichelt, Orestis Efthimiou, Stefan Leucht, Johannes Schneider-Thoma
Summary: This study compares the risk of seizures between second-generation antipsychotics and placebo in randomized controlled clinical trials (RCTs), and finds that there is no evidence to suggest that second-generation antipsychotics cause seizures in most diagnostic groups.
EUROPEAN NEUROPSYCHOPHARMACOLOGY
(2023)
Article
Health Care Sciences & Services
Catherine Henshall, Zoe Davey, Cynthia Srikesavan, Liam Hart, Dan Butcher, Andrea Cipriani
Summary: This study aimed to examine the engagement and acceptability of a web-based resilience training program for nurses and to compare the levels of resilience and psychological well-being between participants who completed the program and those who did not. The results showed that the program was acceptable, engaging, and perceived as useful by the participants, suggesting the need for similar programs to be evaluated in busy healthcare settings.
JOURNAL OF MEDICAL INTERNET RESEARCH
(2023)
Article
Clinical Neurology
Shimeng Dong, Johannes Schneider-Thoma, Irene Bighelli, Spyridon Siafis, Dongfang Wang, Angelika Burschinski, Kristina Schestag, Myrto Samara, Stefan Leucht
Summary: In this network meta-analysis, the efficacy and adverse events of different antipsychotics in treatment-resistant schizophrenia were examined. The results showed that clozapine and olanzapine were more effective in relieving symptoms compared to other drugs. Clozapine remains the gold standard for patients with treatment-resistant schizophrenia, while olanzapine can be considered as an alternative option.
EUROPEAN ARCHIVES OF PSYCHIATRY AND CLINICAL NEUROSCIENCE
(2023)
Article
Mathematical & Computational Biology
Hisashi Noma, Yasuyuki Hamura, Shonosuke Sugasawa, Toshi A. Furukawa
Summary: Network meta-analysis has been widely used in evidence-based medicine to evaluate the effectiveness of multiple treatments. The prediction interval, which incorporates uncertainties and heterogeneity, is an important output of network meta-analysis. However, current standard methods based on t-distribution have been found to underestimate uncertainty in realistic situations. In this study, we propose two new methods based on bootstrap and Kenward-Roger adjustment to construct more accurate prediction intervals.
RESEARCH SYNTHESIS METHODS
(2023)
Article
Psychiatry
Qiang Liu, Edoardo Giuseppe Ostinelli, Franco De Crescenzo, Zhenpeng Li, Anneka Tomlinson, Georgia Salanti, Andrea Cipriani, Orestis Efthimiou
Summary: When developing prediction models, researchers commonly use either an end-to-end approach or a similarity-based approach to address heterogeneity in patient characteristics. This study compared the performance of these two approaches using data from patients with depression and found that they yielded comparable results.
Article
Psychology, Clinical
Ryuhei So, Naoki Emura, Kozue Okazaki, Sakiko Takeda, Takashi Sunami, Kohei Kitagawa, Yoshitake Takebayashi, Toshi A. Furukawa
Summary: This study compared the effects of therapist-guided internet interventions with unguided ones on gambling behavior, cognition, and stage of change. The results showed that there were no significant differences between the guided and unguided groups in terms of improvement in gambling symptoms, behavior, and stage of change.
ADDICTIVE BEHAVIORS
(2024)
